RESUMEN
BACKGROUND: The aim of the study was to determine the incidence of parasitic liver cysts. MATERIAL AND METHODS: In 1996-2000 at the Department of Infectious Diseases parasitic liver cysts were diagnosed in 31 patients. The diagnosis was based on imaging examinations (ultrasound, computerised tomography), serological reactions (ELISA, IHA) and histopathological investigation of the specimens obtained through fine-needle aspiration biopsy. RESULTS AND CONCLUSION: The latter followed the pre-treatment with antiparasitic drug and no significant complications were observed. On the basis of the criteria developed by our team (evident, highly probable and probable diagnosis), hydatid disease of the liver was diagnosed in 8 patients (25.8%). The remaining subjects, excluding one patient who underwent surgical treatment, received repeated treatment with imidazole derivatives (Zentel or Vermox).
Asunto(s)
Equinococosis Hepática/diagnóstico , Biopsia con Aguja , Preescolar , Diagnóstico Diferencial , Equinococosis Hepática/patología , Ensayo de Inmunoadsorción Enzimática , Femenino , Pruebas de Hemaglutinación , Humanos , Lactante , Masculino , Estudios ProspectivosRESUMEN
The aim of the study was to assess if Szczecin voivodeship is an area of endemic borreliosis, assess the risk due to B. burgdorferi infection in habitants and evaluate clinical manifestations of borreliosis. The study was conducted in 1993-1995, material comprised 299 persons (211 men and 88 women) aged from 3 to 78 years, divided into two groups. Group I consisted of foresters working in four forestry districts, occupationally exposed to tick bite. Group II was completed of Szczecin voivodeship habitants, sporadically exposed to tick bite. Control group consisted of 30 healthy persons without exposure to tick bite. Research programme of study comprised epidemiologic data, clinical examination, evaluation of serum anti-B.b antibodies in all persons and assessment of some infectious parameters (red cells sedimentation--RCS, leukocytosis and C-Reactive Protein--CRP) during borreliosis. High prevalence of borreliosis was noted in both groups. Risk of borreliosis was similar in four forestry districts (Tab. 1). The hazard of infection was not restricted to forest areas only but was present in some parts of Szczecin and its suburbs (parks and gardens). Infection by B.b. was observed in both males and females in all age groups. Risk of B.b infection increased accordingly to duration of exposure but in some examined persons after single tick bite the disease developed (Tab. 2). Some of infected persons do not demonstrate clinical symptoms of borreliosis (Tab. 3). In most cases the disease was diagnosed in early stage of infection (Tab. 4). During infection different organs and systems were involved (Tab. 5). In clinical study skin was the most often affected organ followed by nervous system and joints (Tab. 5, 7). Clinical manifestations comprised erythema migrans chronicum, radiculitis, arthritis, meningitis, encephalitis and uveitis (Tab. 6). Serological study revealed the presence of serum anti-B.b antibodies in 47.6% of examined persons with occupational risk involving tick bite, and 32.7% persons of sporadic risk with negative serology of borreliosis in control group (Tab. 8). The parameters of acute inflammatory phase (RCS, CRP, leukocytosis) are of limited value in diagnosis of borreliosis.
Asunto(s)
Mordeduras y Picaduras/epidemiología , Enfermedad de Lyme/epidemiología , Enfermedades Profesionales/epidemiología , Garrapatas , Adolescente , Adulto , Anciano , Animales , Grupo Borrelia Burgdorferi , Estudios de Casos y Controles , Niño , Preescolar , Comorbilidad , Femenino , Agricultura Forestal/estadística & datos numéricos , Humanos , Incidencia , Lactante , Enfermedad de Lyme/diagnóstico , Masculino , Persona de Mediana Edad , Polonia/epidemiología , Factores de RiesgoRESUMEN
The epidemiological situation of Szczecin following the liberation was both difficult and dangerous. Numerous cases of typhus, diphteria ague, venereal diseases, typhoid and dysentery were noted and an urgent need of dealing with them was necessary. Thus an infectious diseases ward was opened in 1945 at 4 Arkonska Str. Its organiser was dr Elzbieta Buk. Despite of lack of both medical staff and equipment as well as medicines in its first month of operation the ward had 160 patients. Mostly they suffered from typhus, diphtheria, dysentery and typhoid. Mortality was high: 37 patients died. Till the end of 1945 674 patients were treated, most in September. The patients were mostly Germans, Poles, Russians, Ukranians, Belorussians and occasionally French. The most frequent was typhus though there were cases of malaria and rabies. Typhoid TB, dysentery and diphtheria were also observed. In 1946/47 more wards were opened dealing with lung, skin, venereal and children's diseases. The last one directed by Dr Krystyna Stawiarska hod its scarlet fever and diphtheria sections and simultaneously an analytical and a bacteriological labs were set up and due to Dr Stanislae Swierczysski determination they enabled basic diagnostics. Slowly post-war epidemics were contained and both infections mortality and admissions grew smaller.
Asunto(s)
Enfermedades Transmisibles , Hospitales Especializados , Salud Pública , Guerra , Historia del Siglo XX , Humanos , Morbilidad , PoloniaRESUMEN
In the period of 1989-1995 seven patients with amebic liver abscess were observed in Clinic of Infectious Diseases of Pomeranian Medical School in Szczecin. The diagnosis has been made on the base of epidemiological data, presence of intrahepatic defect by a scanning procedure of liver (ultrasonography, CT, scintigraphy) and positive serologic test for amebiasis. All patients were male of Polish nationality, 29-57 years old, who became ill after travel to Africa or India. Intestinal amebiasis was present only in two cases. Five patients had acute onset of disease and two chronic. The most common complaints included fever, abdominal pain, anorexia. A cough, chest pain, diarrhea or weight lose were less common. At physical examination paleness of skin, subjaundice, abdominal tenderness, hepatomegaly and sometimes pleural effusion have been observed. Laboratory tests revealed high RBS, leucocytosis and mild anemia. Slightly higher serum level of bilirubin, alkaline phosphatase were transient. Trophozoits of Entamoeba histolytica have been found in stool specimens of one only patient. Amebic antibodies tested with indirect hemagglutination (IHA) were present in all cases. Visual technics have shown abscess of 3 to 9 cm in diameter located at right liver lobe. Six patients have been treated with both chemotherapy (metronidazole or/and dehydroemetine) and "skin needle" aspiration. In two cases recrudescence of abscess has been observed after one and three years respectively. These two patients have been undergone second course of treatment with using not only needle aspiration and metronidazole/dehydroemetine but luminal agents as well.
Asunto(s)
Absceso Hepático Amebiano/diagnóstico , Adulto , Animales , Diagnóstico por Imagen/métodos , Entamoeba histolytica/aislamiento & purificación , Heces/parasitología , Humanos , Incidencia , Absceso Hepático Amebiano/epidemiología , Absceso Hepático Amebiano/terapia , Masculino , Persona de Mediana Edad , Examen Físico , Polonia/epidemiología , Pruebas SerológicasRESUMEN
Thirty five patients with imported malaria were hospitalised in a period of 1980-93 in Department of Infectious Diseases of Pomeranian Medical School, Szczecin, Poland. The diagnosis of malaria was established on a base of clinical feature, the presence of Plasmodium in peripharal blood smears and, in some cases, on positive serological tests. Thirty two patients were Polish citizens, and three persons were foreigners. Malaria was caused mostly by invasion of Plasmodium falciparum (62.8), then P. vivax (31, 4), in 1 case--P. ovale and 1 case--mixed invasion occurred (P. falciparum and P. vivax). The majority of cases caused by P. falciparum were imported from Central Africa. Invasions of P. vivax were brought from North Africa, India and Middle East. Malaria in Polish patients was connected with occupational exposure and lack of proper antimalarial prophylaxis was obvious. A clinical course of disease was serious, with one mortal case. Fever, headache, abdominal pain, weakness, jaundice, insomnia were main complaints. Anemia, leucopenia, thrombocytopenia, hyperbilirubinemia, hypertransaminasemia and high serum concentration of urea were observed. A level of parasitemia in peripheral blood varied from minimal to very high (22.5%) in cases of P. falciparum invasions. In treatment chloroquine, fansidar, quinine, primaquine, halfan were used.
Asunto(s)
Malaria/epidemiología , Adulto , Femenino , Humanos , Incidencia , Tiempo de Internación , Malaria/diagnóstico , Malaria/tratamiento farmacológico , Masculino , Persona de Mediana Edad , Enfermedades Profesionales/epidemiología , Polonia/epidemiología , Pruebas SerológicasRESUMEN
Clinical course, early and late complications as well as treatment of ophthalmic zoster in 70 hospitalized patients are presented. Authors pay the attention to early treatment (general and topical) with Zovirax in prevention of ocular complications.
Asunto(s)
Herpes Zóster Oftálmico/tratamiento farmacológico , Aciclovir/uso terapéutico , Adulto , Anciano , Anciano de 80 o más Años , Femenino , Herpes Zóster Oftálmico/complicaciones , Humanos , Inosina Pranobex/uso terapéutico , Masculino , Persona de Mediana EdadRESUMEN
The clinical types of herpes zoster in 286 patients were observed. The differences in the course of disease in persons with and without decreased immunity are described. Some of the neurological complications depending on the localization of the herpes zoster are presented.