RESUMEN
Four comparable groups were constituted, of 14 bovines each. One was kept as a control group and the others were inoculated with Formidogel, Flury and modified Fuenzalida anti-rabies vaccines, respectively
After eight months, all the animals in the experiment were submitted to the "challenge", with the following results in mortality rates: control group, 12/13 (92.3 per cent); group inoculated with the Fuenzalida vaccine, 13/14 (92.9 per cent); group inoculated with the Flury vaccine, 6/13 (46.2 per cent); group inoculated with the Formidogel vaccine, 3/13 (23.1 per cent). According to this experiment, the Fuenzalida vaccine did not give satisfactory results with bovines; account must be taken of the modification introduced in its preparation
A statistical analysis of the results revealed that, at the 5 per cent rejection level adopted:
1) the mortality rate for the group inoculated with the Formidogel vaccine did not differ significantly from that of the group receiving the Flury vaccine;
2) the mortality rate for the group that received the Formidogel vaccine and for the group inoculated with the Flury vaccine was significantly lower than either that of the group inoculated with the modified Fuenzalida vaccine or that of the control group;
3) the mortality rate observed in the group inoculated with the modified Fuenzalida vaccine did not differ significantly from that of the group ...(AU)
Asunto(s)
Vacunas Antirrábicas/inmunología , Vacunas Antirrábicas/terapia , Rabia/inmunología , Enfermedades de los Bovinos , BrasilRESUMEN
The authors worked with a total of 770 bats. Of these, 556 were vampire bats and included 496 Desmodus rotundus rotundus (Geoffroy), 52 Diphylla ecaudata (Spix) and 8 Diaemus youngi (Jentink). Most of the bats came from areas in which rabies was prevalent. Of these areas the valley of the River Paraiba was of special importance, for these foci of rabies had existed since 1960. In this region 292 Desmodus were captured and from them 11 specimens of rabies virus were isolated, in all cases from brain tissue. The isolations were confirmed by the presence of Negri bodies in the brains of inoculated mice and by the serum-neutralization test. Two were obtained from bats found in stables during the day-time, one of which was received in an advanced state of putrefaction. These authors also discuss certain aspects of rabies outbreaks related to the isolations of virus, in particular an outbreak of rabies in cattle in Maraba Paulista, where the bats discovered were not vampire bats but frugivorous or insectivorous bats
Asunto(s)
Virus de la Rabia/aislamiento & purificación , Quirópteros/inmunología , BrasilRESUMEN
The authors worked with a total of 770 bats. Of these, 556 were vampire bats and included 496 Desmodus rotundus rotundus (Geoffroy), 52 Diphylla ecaudata (Spix) and 8 Diaemus youngi (Jentink). Most of the bats came from areas in which rabies was prevalent. Of these areas the valley of the River Paraiba was of special importance, for these foci of rabies had existed since 1960. In this region 292 Desmodus were captured and from them 11 specimens of rabies virus were isolated, in all cases from brain tissue. The isolations were confirmed by the presence of Negri bodies in the brains of inoculated mice and by the serum-neutralization test. Two were obtained from bats found in stables during the day-time, one of which was received in an advanced state of putrefaction. These authors also discuss certain aspects of rabies outbreaks related to the isolations of virus, in particular an outbreak of rabies in cattle in Maraba Paulista, where the bats discovered were not vampire bats but frugivorous or insectivorous bats
Asunto(s)
Virus de la Rabia , Quirópteros , BrasilRESUMEN
Four comparable groups were constituted, of 14 bovines each. One was kept as a control group and the others were inoculated with Formidogel, Flury and modified Fuenzalida anti-rabies vaccines, respectively
After eight months, all the animals in the experiment were submitted to the "challenge", with the following results in mortality rates: control group, 12/13 (92.3 per cent); group inoculated with the Fuenzalida vaccine, 13/14 (92.9 per cent); group inoculated with the Flury vaccine, 6/13 (46.2 per cent); group inoculated with the Formidogel vaccine, 3/13 (23.1 per cent). According to this experiment, the Fuenzalida vaccine did not give satisfactory results with bovines; account must be taken of the modification introduced in its preparation
A statistical analysis of the results revealed that, at the 5 per cent rejection level adopted:
1) the mortality rate for the group inoculated with the Formidogel vaccine did not differ significantly from that of the group receiving the Flury vaccine;
2) the mortality rate for the group that received the Formidogel vaccine and for the group inoculated with the Flury vaccine was significantly lower than either that of the group inoculated with the modified Fuenzalida vaccine or that of the control group;
3) the mortality rate observed in the group inoculated with the modified Fuenzalida vaccine did not differ significantly from that of the group ...(AU)