RESUMEN
We present the case of a 66-year-old woman with intermittent dysphagia and esophageal food impaction. The endoscopic examination showed an upper and middle esophagus with a diffuse circumferential, white, crackleware epithelium. Esophageal biopsies revealed acanthosis and papillomatosis with diffuse hyperkeratosis. High dose of Proton pump inhibitors was initiated with improvement of all symptoms 6 weeks later.
Asunto(s)
Reflujo Gastroesofágico , Anciano , Biopsia , Endoscopía , Femenino , Reflujo Gastroesofágico/complicaciones , Reflujo Gastroesofágico/diagnóstico , Reflujo Gastroesofágico/tratamiento farmacológico , Humanos , Inhibidores de la Bomba de Protones/uso terapéuticoAsunto(s)
Enfermedad de Crohn , Sarcoidosis , Anticuerpos Monoclonales/efectos adversos , Enfermedad de Crohn/tratamiento farmacológico , Fármacos Gastrointestinales/efectos adversos , Humanos , Infliximab/efectos adversos , Sarcoidosis/inducido químicamente , Sarcoidosis/diagnóstico , Resultado del TratamientoRESUMEN
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Asunto(s)
Humanos , Masculino , Persona de Mediana Edad , Metronidazol/uso terapéutico , Infecciones por Spirochaetales/complicaciones , Enfermedades Intestinales/tratamiento farmacológico , Enfermedades Intestinales/microbiología , Diarrea/microbiología , Dolor Abdominal/etiologíaRESUMEN
The intestinal spirochaetosis is defined as the presence of spirochetes on the colonic surface. We present the case of a 57-years-old male, with a history of 4-5 months of diffuse abdominal pain, watery diarrhoea due to this infection. The colonoscopy revealed a serpiginous ulcer in the cecum. The biopsy was positive for intestinal spirochaetosis. It is rare infection, more common among immunocompromised patients and HIV, with a faecal-oral transmission. Most cases are incidental findings in the endoscopic screening. In symptomatic patients the watery diarrhoea and non-specific abdominal pain are the most common symptoms. The macroscopic appearance on the colonoscopy is often normal or non-specific lesions can be identified. The diagnosis is based on the biopsy with haematoxylin and eosin and the confirmation can be made with a Warthin-Starry stain. In symptomatic patients the metronidazole is the preferred treatment option. Although it is rare infection, clinicians should be aware of it in patients with common gastrointestinal symptoms.