RESUMEN
Five hinokitiol-related compounds (hinokitiol (beta-thujaplicin), beta-dolabrin, gamma-thujaplicin, 4-acetyltropolone and alpha -thujaplicin) isolated from the acid oil of Aomori Hiba (Thujopsis dolabrata Sieb. et Zucc. var hondai MAKINO) showed clear antifungal activity against wood-rotting fungi. These compounds have obvious insecticidal effects on termites. They also exhibited potent acaricidal activity against mites. The above-mentioned features suggest that Konjiki-do, a well known national treasure, one of the buildings in Chuson-ji Temple of Iwate Prefecture, Japan, which was built of wood from the tree containing these five compounds, was kept from harm against noxious insects and wood-rotting fungi for a long time of about 840 years, until it was extensively repaired in 1962. In addition to Konjiki-do, there are some old famous Buddhist temples and Shinto shrines using Aomori Hiba. From the results, it was found that Aomori Hiba (Hinokiasunaro) is excellent for use as building materials.