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1.
Photochem Photobiol ; 95(3): 901-908, 2019 05.
Artículo en Inglés | MEDLINE | ID: mdl-30403296

RESUMEN

The proherbicide Isoxaflutole (IXF) hydrolyzes spontaneously to diketonitrile (DKN) a phytotoxic compound with herbicidal activity. In this work, the sensitized degradation of IXF using Riboflavin (Rf), a typical environmentally friendly sensitizer, Fenton and photo-Fenton processes has been studied. The results indicate that only the photo-Fenton process produces a significant degradation of the IXF. Photolysis experiments of IXF sensitized by Riboflavin is not a meaningful process, IXF quenches the Rf excited triplet (3 Rf*) state with a quenching rate constant of 1.5 · 107  m-1  s-1 and no reaction is observed with the species O2 (1 Δg ) or O 2 · - generated from 3 Rf*. The Fenton reaction produces no changes in the IXF concentration. While the photo-Fenton process of the IXF, under typical conditions, it produces a degradation of 99% and a mineralization to CO2 and H2 O of 88%. A rate constant value of 1.0 × 109  m-1  s-1 was determined for the reaction between IXF and HO˙. The photo-Fenton process degradation products were identified by UHPLC-MS/MS analysis.


Asunto(s)
Herbicidas/química , Isoxazoles/química , Procesos Fotoquímicos , Fármacos Fotosensibilizantes/química , Riboflavina/química , Cinética , Luz
2.
J Photochem Photobiol B ; 135: 48-54, 2014 Jun 05.
Artículo en Inglés | MEDLINE | ID: mdl-24796645

RESUMEN

Kinetic and mechanistic aspects of the photochemical and microbiological degradation of the herbicide Maleic Hydrazide (MH) have been studied. Riboflavin (Rf, vitamin B2) was employed as a main photosensitizer whereas Humic Acid (HA) was included as a second sensitizer in order to more closely simulate natural environmental conditions. MH quenches excited singlet and triplet states of Rf, with rate constants close to the diffusion limit. The herbicide and dissolved molecular oxygen competitively quench triplet excited Rf. As a consequence the reactive oxygen species (ROS), superoxide radical anion (O2(-·)), hydrogen peroxide (H2O2) and singlet molecular oxygen (O2((1)Δg)) are produced by electron- and energy-transfer processes, respectively, as demonstrated by auxiliary experiments employing selective auxiliary quenchers and the exclusive O2((1)Δg) generator Rose Bengal (RB). As a global result, the photodegradation of Rf is retarded, whereas MH is degraded by the generated ROS. The bacteria Pseudomonas aeruginosa (Ps) and Bacillus subtilis (Bs), recognized as contaminants surface-water and soil and microbial antagonists of phytopathogenic, were used in the microbiological experiments. Results of the individual incubation of both bacteria in in the presence of MH indicate a stimulation on the Ps growth, implying the biodegradation of the herbicide, whereas MH only exerted a bacteriostatic effect on Bs.


Asunto(s)
Bacillus subtilis/metabolismo , Herbicidas/química , Herbicidas/metabolismo , Hidrazida Maleica/química , Fotólisis , Pseudomonas aeruginosa/metabolismo , Biodegradación Ambiental , Electrones , Contaminantes Ambientales/química , Contaminantes Ambientales/aislamiento & purificación , Contaminantes Ambientales/metabolismo , Herbicidas/aislamiento & purificación , Sustancias Húmicas , Cinética , Fármacos Fotosensibilizantes/química , Especies Reactivas de Oxígeno/química , Riboflavina/química
3.
Photochem Photobiol ; 89(6): 1463-70, 2013.
Artículo en Inglés | MEDLINE | ID: mdl-23789718

RESUMEN

Diflunisal (DFNS) and Indomethacin (IMTC) are two profusely employed NSAIDs that provide anti-inflammatory and analgesic effects in humans. The scavenging of reactive oxygen species (ROS) by both NSAIDs was systematically studied in pH 7 aqueous solution. The ROS O2 ((1)Δg), O2(•-) and H2O2, generated by visible light irradiation of Riboflavin (Rf) in the presence of DFNS and IMTC, are deactivated by the NSAIDs. The ROS scavenging action by both NSAIDs constitutes an interesting result and adds one more positive aspect to the beneficial actions attributed to these drugs. Nevertheless it should be taken into account that several NSAIDs, in particular IMTC, have been connected to the pathogenesis of gastric mucosal lesions, which in some cases includes ROS generating-ability. DFNS quenches ROS in a dominant physical fashion. It constitutes an excellent protective-antioxidant provided that is practically not destroyed/oxidized after the ROS scavenging action. IMTC, being also an efficient interceptor of ROS, belong to the so-called group of sacrificial-ROS quenchers: It is easily degraded by the oxidative species in the scavenging action. Although this property is negative in the context of prolonged ROS elimination, exhibits a promissory aspect for the degradation of pharmaceutical contaminants, such as NSAIDs, in waste waters.


Asunto(s)
Antiinflamatorios no Esteroideos/química , Diflunisal/química , Indometacina/química , Especies Reactivas de Oxígeno/química
4.
J Hazard Mater ; 186(1): 466-72, 2011 Feb 15.
Artículo en Inglés | MEDLINE | ID: mdl-21130569

RESUMEN

Within the context of environmentally friendly methods for the elimination of surface-water pollutants, the photodegradation of the phenolic pesticides bromoxynil (BXN) and dichlorophen (DCP) under simulated natural conditions has been studied. The work was done in the presence of the visible-light absorber photosensitizer riboflavin (Rf), usually present in trace quantities in natural waters. Under aerobic conditions, an efficient photooxidation of both pesticides was observed. The relatively intricate photochemical mechanism involves pesticide and oxygen consumption and, to a lesser extent, Rf degradation. The kinetic and mechanistic study supports that both H(2)O(2) and singlet molecular oxygen, O(2)((1)Δ(g)), are involved in the process. Kinetic data for the O(2)((1)Δ(g))-mediated oxidation indicate that BXN and DCP are photodegraded with this species faster than the parent compound phenol, very frequently employed as a model for aquatic contaminants, likely due to their lower pK(a) values. This observation allows the design of phenolic pesticides with different photodegradation rates under environmental conditions.


Asunto(s)
Diclorofeno/química , Nitrilos/química , Plaguicidas/química , Fenoles/química , Cinética , Oxígeno/química , Fotoquímica , Análisis Espectral/métodos
5.
J Agric Food Chem ; 56(16): 7355-9, 2008 Aug 27.
Artículo en Inglés | MEDLINE | ID: mdl-18642837

RESUMEN

The acaricide abamectin is a mixture of two colorless homologues in a molar ratio of at least 4:1 with the same structure of macrocyclic lactone. The kinetics of its degradation under direct (254 nm) and dye-sensitized (>400 nm) photoirradiation in methanol solution has been studied by UV-vis spectrophotometry, potentiometric detection of dissolved oxygen, stationary fluorescence, laser flash photolysis, and time-resolved detection of singlet molecular oxygen (O2((1)Delta(g))) phosphorescence. The results indicate that the degradation is very efficient under direct irradiation with UV light (254 nm), with a quantum yield of 0.23. On the contrary, under visible-light irradiation, using the natural pigment riboflavin or the synthetic dye rose bengal as sensitizers, the degradation is very inefficient and proceeds through a O2((1)Delta(g))-mediated mechanism, with a bimolecular rate constant for the overall O2((1)Delta(g)) quenching (the sum of physical and chemical quenching) of 5.5 x 10(5) M(-1) s(-1). This value is similar to those reported for the rate constants of the reactions of O2((1)Delta(g)) with isolated double bonds or conjugated dienes and points to similar processes in the case of abamectin.


Asunto(s)
Antihelmínticos/química , Ivermectina/análogos & derivados , Luz , Ivermectina/química , Cinética , Oxidación-Reducción , Oxígeno/química , Fotoquímica , Fotólisis , Rosa Bengala , Espectrofotometría Ultravioleta , Rayos Ultravioleta
6.
Chemosphere ; 65(2): 237-44, 2006 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-16643984

RESUMEN

The present work studies the visible-light-promoted photodegradation of the colorless fungicide carbendazim (methyl 2-benzimidazolecarbamate) and several 2-substituted benzimidazoles (SBZ's), in water or water-methanol solution, in the presence of air and, as a photosensitizer, the synthetic xanthene dye Rose Bengal (RB) or the natural pigment riboflavin (Rf). The results indicate that the degradation of each particular SBZ depends on its chemical structure and on the sensitizer employed. In the presence of RB, the degradation always operates via a singlet molecular oxygen (O(2)((1)Delta(g)))-mediated mechanism, through a highly efficient process, as deduced from the comparison of the rate constants for physical and chemical quenching of O(2)((1)Delta(g)). In the presence of Rf, the visible-light irradiation of any of the studied SBZ's produces a series of competitive processes that depend on the relative concentrations of Rf and SBZ. These processes include the quenching of excited singlet and triplet Rf states by the SBZ and the generation of both O(2)((1)Delta(g)) and superoxide radical anion (O(2)(-)), the latter generated by electron transfer from excited Rf species to the dissolved oxygen. The overall result is the photodegradation of the SBZ and the photoprotection of the sensitizer.


Asunto(s)
Colorantes/química , Fungicidas Industriales/metabolismo , Fotólisis , Fármacos Fotosensibilizantes/metabolismo , Aire , Bencimidazoles/metabolismo , Bencimidazoles/farmacología , Carbamatos/metabolismo , Carbamatos/farmacología , Fungicidas Industriales/farmacología , Metanol/química , Oxígeno/química , Fotoquímica , Fármacos Fotosensibilizantes/farmacología , Riboflavina/química , Rosa Bengala/química , Espectrofotometría , Superóxidos/química , Agua/química , Xantenos/química
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