RESUMEN
The first occurrence of "Hyena disease" in cattle in Finland is described. The affected beef bulls consumed very high doses of vitamins A, D and E. Some of them developed to "Hyena" bulls and some to "Hyena/dwarf"-bulls. The radiological signs in the skeleton were similar to those which can occur in connection with vitamin A and D overdoses.
Asunto(s)
Enfermedades Óseas/veterinaria , Enfermedades de los Bovinos/inducido químicamente , Hipervitaminosis A/veterinaria , Vitamina D/envenenamiento , Vitamina E/envenenamiento , Animales , Enfermedades Óseas/inducido químicamente , Huesos/diagnóstico por imagen , Bovinos , Finlandia , Masculino , RadiografíaRESUMEN
Effects of graded intensity exercise on plasma lipids was studied in Standardbred and Finnishbred Trotters. The rate of lipolysis indicated by the elevated plasma concentrations of glycerol increased parallel with the intensity of the trot in the Standardbreds, but not as clearly in the Finnishbred trotters. During the exercise plasma triglyceride concentration increased significantly and the increase correlated with the intensity of the exercise as well as the activity of lipolysis. Together with the increase in plasma triglycerides, there was a parallel increase in the pre-beta fraction of lipoproteins which suggests that the hepatic synthesis of triglycerides was increased. It was calculated that about one third of the nonesterified fatty acids released in lipolysis during the high-intensity exercise is oxidized and the remainder is used for resynthesis of triglycerides. Since there were interstrain differences in the concentrations of triglycerides and glycerol after the high-intensity exercise it is suggested that the differences may be of some value in the estimation of recovery after submaximal exercise.
Asunto(s)
Enfermedades de los Caballos/etiología , Hiperlipidemias/veterinaria , Esfuerzo Físico , Animales , Ácidos Grasos no Esterificados/sangre , Glicerol/sangre , Caballos , Hiperlipidemias/etiología , Triglicéridos/sangreRESUMEN
Previous studies in humans have shown that alanine is released from the skeletal muscle in proportion to the work load. We have measured plasma alanine and urea concentrations in well-trained Standardbred and Finnish-bred (cold-blooded) trotters after a graded-intensity exercise and during recovery to study metabolic responses to exercise in this animal model. As controls we measured blood lactate, pyruvate, and glucose concentrations as well as hematocrit values. Metabolic responses to exercise were closely reflected in all these parameters. Plasma alanine increased relatively more than plasma lactate at moderate-intensity exercise near anaerobic threshold. The linear correlation between the intensity of exercise and plasma alanine was similar to that observed earlier in humans. Interestingly, plasma alanine concentrations remained elevated long after the submaximal exercise, whereas the concentration of lactate, pyruvate, and glucose decreased more rapidly. No significant changes were found in plasma urea concentration under these conditions. The most significant differences in the metabolic responses to exercise of the two breeds studied were the higher lactate-to-pyruvate ratios achieved during the high-intensity exercise and the more sensitive increases of plasma alanine even during low-intensity exercise in the Finnish-bred horses. These differences probably reflect different compositions of muscle fiber types in the two breeds. The findings together indicate that plasma alanine is greatly increased in the racehorse during and after a high-intensity exercise and thus is an important vehicle in transporting ammonia and carbon skeletons of products of anaerobic glycolysis out of the muscle tissue.