RESUMEN
A patient is reported with a form of epidermolysis bullosa, hitherto undescribed to the best of our knowledge, characterized by the slow centripetal progression of symmetrical blister formation, milia, scarring, atrophy, and nail dystrophy. Electron microscopy, immunofluorescence mapping, and KF-1 monoclonal antibody studies confirm this disease to be a form of dystrophic epidermolysis bullosa, probably of autosomal recessive transmission despite the absence of acral deformities, contractures, mucosal involvement, and growth retardation.
Asunto(s)
Cicatriz/patología , Epidermólisis Ampollosa/patología , Anticuerpos Monoclonales , Cicatriz/fisiopatología , Epidermólisis Ampollosa/fisiopatología , Femenino , Humanos , Persona de Mediana Edad , Piel/ultraestructuraRESUMEN
The study of abnormal nails (onychopathology) can contribute considerably to the art of diagnostic medicine. Nail pigmentation is an important facet of onychopathology. Pigmentation abnormalities may suggest general disease and in some cases indicate a specific diagnosis. Their recognition may also be valuable in following the side effects of treatment.
Asunto(s)
Enfermedades de la Uña/etiología , Trastornos de la Pigmentación/etiología , Humanos , Enfermedades de la Uña/diagnóstico , Examen Físico , Trastornos de la Pigmentación/diagnósticoRESUMEN
The study of abnormal nails (onychopathology) can contribute considerably to the art of diagnostic medicine. Nail pigmentation is an important facet of onychopathology. Pigmentation abnormalities may suggest general disease and in some cases indicate a specific diagnosis. Their recognition may also be valuable in following the side effects of treatment.
Asunto(s)
Enfermedades de la Uña/etiología , Trastornos de la Pigmentación/etiología , Humanos , Enfermedades de la Uña/diagnóstico , Examen Físico , Trastornos de la Pigmentación/diagnósticoRESUMEN
The nail-patella syndrome has been of interest to dermatologists because the diagnosis of this multisystem complex may be suggested simply by observing the patient's abnormal nails. It is the purpose of this article to call attention to triangular lunulae and other nail abnormalities associated with this syndrome, as well as other causes of triangular lunulae.
Asunto(s)
Síndrome de la Uña-Rótula/diagnóstico , Uñas Malformadas/diagnóstico , Adulto , Femenino , Humanos , Síndrome de la Uña-Rótula/complicaciones , Síndrome de la Uña-Rótula/genética , Uñas Malformadas/complicaciones , Psoriasis/complicacionesAsunto(s)
Dermatitis Herpetiforme/diagnóstico , Prurito/diagnóstico , Dermatosis del Cuero Cabelludo/diagnóstico , Dermatitis Herpetiforme/inmunología , Dermatitis Herpetiforme/patología , Antígenos HLA/análisis , Humanos , Inmunoglobulina A/análisis , Inmunoglobulina M/análisis , Masculino , Persona de Mediana Edad , Reticulina/inmunologíaRESUMEN
By judicious consideration of the clinical appearance, by direct examination with magnification, and by culture results, skin biopsy, and other laboratory results, the clinician is able to diagnose most pathological conditions of the scalp. The scalp participates in many systemic disorders and frequently is the chief site of involvement. Similarly, many generalized disorders limited to the skin exhibit their most typical manifestations in the scalp. Whenever a diagnosis eludes the investigator, more than likely he or she has not considered all of the etiological possibilities or has not pursued an adequate laboratory investigation. A few scalp diseases initially present nonspecific clinical pictures. By utilizing follow-up examinations at appropriate intervals, the diagnosis can eventually be made. Once a diagnosis is made, appropriate treatment will generally produce satisfactory improvement or cure. Nevertheless, a few generally rare conditions will defy the physician's most enlightened and aggressive therapy.
Asunto(s)
Dermatosis del Cuero Cabelludo/diagnóstico , Acné Queloide/diagnóstico , Adolescente , Adulto , Alopecia Areata/diagnóstico , Celulitis (Flemón)/diagnóstico , Niño , Preescolar , Dermatitis Herpetiforme/diagnóstico , Dermatitis por Contacto/diagnóstico , Dermatitis Seborreica/diagnóstico , Foliculitis/diagnóstico , Herpes Zóster/diagnóstico , Herpes Zóster/patología , Humanos , Infestaciones por Piojos/diagnóstico , Liquen Plano/diagnóstico , Lupus Eritematoso Discoide/diagnóstico , Neurodermatitis/diagnóstico , Pénfigo/diagnóstico , Psoriasis/diagnóstico , Piodermia/diagnóstico , Esclerodermia Localizada/diagnóstico , Tiña del Cuero Cabelludo/diagnósticoAsunto(s)
Acrodermatitis/diagnóstico , Acrodermatitis/terapia , Niño , Humanos , Masculino , Piel/patologíaAsunto(s)
Lesiones Precancerosas/diagnóstico , Enfermedades de la Piel/diagnóstico , Neoplasias Cutáneas/diagnóstico , Anciano , Diagnóstico Diferencial , Humanos , Queratosis/diagnóstico , Masculino , Lesiones Precancerosas/genética , Lesiones Precancerosas/patología , Enfermedades de la Piel/genética , Enfermedades de la Piel/patologíaRESUMEN
Swimmer's itch and seabather's eruption, while similar in morphology, differ in important aspects. Seabather's eruption occurs chiefly in salt water and involves covered parts of the body. Swimmer's itch occurs chiefly in fresh water and involves uncovered parts. The cause of swimmer's itch is definitely known to be schistosome cercariae, while the cause of seabather's eruption is for the most part unknown. Algae, coelenterates and schistosomes as well as other organisms found in seawater have been suggested. Control of swimmer's itch is best accomplished by decreasing the snail population.