RESUMEN
The experience of surgical treatment of 50 patients for varicose disease of lower extremities, complicated by trophic ulcers, in the presence of diabetes mellitus type II were analysed. During surgery in patients of the 1st group performed a combined phlebectomy, group 2--scleroobliteration and echoscleroobliteration. Using fleboscleroobliteration method helped reduce the frequency of early postoperative complications in (6.5 +/- 1.3) times.
Asunto(s)
Diabetes Mellitus Tipo 2/cirugía , Pie Diabético/cirugía , Extremidad Inferior/cirugía , Escleroterapia/métodos , Úlcera Varicosa/cirugía , Adulto , Anciano , Diabetes Mellitus Tipo 2/complicaciones , Diabetes Mellitus Tipo 2/diagnóstico por imagen , Diabetes Mellitus Tipo 2/patología , Pie Diabético/complicaciones , Pie Diabético/diagnóstico por imagen , Pie Diabético/patología , Femenino , Hematoma/etiología , Hematoma/patología , Humanos , Extremidad Inferior/irrigación sanguínea , Extremidad Inferior/diagnóstico por imagen , Extremidad Inferior/patología , Masculino , Persona de Mediana Edad , Parestesia/etiología , Parestesia/patología , Complicaciones Posoperatorias , Periodo Posoperatorio , Escleroterapia/instrumentación , Resultado del Tratamiento , Ultrasonografía , Úlcera Varicosa/complicaciones , Úlcera Varicosa/diagnóstico por imagen , Úlcera Varicosa/patologíaAsunto(s)
Antibacterianos/uso terapéutico , Cefalosporinas/uso terapéutico , Pie Diabético/tratamiento farmacológico , Penicilinas/uso terapéutico , Pie Diabético/microbiología , Pie Diabético/patología , Pie Diabético/cirugía , Farmacorresistencia Bacteriana , Investigación Empírica , Humanos , Estudios Prospectivos , Estudios Retrospectivos , SíndromeRESUMEN
The results of investigation on impact of the foam form of sclerosant in experiment on 80 mongrel white rats, were presented. Sclerosing action of 0.5%, 2%, 3% solution of polydocanol in a microfoam form was studied after its infusion into lateral caudal vein of the rat. Quantity of preparation 0,5 cm3 was determined in accordance to the vein volume. Clinical and macroscopic estimation of the preparation action on internal organs and caudal rat's vein was conducted on the 10th min, every day during 1 week and on the 30th day. When the foam form of sclerosant is introduced intravenously there was not observed thrombotic complications of posterior vena cava and specific macroscopic changes in internal organs, not depending from its concentration, what witnesses security of the method, and selection of the sclerosant solution concentration must depend on the vessel diameter.
Asunto(s)
Polietilenglicoles/administración & dosificación , Soluciones Esclerosantes/administración & dosificación , Escleroterapia , Cola (estructura animal)/irrigación sanguínea , Várices/terapia , Animales , Formas de Dosificación , Masculino , Polidocanol , Polietilenglicoles/efectos adversos , Ratas , Soluciones Esclerosantes/efectos adversosRESUMEN
The results of ambulatory application of subfascial endoscopic dissection of perforant veins (SEDPV) in 47 patients, suffering C4-C5 functional class varicose disease (according to CEAP classification) were presented. In all the patients SEDPV was performed in combination with miniinvasive methods of vertical reflux and varicosely changed tributaries elimination. The complications have had occurred in 6 (12.77%) patients, but they were not severe, did not need secondary hospitalisation of the patients, did not impact essentially restoration of ability to work and did not worsened the treatment outcome. Duration of inability to work period have lasted 12 - 25 days after the operation, 14.7 days at average. There was proved, that SEDPV permits to perform radical surgical intervention in patients, suffering chronic venous insufficiency class C4-C5 in ambulatory conditions.
Asunto(s)
Procedimientos Quirúrgicos Ambulatorios/métodos , Procedimientos Endovasculares/métodos , Fasciotomía , Várices/cirugía , Insuficiencia Venosa/cirugía , Adulto , Anciano , Femenino , Humanos , Masculino , Persona de Mediana Edad , Resultado del Tratamiento , Várices/diagnóstico , Insuficiencia Venosa/diagnósticoRESUMEN
The results of ambulatory surgical treatment for the 2007 - 2012 yrs period of 736 patients, suffering varicose disease of lower extremities (VDLE) with chronic venous insufficiency Class C0-C6, according to CEAP (Clinical Etiological Anatomical Pathophysiological) classification, were analyzed. In 258 patients intraoperative truncal scleroobliteration was used and in 124 -endovenous laser coagulation, in 47 - subfascial endoscopic dissection of perforant veins, in 307 - microsclerotherapy, compressive treatment, medicinal therapy. The treatment algorithm of ambulatory surgery of VDLE was elaborated, basing on the analysis of the results of treatment.
Asunto(s)
Algoritmos , Procedimientos Quirúrgicos Ambulatorios/normas , Extremidad Inferior/cirugía , Várices/cirugía , Insuficiencia Venosa/cirugía , Procedimientos Quirúrgicos Ambulatorios/métodos , Endoscopía/métodos , Femenino , Humanos , Coagulación con Láser/métodos , Extremidad Inferior/irrigación sanguínea , Extremidad Inferior/patología , Masculino , Escleroterapia/métodos , Várices/patología , Insuficiencia Venosa/patologíaRESUMEN
Character of microflora in patients with infection complications of diabetic foot syndrome was analyzed. The efficacy of modern antibacterial preparations for empirical and specific therapy was studied up.
Asunto(s)
Antibacterianos/uso terapéutico , Pie Diabético/tratamiento farmacológico , Adulto , Anciano , Anciano de 80 o más Años , Antibacterianos/administración & dosificación , Pie Diabético/microbiología , Pie Diabético/patología , Quimioterapia Combinada , Femenino , Humanos , Masculino , Persona de Mediana Edad , Necrosis , Supuración , Resultado del TratamientoRESUMEN
Experience of treatment of 135 patients for varicose disease (VD) of lower extremities (VLE) was analyzed. The investigation objective was the elimination of adverse reactions of general anesthesia and minimization of surgical trauma without loss of the operation radicalism. In 112 (83%) patients a crossectomy (upper and/or lower) was conducted under local infiltrating anesthesia. The criterion for the patients choice for the operation in conditions of local anesthesia was the presence of a VD, independent of its stage. In the investigation were not included the patients, suffering a VD recurrence and its decompensated forms. Our experience witness, that in a certain level of a surgeon qualification present, in a majority of patients, suffering VDLE, including its complicated forms, crossectomy may be performed in conditions of a local anesthesia.
Asunto(s)
Anestesia Local , Procedimientos Quirúrgicos Mínimamente Invasivos/métodos , Várices/cirugía , Procedimientos Quirúrgicos Vasculares/métodos , Adulto , Anciano , Femenino , Humanos , Masculino , Persona de Mediana Edad , Resultado del Tratamiento , Adulto JovenAsunto(s)
Diabetes Mellitus Tipo 1/complicaciones , Diabetes Mellitus Tipo 2/complicaciones , Pie Diabético/cirugía , Procedimientos Quirúrgicos Operativos/métodos , Adulto , Anciano , Anciano de 80 o más Años , Diabetes Mellitus Tipo 1/epidemiología , Diabetes Mellitus Tipo 1/cirugía , Diabetes Mellitus Tipo 2/epidemiología , Diabetes Mellitus Tipo 2/cirugía , Pie Diabético/epidemiología , Pie Diabético/etiología , Femenino , Humanos , Masculino , Persona de Mediana Edad , Resultado del TratamientoAsunto(s)
Médula Ósea/efectos de los fármacos , Colecalciferol/farmacología , Linfocitos/citología , Animales , Células de la Médula Ósea , Diferenciación Celular/efectos de los fármacos , Granulocitos/citología , Granulocitos/efectos de los fármacos , Hematopoyesis/efectos de los fármacos , Recuento de Leucocitos , Linfocitos/efectos de los fármacos , Ratones , Ratones Endogámicos BALB C , Ratones Endogámicos C57BLRESUMEN
Normal and irradiated fibrinogen, gamma-globulins, alpha- and beta-globulins and albumins of blood plasma were shown to contain squalene, lathosterol, cholesterol and some other compounds as lipid components. Radiation alteration of the total number of unsaponifiable substances and some lipid components in the individual blood plasma proteins followed certain regularities depending on the kind of a protein. The level of radiation changes in the content of lipid components in specific proteins of blood plasma was shown to be a function of radiation dose and time after irradiation.
Asunto(s)
Proteínas Sanguíneas/química , Colesterol/sangre , Traumatismos Experimentales por Radiación/sangre , Escualeno/sangre , Animales , Masculino , Ratas , Ratas EndogámicasRESUMEN
Ionizing radiation causes considerable changes in the content of sterols and squalene in the lymphoid system tissues and erythrocyte membranes which is in accordance with the concept of high radiosensitivity of haemopoietic tissue. The processes of cholesterol conversion to its oxy-derivatives are increased under the effect of radiation. The content of some lipid components in the lymphoid system tissues and erythrocyte membranes is changed depending on the dose and time after irradiation. There is a relationship between the changes in the sterol composition and in the properties of erythrocyte membranes.
Asunto(s)
Membrana Eritrocítica/metabolismo , Tejido Linfoide/metabolismo , Traumatismos Experimentales por Radiación/metabolismo , Escualeno/metabolismo , Esteroles/metabolismo , Animales , Membrana Eritrocítica/efectos de la radiación , Tejido Linfoide/efectos de la radiación , Masculino , Ratas , Ratas EndogámicasRESUMEN
In 13 patients, the diagnosis of abscesses and subsequent puncture treatment were performed under echotomoscopic guidance, in 4--simultaneous laparoscopy was used. In 2 patients, the puncture method of treatment has proved to be ineffective, and they required the abscess opening. One female patient died from abscessed primary hepatic cancer.
Asunto(s)
Absceso/cirugía , Absceso Hepático/cirugía , Peritonitis/cirugía , Succión/métodos , Adulto , Humanos , Cuidados Intraoperatorios , Laparoscopía , Persona de Mediana Edad , Punciones , UltrasonografíaRESUMEN
Ten years of experience in the work of specialized pulmonary centre providing care for the population of the region has indicated that during this period it has had a major impact on health care delivery and quality of care for the pulmonary patients. There has been improvement in early diagnosis and outcomes of treatment in patients with pulmonary diseases. The primary invalidism associated with chronic non-specific lung diseases has tended to decrease.
Asunto(s)
Hospitales de Distrito/organización & administración , Hospitales Públicos/organización & administración , Enfermedades Pulmonares/terapia , Servicio Ambulatorio en Hospital/organización & administración , Neumología , Humanos , Enfermedades Pulmonares/diagnóstico , Derivación y Consulta , UcraniaRESUMEN
Comparative data are presented on the effect of hypolipidemic agents on the content and composition of sterol-fibrinogen complexes of the blood in patients with ischemic heart disease. Inclusion of heparin, miscleron, complamin in the complex treatment was accompanied by a distinct reduction of the concentration of sterol-fibrinogen complexes, normalization of the ratio of polar sterols. The employment of miscleron and heparin furthered a reduction of the load of sterols on fibrinogen. The use of diosponin did not essentially effect the above-mentioned values.
Asunto(s)
Enfermedad Coronaria/sangre , Fibrinógeno/análisis , Hipolipemiantes/uso terapéutico , Esteroles/sangre , Angina de Pecho/sangre , Angina de Pecho/tratamiento farmacológico , Enfermedad Coronaria/tratamiento farmacológico , Evaluación de Medicamentos , Quimioterapia Combinada , Femenino , Humanos , Masculino , Persona de Mediana Edad , Factores de TiempoAsunto(s)
Conductos Biliares/cirugía , Colestasis Extrahepática/cirugía , Duodeno/cirugía , Esfinterotomía Transduodenal , Adulto , Anciano , Anciano de 80 o más Años , Anastomosis Quirúrgica , Coledocostomía , Colestasis Extrahepática/etiología , Urgencias Médicas , Femenino , Cálculos Biliares/cirugía , Humanos , Masculino , Persona de Mediana Edad , Planificación de Atención al PacienteRESUMEN
Contents of scvalene, sterols and their derivatives were studied in lymphoid tissues as well as in liver and kidney tissues of normal rats and the animals with Shvetz experimental leukosis. Amount of cholesterol and of its precursor scvalene was distinctly decreased simultaneously with an increase in total content of nonsaponified substances in thymus, spleen, bone marrow and liver tissue of rats with experimental leukosis. Scvalene was increased in kidney tissue. Simultaneous accumulation of hydroxycholesterol derivatives, among which 7-beta-hydroxycholesterol was identified, was observed in these tissues under conditions of leukosis. Role of cholesterol hydroxyderivatives in biosynthesis of sterols is discussed.
Asunto(s)
Médula Ósea/metabolismo , Leucemia Experimental/metabolismo , Hígado/metabolismo , Linfocitos/metabolismo , Escualeno/metabolismo , Esteroles/metabolismo , Animales , Masculino , Ratas , Valores de Referencia , Bazo/metabolismo , Timo/metabolismoRESUMEN
Amount of cholesterol was distinctly decreased but content of scvalene, lanosterol, 7-dehydrocholesterol and 7-beta-hydroxycholesterol--increased in erythrocyte membranes of rats with Shvetz experimental leukosis. At the same time, osmotic stability of erythrocytes and a pattern of acidic erythrogramms were altered. After UV irradiation of rats amount of cholesterol was increased as well as other unidentified substances appeared in erythrocyte membranes. These alterations appear to be one of factors responsible for development of body resistance to leukosis.