RESUMEN

INTRODUCTION: Intestinal obstruction as a result of congenital peritoneal bands is rare in surgical practice. It typically compromises the small bowel, and it also has been reported to involve the appendix or a Meckel's diverticulum. However, peritonealized urachal remnant as part of a congenital band is highly infrequent. CASE REPORT: 5-year-old boy presenting with intestinal obstruction related to a peritoneal band from the mesentery to the appendix and a peritonealized urachal remnant, associated with an incidental finding of a Meckel's diverticulum. Diagnosis was achieved laparoscopically. The peritoneal band, the urachal remnant, and the Meckel's diverticulum were resected. DISCUSSION: Kerkeni's congenital band classification consists of 4 independent groups. This case combines both a band stemming from an embryological remnant and an idiopathic band.

INTRODUCCION: La obstrucción intestinal por bandas peritoneales congénitas es poco común en la práctica quirúrgica. Su ubicación más frecuente compromete el intestino delgado y existen reportes que involucran el apéndice y el divertículo de Meckel, pero que un remanente uracal peritonizado haga parte de una banda congénita es verdaderamente singular. CASO CLINICO: Niño de 5 años de edad con cuadro de obstrucción intestinal en el que confluyen una banda peritoneal, que va del mesenterio al apéndice y que se une a un remanente uracal peritonizado, asociado al hallazgo incidental de un divertículo de Meckel. El diagnóstico se definió por medio de una laparoscopia y como tratamiento se realizó la resección de la banda peritoneal, del remanente uracal y del divertículo de Meckel. DISCUSION: La clasificación de bandas congénitas de Kerkeni comprende 4 grupos independientes, en este caso confluyen una banda derivada de un remanente embriológico junto con el tipo idiopático.

Asunto(s)

RESUMEN

Introducción: La obstrucción intestinal por bandas peritoneales con-génitas es poco común en la práctica quirúrgica. Su ubicación más fre-cuente compromete el intestino delgado y existen reportes que involucranel apéndice y el divertículo de Meckel, pero que un remanente uracal pe-ritonizado haga parte de una banda congénita es verdaderamente singular.Caso clínico: Niño de cinco años de edad con cuadro de obstruc-ción intestinal en el que confluyen una banda peritoneal, que va delmesenterio al apéndice y que se une a un remanente uracal peritonizado,asociado al hallazgo incidental de un divertículo de Meckel. El diag-nóstico se definió por medio de una laparoscopia y como tratamientose realizó la resección de la banda peritoneal, del remanente uracal ydel divertículo de Meckel.Discusión: La clasificación de bandas congénitas de Kerkenicomprende 4 grupos independientes, en este caso confluyen una bandaderivada de un remanente embriológico junto con el tipo idiopático.

Introduction. Intestinal obstruction as a result of congenital peri-toneal bands is rare in surgical practice. It typically compromises thesmall bowel, and it also has been reported to involve the appendix ora Meckel’s diverticulum. However, peritonealized urachal remnant aspart of a congenital band is highly infrequent.Case report: 5-year-old boy presenting with intestinal obstructionrelated to a peritoneal band from the mesentery to the appendix and aperitonealized urachal remnant, associated with an incidental findingof a Meckel’s diverticulum. Diagnosis was achieved laparoscopically.The peritoneal band, the urachal remnant, and the Meckel’s diverticulumwere resected.Discussion: Kerkeni’s congenital band classification consists of 4independent groups. This case combines both a band stemming froman embryological remnant and an idiopathic band.

Asunto(s)

RESUMEN

Dyslipidemias are a group of diseases, which are characterized by abnormal blood concentrations of cholesterol, triglycerides and/or low-density lipoprotein-cholesterol (LDL-c). Dyslipidemia is a determinant condition for the progress of an atherosclerotic plaque formation. The resulting atherogenicity is due to at least two mechanisms: first, to the accumulation in the plasma of lipid particles that have the capacity to alter the function of the endothelium and deposit at the atheromatous plaque, and second, at an insufficient concentration of multifactorial type of high density lipoprotein-cholesterol (HDL-c), whose function is to protect against the development of atherosclerosis. Its highest prevalence is encountered among individuals with diabetes, hypertension or overweight. Hyperlipidemia is one of the main predisposing factors for the development of cardiovascular disease. Hyperlipidemia can be the result of a genetic condition, the secondary expression of a primary process or the consequence of exogenous factors (food, cultural, socio-economic, etc.), all of which lead to the elevation of plasma lipid levels. The objective of this study was to carry out an analysis of the genes involved in the development of dyslipidemias that lead to cardiovascular disease with special emphasis on the proprotein convertase subtilin/kexin type 9 (PCSK9) gene. The PCSK9 gene participates in the development of primary dyslipidemias, mainly familial hypercholesterolemia, currently the pharmacological treatment of choice to reduce LDL-c are statins, however, it has been observed that these have been insufficient to eliminate cardiovascular risk, especially in subjects with primary forms of hypercholesterolemia related to genetic mutations, or statin intolerance.

RESUMEN

En la actualidad, la sofisticación de la tecnología en el sector sanitario ofrece ventajas para el diagnóstico y tratamiento de los pacientes; sin embargo, los riesgos y eventos adversos que acompañan a esta nueva generación de tecnología son una tendencia creciente a nivel global. Hay muchos factores que contribuyen a este escenario, especialmente el error humano que aumenta en las instituciones de salud cuando el proceso de incorporación tecnológica no incluye la adecuada formación del personal. El objetivo de este proyecto es contribuir a la seguridad de los pacientes y ofrecer servicio de calidad en la atención sanitaria. Para ello debe implementarse una estrategia de capacitación del personal en el uso adecuado de la tecnología para ofrecer un servicio responsable, comprometido y profesional.

Currently, the sophistication of technology in the health-care industry offers advantages for the diagnosis and treatment of patients; however, the risks and adverse events that go with this new generation of technology are a growing tendency worldwide. There are many factors that contribute to this scenario, but especially the increase in human error in health-care institutions when the process of technological incorporation does not include appropriate personnel training. The objective of this project is to contribute to patient safety and offer quality healthcare. In order to offer a responsible, committed, and professional service,a strategy of training personnel in the appropriate use of technology must be implemented.

Na atualidade a sofisticação da tecnologia no sector sanitário oferece vantagens para o diagnóstico e tratamento dos pacientes, no entanto, os riscos e eventos adversos que acompanham esta nova geração de tecnologias são uma tendência crescente a nível global. Existem muitos fatores que contribuem a este palco: especialmente o erro humano que aumenta nas instituições de saúde quando o processo de incorporação tecnológica não inclui a adequada formação do pessoal. O objetivo deste projeto é contribuir à segurança dos pacientes e oferecer atenção de qualidade na atenção sanitária, a implementação de uma estratégia de capacitação do pessoal no uso adequado da tecnologia para oferecer um serviço responsável, comprometido e profissional.

RESUMEN

Lectins participate in the immune mechanisms of crustaceans. They have been considered as humoral receptors for pathogen-associated molecular patterns; however, some reports suggest that lectins could regulate crustacean cellular functions. In the present study, we purified and characterized a serum lectin (CqL) from the hemolymph of Cherax quadricarinatus by affinity chromatography and determined its participation in the regulation of hemocytes' oxidative burst. CqL is a 290-kDa lectin in native form, constituted by 108, 80, and 29-kDa subunits. It is mainly composed of glycine, alanine, and a minor proportion of methionine and histidine. It showed no carbohydrates in its structure. CqL is composed of several isoforms, as determined by 2D-electrophoresis, and shows no homology with any crustacean protein as determined by Lc/Ms mass spectrometry. CqL agglutinated mainly rat and rabbit erythrocytes and showed a broad specificity for monosaccharides such as galactose, glucose, and sialic acid, as well as for glycoproteins, such as porcine stomach and bovine submaxillary mucin and fetuin. It is a Mn(2+)-dependent lectin. CqL recognized 8% of crayfish granular hemocytes and increased 4.2-fold the production of hemocytes' superoxide anion in vitro assays when compared with non-treated hemocytes. This effect showed the same specificity for carbohydrates as hemagglutination; moreover, superoxide dismutase and diphenyleneiodonium chloride were effective inhibitors of CqL oxidative-activation. The CqL homoreceptor is a 120-kDa glycoprotein identified in the hemocytes lysate. Our results suggest that CqL participates actively in the regulation of the generation of superoxide anions in hemocytes using NADPH-dependent mechanisms.

Asunto(s)

RESUMEN

Common bean (Phaseolus vulgaris L.) is an important source of dietary protein and minerals worldwide. Genes conditioning variability for mineral contents are not clearly understood. Our ultimate goal is to identify genes conditioning genetic variation for Zn and Fe content. To establish mapping populations for this objective, we tested mineral content of 29 common bean genotypes. Chemical analyses revealed significant genetic variability for seed Zn and Fe contents among the genotypes. Genetic diversity was evaluated with 49 primer pairs, of which 23 were simple sequence repeats (SSR), 16 were developed from tentative consensus (TC) sequences, and 10 were generated from common bean NBS-LRR gene sequences. The discriminatory ability of molecular markers for identifying allelic variation among genotypes was estimated by polymorphism information content (PIC) and the genetic diversity was measured from genetic similarities between genotypes. Primers developed from NBS-LRR gene sequences were highly polymorphic in both PIC values and number of alleles (0.82 and 5.3), followed by SSRs (0.56 and 3.0), and markers developed from TC (0.39 and 2.0). genetic similarity values between genotypes ranged from 14.0 (JaloEEP558 and DOR364) to 91.4 (MIB152 and MIB465). Cluster analysis clearly discriminated the genotypes into Mesoamerican and Andean gene pools. Common bean genotypes were selected to include in crossing to enhance seed Zn and Fe content based on genetic diversity and seed mineral contents of the genotypes.

RESUMEN

The bleaching of non vital teeth that is described in this article has demonstrated to give good clinical results, and because of its easy way to apply we believe that it is the option for the treatment of this teeth, as long as we have a good an realistic diagnostic considering the results we may obtain. One the selection has been made we proceed to the bleaching, the substances that we use are easily obtain, superoxol and sodium perborate. The preparation of the tooth began with the removal of any restauration or decayed tissue that is may present after this we remove the material from the pulp chamber 1 mm below the gingival margin, then clean perfectly the chamber, then we deshidrate the tubulae, then put a pellet of cotton on the vestibular wall of the chamber, put some superoxol in the cotton, heat it up, remove the cotton, put some sodium perborate and hidroge peroxide paste in the chamber and seal it with cavit, and wait from 3 to 7 days for results.

Asunto(s)

Asunto(s)