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BACKGROUND: The prevalence of colorectal polyps in the general population is 10%. Hormonal alterations in acromegaly stimulates adenomatose polyps development making that increase it prevalence. Colonoscopy has elevated sensibility and specificity in detection of colorectal adenomas. OBJECTIVE: Identify colonic polyps in patients with acromegaly and establish the importance of colonoscopy as a detection method. MATERIAL AND METHODS: Retrospective, observational and descriptive study made in Colon and Rectum Surgery Department from March 2000 to March 2007 in patients with acromegaly and colonoscopy. Analyzed variables were: gender,age, endoscopy findings and histopathological results. Descriptive statistics were used to analysis of results. RESULTS: Thirty-two patients were included: 14 (44%) men, 18 (56%) women. The mean age was 48 (range 22 to 75 years old). In 9 (28%) patients were detected colorectal polyps, predominately in the sigmoid. Fifteen polyps lesion were found: 7 (46.6%) adenomas: 5 (33.3%) tubular and 2 (13.3) villous, 6 (40%) hyperplasic, 1 (6.6%) inflammatory and 1 (6.6%) carcinoma. Colonoscopy was complete in 30 (93.7%) patients. CONCLUSIONS: The prevalence of colonic polyps inpatients with acromegaly undergoing colonoscopy,was 28%, higher than expected in the general population. Colonoscopy constitutes an important diagnosis technique in early neoplasia detection.

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Pyoderma gangrenosum is one of the most severe extraintestinal manifestations in patients with ulcerative colitis (UC) and Crohn s disease. This lesion is frequently located on the lower extremities and the torso. Peristomal pyoderma gangrenosum (PPG) is extremely rare. We report the first published patient with PPG and UC in Mexico. PPG occurred six weeks after restorative proctocolectomy. Diagnosis was performed by clinical presentation and biopsy. Ulcer resolution was achieved with oral steroids and local wound care. Patient did not show any recurrence at one year follow-up. We suggest suspecting this illness in all patients with UC who had a restorative proctocolectomy and present difficult management peristomal ulcers.

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Tucumán es una provincia de Argentina con una población de 1,331,923 habitantes, más del 70 por cento de ellos es atendido por el sistema público de salud. Debido a esta situación, los servicios públicos de salud deben optimizar su organización y la administración de tecnología debe adaptarse a la misma. El objetivo de este trabajo es evaluar el estado de la Ingeniería Clínica en la provincia para implementar programas correctivos y realizar sugerencias para redefinir las políticas de salud y la administración de tecnología. El trabajo de campo de desarrolló principalmente en los 5 hospitales cabecera (principales), situados en la capital de la provincia, y en algunos centros del interior de la provincia. Los datos de los distintos servicios se recogieron insitu a través de encuestas. Solamente se consederaron aquellos equipos de mediana y alta complejidad. La información disponible se clasificó teniendo en cuenta tres parámetros: Tecnología, Calidad y Mantenimiento. También se recolectaron datos para evaluar los Recursos Humanos afectados a las tecnologías. La comparación de los datos colectados entre los diferentes servícios muestra la importancia y los beneficios obtenidos a partir de una adecuada aplicación de los conceptos y métodos de la Ingeniería Clínica. Desafortunadamente, al presente no existe ningún programa de acción coordinada tal como lo recomiendan las organizaciones internacionales

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Left ventricular volume calibration based on the conductance catheter depends on the correct determination of the parallel conductance (Gp). Baan's saline manoeuvre procedure leads to Gp by finding the end-systolic (Ges) and end-diastolic (Ged) conductances, for each beat of the dilution curve rising limb. After plotting such values in an xy-system, their linear regression is back-projected to intersect the identity line, so yielding an estimated Gp. The objective is to theoretically analyse all possible lines, Ges = aGed + b (Baan's line) and, based on experimental results, to establish their limitations. This was attained by calculating the regression lines using, first Ged = f1(Ges) and thereafter, Ges = f2(Ged), which led to two values, Gp2 and Gp1, for the parallel conductance. The morphology of the saline curve was also modified to assess its effect on the extrapolation. Multiple dilutions were recorded in eight experimental dogs injecting different concentrations. Each curve was classified according to the maximum change (VAR) reached by the total average conductance. Over 138 manoeuvres, 276 regressions were processed yielding correlations higher than 0.65. Of this total, 92.4% gave positive parallel conductances. The rest produced negative values and, thus, were neglected. If the two (Ged, Ges) statistical relationships were ideal, they should yield Gp = Gp1 = Gp2; however, there were differences which, when Gp1 was studied against Gp2, led to: Gp1 = 0.97 Gp2 + 0.055, with r = 0.9476, and n = 85. The remaining 53 were discarded because either some Gp values were negative, or the correlation of Ges which Ged (or vice versa) was < 0.85, and/or VAR < 15%; the two latter conditions were found necessary for reliable calibration. Baan's line high correlation is not a unique condition to ensure the accuracy and precision of Gp determination because the slope a depends on VAR and, thus, different intersections with the identity line may be obtained. Its recommended that manoeuvres be used with at least eight data points, with VAR > 15% and, finally, with (Ges, Ged) correlation better than 0.85. Theoretical analysis of Baan's line offers a reference frame, which contains only a limited number of practical possibilities.

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The conductance catheter has gained momentum since its introduction in cardiovascular dynamics back in 1980. However, measuring errors are still blurring its clinical acceptance. The main objective here was to study the effects of the injected saline concentration and temperature on the evaluation of the parallel conductance, Gp, and thus, on the correction volume Vp. That conductance, Gp, and its associated volume, Vp, were computed using 167 saline dilution curves obtained with boluses at different concentrations and temperatures, injected in seven anesthetized closed-chest dogs. The excursion of the total conductance relative to the steady-state value during a saline maneuver showed good correlation with the injected concentration at both studied temperatures. The reference parallel volume (one reference per dog) was defined as the average value obtained with three successive maneuvers, at 6-M concentration and at body temperature; therefore, the method acted as its own reference. The variation of Vp relative to the reference value was clearly dependent on the injected concentration and on its temperature; dispersion was greater at 22 degrees C than at 40 degrees C. The variability would recognize also other causes, such as uncertainty of the extrapolation procedure and the thoracic redistribution of electrical field lines. As conclusion, it is recommended to characterize each maneuver by its concentration and temperature. Body temperature and 6-M concentration appear as the most recommendable combination for the injectate in most animals. Finally, these results intend to characterize the Vp estimation procedure in order to minimize errors. The variability of Vp, in different experimental conditions, demonstrated that both concentration and temperature are additional parameters that may modify the Gp estimate.

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The impedancimetric method is a technique for the rapid evaluation of milk bacterial content and also of its subproducts. Several authors have made use of culture conductance changes during bacterial growth for quantitative and qualitative assessments of microbial growth. However, interface capacitance curves, Ci, have not been used. In this paper, we quantify bacteria in cow raw milk by following their growth as the above-mentioned capacitance change time course event. With it, bigger growth variations, shorter detection times and a better coefficient of correlation with the plate count method were obtained than those yielded by conductance curves. Calibration was performed by plotting initial known concentrations, IC (CFU/ml), as a function of the time detection theshold (TDT).

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One problem faced by intracardiac conductance volumetry is the non-uniform distribution of the injected current. Salo, in 1989, proposed a method to correct this undesirable effect. The objective here is to test Salo's method in known volumes of simple geometry by obtaining volume profiles. A plastic rod with 15 metallic rings simulated the conductance catheter. Five sections were used for the resistance measurements employing the upper electrode as fixed current source and the lowest one as the shifting source. This is part of Salo's procedure. The source-to-section distance was measured from the moving source to the section (linear definition) or using the equivalent distance concept (Salo's). Thereafter, each sectional resistance set of values was plotted as a function of the inverse of the source-to-section distance (either definition) elevated to an empirical exponent k to obtain the corrected sectional resistance by extrapolation back to zero of the regression line, i.e., a value produced by a source theoretically placed at infinity. In addition, a mathematical analysis was attempted, searching for an optimum k based on minimum volume error. The best volume profiles for two cylinders and a frustum were obtained with k = 2 using the linear definition of distance (errors of -3.49%, -1.25% and -3.65%, respectively). Moreover, the frustum angle was determined within 0.4 degrees (2.7%) of the real value. The theoretical analysis led to an inverse logarithmic relationship between the exponent k and the source-to-section distance.(ABSTRACT TRUNCATED AT 250 WORDS)

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