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1.
Biomed Opt Express ; 11(12): 7032-7052, 2020 Dec 01.
Artículo en Inglés | MEDLINE | ID: mdl-33408978

RESUMEN

We report on a novel endomicroscope, to the best of our knowledge, designed for achieving full 4×4 Mueller polarimetric images of biological tissues through a fiber endoscope for medical diagnosis. The polarimetric technique is based on a previously published two-wavelength differential method (TWDM). A key component of the endomicroscope is a resonant fiber-based microprobe including a highly-selective fiber Bragg grating (FBG), free of detrimental polarimetric effects, photo written in the core of the fiber, near the output face. By means of the TWDM, and using the specially designed microprobe (diameter 2.9 mm, length 30 mm), full Mueller images of 250×250 pixels were produced at the rate of 1 image/2 s through a 2 m single mode fiber, paving the way to in vivo applications in polarimetric endomicroscopy.

2.
Light Sci Appl ; 6(2): e16208, 2017 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-30167228

RESUMEN

Propagation of light in multimode optical fibers usually gives a spatial and temporal randomization of the transmitted field similar to the propagation through scattering media. Randomization still applies when scattering or multimode propagation occurs in gain media. We demonstrate that appropriate structuration of the input beam wavefront can shape the light amplified by a rare-earth-doped multimode fiber. Profiling of the wavefront was achieved by a deformable mirror in combination with an iterative optimization process. We present experimental results and simulations showing the shaping of a single sharp spot at different places in the output cross-section of an ytterbium-doped fiber amplifier. Cleaning and narrowing of the amplifier far-field pattern was realized as well. Tailoring the wavefront to shape the amplified light can also serve to improve the effective gain. The shaping approach still works under gain saturation, showing the robustness of the method. Modeling and experiments attest that the shaping is effective even with a highly multimode fiber amplifier carrying up to 127 modes.

3.
Opt Lett ; 41(21): 5007-5010, 2016 Nov 01.
Artículo en Inglés | MEDLINE | ID: mdl-27805671

RESUMEN

A supercontinuum laser source was designed for multiplex-coherent anti-Stokes Raman scattering spectroscopy. This source was based on the use of a germanium-doped standard optical fiber with a zero dispersion wavelength at 1600 nm and pumped at 1064 nm. We analyzed the nonlinear spectro-temporal interrelations of a subnanosecond pulse propagating in a normal dispersion regime in the presence of a multiple Raman cascading process and strong conversion. The multiple Raman orders permitted the generation of a high-power flat spectrum with a specific nonlinear dynamics that can open the way to subnanosecond time-coded multiplex CARS systems.

4.
J Biomed Opt ; 21(7): 71106, 2016 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-26848782

RESUMEN

This paper reports a technique based on spectrally differential measurement for determining the full Mueller matrix of a biological sample through an optical fiber. In this technique, two close wavelengths were used simultaneously, one for characterizing the fiber and the other for characterizing the assembly of fiber and sample. The characteristics of the fiber measured at one wavelength were used to decouple its contribution from the measurement on the assembly of fiber and sample and then to extract sample Mueller matrix at the second wavelength. The proof of concept was experimentally validated by measuring polarimetric parameters of various calibrated optical components through the optical fiber. Then, polarimetric images of histological cuts of human colon tissues were measured, and retardance, diattenuation, and orientation of the main axes of fibrillar regions were displayed. Finally, these images were successfully compared with images obtained by a free space Mueller microscope. As the reported method does not use any moving component, it offers attractive integration possibilities with an endoscopic probe.


Asunto(s)
Endoscopía/instrumentación , Endoscopía/métodos , Imagen Óptica/instrumentación , Imagen Óptica/métodos , Colon/anatomía & histología , Colon/química , Humanos , Fibras Ópticas
5.
Opt Express ; 23(12): 16439-48, 2015 Jun 15.
Artículo en Inglés | MEDLINE | ID: mdl-26193615

RESUMEN

We report a novel technique for polarimetric characterization of samples through a flexible fiber endoscope, with a single shot measurement per pixel. The sample is simultaneously probed with a large diversity of polarization states, and both degree of polarization and linear retardance are determined thanks to specific processing of data. The probe polarization states are spectrally encoded on the 10 nm bandwidth of the source. The key component of the endoscope is a 3 m long specially designed optical fiber which consists of the optimized concatenation of highly birefringent fiber pieces. For a proof of principle, different calibrated or manufactured samples were successfully characterized. The proposed technique is attractive in view of reducing the measurement time of polarimetric images, in endoscopic applications.

6.
Opt Express ; 23(3): 3047-54, 2015 Feb 09.
Artículo en Inglés | MEDLINE | ID: mdl-25836165

RESUMEN

A novel technique to measure the full 4 × 4 Mueller matrix of a sample through an optical fiber is proposed, opening the way for endoscopic applications of Mueller polarimetry for biomedical diagnosis. The technique is based on two subsequent Mueller matrices measurements: one for characterizing the fiber only, and another for the assembly of fiber and sample. From this differential measurement, we proved theoretically that the polarimetric properties of the sample can be deduced. The proof of principle was experimentally validated by measuring various polarimetric parameters of known optical components. Images of manufactured and biological samples acquired by using this approach are also presented.

7.
Opt Express ; 20(5): 5524-9, 2012 Feb 27.
Artículo en Inglés | MEDLINE | ID: mdl-22418358

RESUMEN

We present a novel Q-switched laser source using a micro-optical-electromechanical mirror (MOEM) designed for short pulse emission. It is based on a hybrid configuration including a passively Q-switched microchip laser coupled to a fiber cavity closed by a cantilever type MOEM acting as an active modulator. This specially designed mirror with a single reflecting gold membrane is switched by low bias voltage ~50 V (peak to peak). This device emits pulses at tunable repetition rates up to 1.6 kHz, with ~564 ps duration and 3.4 kW peak power, which constitutes the shortest pulse duration ever reported with MOEMs based pulsed lasers.


Asunto(s)
Rayos Láser , Lentes , Sistemas Microelectromecánicos/instrumentación , Procesamiento de Señales Asistido por Computador/instrumentación , Diseño de Equipo , Análisis de Falla de Equipo
8.
Opt Express ; 20(2): 1202-12, 2012 Jan 16.
Artículo en Inglés | MEDLINE | ID: mdl-22274464

RESUMEN

We present a novel broadband laser source based on a dual cavity in which a subnanosecond passively Q-switched microchip laser is coupled with a long cavity including an acousto-optic modulator (AOM) and a microstructured optical fiber working as a non linear medium. This active-passive Q-switched laser source emits pulses as short as those emitted by the free running microchip laser (~600 ps). The time pulse emission is governed by the AOM allowing tunable repetition rate from 0 to more than 4 kHz with a temporal jitter reduced to less than 50 ns, i.e. a 600-fold reduction compared to that of the free running microchip. Furthermore, thanks to spectral broadening in the microstructured fiber, this source emits a supercontinuum from 700 nm to 1700 nm.


Asunto(s)
Citometría de Flujo/instrumentación , Dispositivos Laboratorio en un Chip , Rayos Láser , Óptica y Fotónica/instrumentación , Acústica/instrumentación , Diseño de Equipo , Materiales Manufacturados , Miniaturización , Modelos Teóricos
9.
Opt Lett ; 34(21): 3409-11, 2009 Nov 01.
Artículo en Inglés | MEDLINE | ID: mdl-19881610

RESUMEN

Polarization images were obtained using a flexible optical fiber device. The endoscopic technique is based on the real-time compensation of the birefringence of the standard fiber by means of a miniaturized Faraday rotator. Based on a Jones formalism analysis, specific signal processing allows one to extract both the phase retardation and the degree of polarization of the light backscattered by a remote target.

10.
Opt Lett ; 34(14): 2087-9, 2009 Jul 15.
Artículo en Inglés | MEDLINE | ID: mdl-19823510

RESUMEN

Taking advantage of the combination of stimulated Raman scattering and nonlinear polarization rotation in a single-mode optical fiber, a temporal reshaping of subnanosecond pulses is achieved by means of both spectral and polarization filtering. Shortening of 650 ps down to 43 ps temporally and spectrally stable pulses is experimentally obtained. Numerical simulations supporting this new temporal filtering are presented.


Asunto(s)
Algoritmos , Diseño Asistido por Computadora , Modelos Teóricos , Fibras Ópticas , Procesamiento de Señales Asistido por Computador/instrumentación , Espectrometría Raman/instrumentación , Simulación por Computador , Diseño de Equipo , Análisis de Falla de Equipo , Luz , Dispersión de Radiación
11.
Opt Express ; 16(23): 19018-33, 2008 Nov 10.
Artículo en Inglés | MEDLINE | ID: mdl-19581994

RESUMEN

We demonstrate that the resonance wavelength of fiber Bragg gratings photowritten in the core of microstructured optical fibers can be efficiently stabilized versus temperature by inserting suitable refractive index materials with a negative thermal sensitivity into the holes. By these means, the effective index of the guided mode undergoes thermal variations which counterbalance the effect of the grating period thermal drift. The residual excursion of the resonance wavelength can be limited to less than +/- 10 pm over a 70 degrees C range of temperature into Microstructured Optical Fibers (MOFs) having realistic geometrical parameters, and using existing refractive index materials. Low cost passively stabilized reflectors with insertion loss lower than 0.3 dB can be realized by splicing single mode fibers at both ends of a short length of a filled MOF including the fiber Bragg grating.


Asunto(s)
Fibras Ópticas , Fotoquímica/métodos , Refractometría/instrumentación , Diseño Asistido por Computadora , Diseño de Equipo , Análisis de Falla de Equipo , Reproducibilidad de los Resultados , Sensibilidad y Especificidad , Temperatura
12.
Opt Lett ; 32(16): 2390-2, 2007 Aug 15.
Artículo en Inglés | MEDLINE | ID: mdl-17700795

RESUMEN

We present a photosensitive three-hole microstructured optical fiber specifically designed to improve the refractive index sensitivity of a standard fiber Bragg grating (FBG) sensor photowritten in the suspended Ge-doped silica core. We describe the specific photowriting procedure used to realize gratings in such a fiber. We then determine their spectral sensitivity to the refractive index changes of material filling the holes surrounding the core. The sensitivity is compared with that of standard FBGs photowritten in a six-hole fiber with a larger core diameter. We demonstrate an improvement in the sensitivity by two orders of magnitude and reach a resolution of 3 x 10(-5) and 6 x 10(-6) around mean refractive index values of 1.33 and 1.40, respectively.

13.
Opt Lett ; 31(12): 1779-81, 2006 Jun 15.
Artículo en Inglés | MEDLINE | ID: mdl-16729068

RESUMEN

A simple self-referenced nondestructive method is proposed for measuring the cutoff wavelength of microstructured optical fibers (MOFs). It is based on the analysis of the time-dependent optical power transmitted through a bow-tie slit rotating in the far-field pattern of the fiber under test. As a first demonstration, the cutoff wavelength of a 2 m MOF sample is found to be close to that provided by numerical predictions (approximately 25 nm higher). Because of the high dynamics of the measurement, the uncertainty is limited to Dlambda= +/-10 nm.

14.
Opt Express ; 14(22): 10359-70, 2006 Oct 30.
Artículo en Inglés | MEDLINE | ID: mdl-19529434

RESUMEN

We report what we believe to be the first Tilted short-period Fiber Bragg Grating photowritten in a microstructured optical fiber for refractive index measurement. We investigate the spectral sensitivity of Tilted Fiber Bragg Grating to refractive index liquid inserted into the holes of a multimode microstructured fiber. We measure the wavelength shift of the first four modes experimentally observed when calibrated oils are inserted into the fiber holes, and thus we determine the refractive index resolution for each of these modes. Moreover, a cross comparison between experimental and simulation results of a modal analysis is performed. Two simulation tools are used, respectively based on the localized functions method and on a finite element method. All results are in very good agreement.

15.
Opt Express ; 14(22): 10865-77, 2006 Oct 30.
Artículo en Inglés | MEDLINE | ID: mdl-19529499

RESUMEN

A theoretical study of optimized single mode Er-doped MOFs designed for high efficiency amplification at 1550nm is carried out, deriving benefit from the demonstrated very low decrease of the overlap factor versus wavelength. In spite of this potential advantage, classical single mode MOFs are first shown to be less efficient than usual Er-doped step index fibers (SIF). However, novel single mode large core MOFs (LCMOFs) are designed, providing overlap factors higher than 0.9 at both the pump and the signal wavelengths. To obtain the same gain, the necessary length of LCMOF is reduced by up to 40% compared to that of Er-doped SIF. Such a highly efficient amplifying fiber is attractive for short pulse and soliton amplification.

16.
Opt Lett ; 30(15): 1962-4, 2005 Aug 01.
Artículo en Inglés | MEDLINE | ID: mdl-16092233

RESUMEN

Coherent combining is demonstrated in a clad-pumped Yb-doped double-core fiber laser. A slope efficiency of more than 70% is achieved with 96% of the total output power in the fundamental mode of one of the two cores. This high combining efficiency is obtained when both cores are coupled via a biconical fused taper in a Michelson interferometer configuration.

17.
Opt Lett ; 29(1): 38-40, 2004 Jan 01.
Artículo en Inglés | MEDLINE | ID: mdl-14719653

RESUMEN

We report what is to our knowledge the first characterization at high temperatures of long-period fiber gratings written in Ge-free air-silica microstructure fiber. The gratings written with the electric-arc technique suffer a low shift of the resonance wavelengths when the temperature is increased from 20 degrees C to 1200 degrees C. This shift is studied and compared with that of a long-period fiber grating written in a standard single-mode fiber by the same technique. Good thermal stability of the grating and of the fiber after annealing at 1200 degrees C for 1 h is demonstrated.

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