RESUMEN
No disponible
Asunto(s)
Anciano , Femenino , Humanos , Resultado del Tratamiento , Omeprazol , Antiulcerosos , Buformina , Acidosis Láctica , Anafilaxia , Inyecciones Intravenosas , Hipoglucemiantes , Paro Cardíaco , Gastritis , Diabetes Mellitus Tipo 2Asunto(s)
Trastornos Relacionados con Cocaína/complicaciones , Enfermedades Pulmonares/etiología , Cocaína/toxicidad , Trastornos Relacionados con Cocaína/diagnóstico , Cocaína Crack/toxicidad , Humanos , Pulmón/efectos de los fármacos , Pulmón/fisiopatología , Enfermedades Pulmonares/diagnóstico , Terminología como AsuntoRESUMEN
OBJECTIVE: To study the evolution and ventilatory function measured by spirometry after surgery with the Harrington method for idiopathic thoracic scoliosis. PATIENTS AND METHODS: A prospective study with evaluation of changes in scoliosis angle following the Cobb method, as well as ventilatory parameters after surgery, measured after a mean time of 19.2 +/- 11.8 (range: 9-60) months post-surgery. Twenty patients were studied, 6 men and 14 women, with no previous respiratory conditions, with ages ranging from 12 and 35 years, and a mean of 16.3 +/- 4.6 years, and all of them with the diagnosis of idiopathic thoracic scoliosis and with pre-surgery angle of 59.9 degrees +/- 13.5 degrees. RESULTS: No statistically significant changes were observed in any of the ventilatory parameters considering both the absolute value and percentage of the theoretical value, although there was indeed a significant improvement in the scoliosis angle. CONCLUSIONS: In our study no ventilatory function improvement was observed after scoliosis surgery, although we cannot say that the results were the same if the previous thoracic deformity were more remarkable and caused greater changes in ventilatory parameters.
Asunto(s)
Pulmón/fisiopatología , Escoliosis/cirugía , Adolescente , Adulto , Niño , Femenino , Volumen Espiratorio Forzado , Humanos , Masculino , Estudios Prospectivos , Escoliosis/fisiopatología , Espirometría , Vértebras Torácicas , Capacidad VitalRESUMEN
We report three cases of women with abdominal pathology in which an elevated serum CA 125 tumor marker could have led to an erroneous diagnosis of ovarian carcinoma. However, after peritoneal biopsies were taken, tuberculosis was diagnosed. Furthermore, specific tuberculostatic treatment normalized serum CA 125 levels.
Asunto(s)
Biomarcadores de Tumor/sangre , Antígeno Ca-125/sangre , Neoplasias Ováricas/diagnóstico , Peritonitis Tuberculosa/diagnóstico , Adulto , Biopsia , Diagnóstico Diferencial , Femenino , Humanos , Peritoneo/patología , Peritonitis Tuberculosa/sangreRESUMEN
OBJECTIVE: The study of the disturbances of arterial gases and the changes in the arterial pH which are present in patients with liver cirrhosis and ascites and their modification after the disappearance of ascites by treatment. EXPERIMENTAL DESIGN: Open study,with protocol and prospective, to evaluate the changes in measurement of the arterial gases and acid-base, parameters in matching groups of patients. PATIENTS: We include 24 patients, 15 males and 9 females, without preliminary or cardio-respiratory pathology age range between 37 and 77 years, average of 56.8 years, all of them diagnosed of liver cirrhosis of different etiologies and with important ascites. All of them finished the study. RESULTS: In patients with liver cirrhosis and ascites a fall in the PaO2 and in the PaCO2 was demonstrated the pH in the upper limit of the normality compatible with hypoxemia and respiratory alkalosis. After the disappearance of the ascites, a significant improvement in the PaO2 (p < 0.05), without any changes in the PaCO2 and pH values was apparent. CONCLUSIONS: In patients with liver cirrhosis, with or without ascites, hyperventilation is present, that can be multifactorial in origin, but which really has an unknown cause. We have found no relationship with the circulating levels of progesterone.
Asunto(s)
Ascitis/fisiopatología , Cirrosis Hepática/fisiopatología , Intercambio Gaseoso Pulmonar , Equilibrio Ácido-Base , Adulto , Anciano , Ascitis/sangre , Ascitis/etiología , Dióxido de Carbono/sangre , Femenino , Humanos , Concentración de Iones de Hidrógeno , Cirrosis Hepática/sangre , Cirrosis Hepática/complicaciones , Masculino , Persona de Mediana Edad , Oxígeno/sangre , Estudios ProspectivosRESUMEN
In order to determine the validity for our population of the theoretical reference values available in the literature today, we studied respiratory muscle force by calculating maximum expiratory pressure PEmax and maximum inspiratory pressure (PImax) in 100 healthy subjects in Asturias (50 women) between 17 and 80 years-old (mean 40.4 +/- 19.3 years). We used the same methods and apparatus as Black and Hyatt and compared the results with theoretical values given by them as references corresponding to our subjects, according to age and sex. Values were significantly lower (p < 0.001) in our population for both parameters and for both men and women. In men PEmax was 69.7% and PImax was 88.5% of the theoretical values, in women PEmax was 60.9% and PImax was 82.9%. These figures indicate that the theoretical values given by Black and Hyatt are not valid for the population we studied and that normal reference values appropriate for each population, laboratory and apparatus must be obtained if valid conclusions are to be reached.
Asunto(s)
Mecánica Respiratoria/fisiología , Adolescente , Adulto , Anciano , Anciano de 80 o más Años , Femenino , Humanos , Masculino , Manometría/instrumentación , Manometría/métodos , Manometría/estadística & datos numéricos , Persona de Mediana Edad , Presión , Estudios Prospectivos , Valores de Referencia , Pruebas de Función Respiratoria/métodos , Pruebas de Función Respiratoria/estadística & datos numéricos , Estadísticas no ParamétricasRESUMEN
BACKGROUND: The thoracic cavity plays an important role in the mechanical ventilatory function, and the alteration of some of its structures, such as those which occur in decompensated cirrhosis of the liver, for example the presence of ascites and muscle atrophy, directly influence its normal function. METHODS: In the present study we have evaluated the ventilatory function and respiratory muscular tension by means of the calculation of volumes, flows and resistances of the airways, and also the maximum inspiratory and expiratory pressures (Pimax, Pemax). PATIENTS: One hundred patients with liver cirrhosis and ascites without associated respiratory illness, mean age 57 +/- 15 years (range 32-80), were studied. We evaluated the respiratory function before and after the disappearance of the ascites. RESULTS: A restrictive pattern was evident, and various parameters were altered. The most affected being that of the reserve expiratory volume. No associated bronchial obstruction was observed. Respiratory muscular tension was decreased in both the Pimax and the Pemax. With the disappearance of the ascites we found an improvement in the affected parameters, but this did not reach normality. CONCLUSION: In liver cirrhosis associated with ascites, the most common respiratory pattern, is a decrease in ventilatory function of a restrictive type, and also a decrease in the respiratory muscular tension. These alterations improve after the resolution of the ascites.
Asunto(s)
Ascitis/fisiopatología , Cirrosis Hepática/complicaciones , Cirrosis Hepática/fisiopatología , Respiración , Músculos Respiratorios/fisiología , Adulto , Anciano , Anciano de 80 o más Años , Ascitis/etiología , Femenino , Humanos , Masculino , Persona de Mediana Edad , Pruebas de Función Respiratoria , Músculos Respiratorios/fisiopatologíaRESUMEN
We present the most relevant data of a series of 8 cases of PTA coming from our environment. We highlight the onset of PTA with low doses of amiodarone (equal or lower than 400 mg/day), the affectation of only aged patients (range 63-77 years) and always, except in one case, during the first five years of treatment with amiodarone. Dyspnea was the most frequent symptom. The definition of PTA is mainly clinical-radiological and it has no biochemical, radiological or functional unique characteristics, determining the need for a careful differential diagnosis. The prognosis was excellent when the administration of amiodarone was stopped and, in some cases, steroids were added.