RESUMEN

We present a 3-year-old girl who had chronic recurrent multifocal osteomyelitis caused by Coxiella burnetii despite long-term dual antibiotic therapy. Excellent clinical response was achieved and sustained when immunomodulatory therapy with interferon-γ was initiated. This is the case of a first child who was successfully treated with interferon-γ as adjuvant therapy for chronic multifocal Q fever osteomyelitis.

Asunto(s)

Factores Inmunológicos/uso terapéutico , Interferón gamma/uso terapéutico , Osteomielitis/tratamiento farmacológico , Fiebre Q/tratamiento farmacológico , Antibacterianos/uso terapéutico , Quimioterapia Adyuvante , Preescolar , Coxiella burnetii , Femenino , Humanos , Osteomielitis/diagnóstico , Osteomielitis/etiología , Fiebre Q/complicaciones , Fiebre Q/diagnóstico , Resultado del Tratamiento