RESUMEN

Peculiarities of mitotic regime and expression of proliferating cell nuclear antigen were investigated in 18 polyps and 35 cases of colorectal cancer. Direct relationship between spectrum and degree of manifestation of proliferative activity, level of morphological malignant tumors and accumulation of oncopathology in the patient pedigrees was established.

Asunto(s)

Poliposis Adenomatosa del Colon/patología , Neoplasias Colorrectales/patología , Mucosa Intestinal/patología , Intestino Grueso/patología , Poliposis Adenomatosa del Colon/genética , Adulto , Anciano , Biomarcadores de Tumor , División Celular , Femenino , Humanos , Inmunohistoquímica , Masculino , Persona de Mediana Edad , Índice Mitótico , Linaje , Antígeno Nuclear de Célula en Proliferación/análisis