RESUMEN

The aqueous extract of Persea americana leaves produced a dose-dependent inhibition of both phases of formalin pain test in mice, a reduction in mouse writhing induced by acetic acid and an elevation of pain threshold in the hot plate test in mice. The extract also produced a dose-dependent inhibition of carrageenan-induced rat paw oedema. The results obtained indicate that the extract possesses analgesic and anti-inflammatory effects.

Asunto(s)

Analgésicos no Narcóticos/farmacología , Analgésicos/farmacología , Lauraceae/química , Extractos Vegetales/farmacología , Hojas de la Planta/química , Animales , Femenino , Masculino , Ratones , Nigeria , Plantas Medicinales/química , Ratas , Ratas Wistar