Asunto(s)
Eugenol/efectos adversos , Eugenol/normas , Preparaciones de Plantas/efectos adversos , Preparaciones de Plantas/normas , Dermatitis Alérgica por Contacto/etiología , Eugenol/aislamiento & purificación , Eugenol/envenenamiento , Humanos , Preparaciones Farmacéuticas Odontológicas/efectos adversos , Preparaciones Farmacéuticas Odontológicas/química , Preparaciones Farmacéuticas Odontológicas/normas , Preparaciones de Plantas/química , Preparaciones de Plantas/envenenamiento , Intoxicación/diagnóstico , Intoxicación/etiología , Intoxicación/terapiaAsunto(s)
Trastornos Cerebrovasculares/complicaciones , Trastornos del Conocimiento/etiología , Fármacos Neuroprotectores/uso terapéutico , Piracetam/uso terapéutico , Anciano , Atención Ambulatoria , Enfermedad Crónica , Progresión de la Enfermedad , Femenino , Humanos , Masculino , Persona de Mediana Edad , Pruebas Neuropsicológicas , Índice de Severidad de la EnfermedadAsunto(s)
Trastornos Cerebrovasculares/complicaciones , Trastornos del Conocimiento/etiología , Fármacos Neuroprotectores/uso terapéutico , Piracetam/uso terapéutico , Anciano , Atención Ambulatoria , Enfermedad Crónica , Trastornos del Conocimiento/diagnóstico , Progresión de la Enfermedad , Femenino , Humanos , Masculino , Persona de Mediana Edad , Pruebas Neuropsicológicas , Índice de Severidad de la EnfermedadRESUMEN
The aim of this paper was to provide a theoretical and experimental rationale for the extension of the raw material base for the production of phytopreparations from cultivated plants and food-industry waste, the development and standardization of scientifically grounded methods for their utilization and manufacture of pharmaceuticals. In the last years, the phytochemical composition of more than 20 species of officinal plants extensively cultivated in this country has been studied in the Department of General Chemistry, I.M.Sechenov Moscow Medical Academy. Oil content, composition of fatty acids, and tocopherol levels were determined in various plant tissues. The data obtained were used to improve normative documentation on raw materials, pharmaceutical substances, and medicinal agents. General technical approaches to the standardization of phy-topreparations were realized in the research carried out by the Department to develop methods for quality control of stomatological materials and therapeutic agents.
Asunto(s)
Materiales Dentales/química , Industria Farmacéutica/normas , Estructuras de las Plantas , Materiales Dentales/normas , Humanos , Control de CalidadRESUMEN
Ginos, a derivative of extract Ginkgo Biloba, was administered to 100 patients, aged from 45 to 80 years, mean age 62,3+/-0,7), in dosage 120 mg 3 times daily during 3 months in addition to somatic therapy. A patient's state was assessed before, during and after the treatment using clinical methods and a battery of psychometric scales and neuropsychological tests. A significant improvement of neurological and mental status was found in 90 (90%) of patients that was most distinctly observed in the dynamics of their global state and neurocognitive performance on the MMSE and other tests. The effect of the drug was less pronounced for affective disorders - depression and anxiety. The drug was well-tolerated by patients.
Asunto(s)
Trastornos Cerebrovasculares/tratamiento farmacológico , Ginkgo biloba , Pacientes Ambulatorios , Preparaciones de Plantas/uso terapéutico , Anciano , Anciano de 80 o más Años , Trastornos Cerebrovasculares/diagnóstico , Trastornos Cerebrovasculares/psicología , Enfermedad Crónica , Cognición/efectos de los fármacos , Progresión de la Enfermedad , Relación Dosis-Respuesta a Droga , Esquema de Medicación , Femenino , Estudios de Seguimiento , Humanos , Imagen por Resonancia Magnética , Masculino , Escala del Estado Mental , Persona de Mediana Edad , Fitoterapia , Psicometría/métodos , Tomografía Computarizada por Rayos X , Resultado del TratamientoRESUMEN
The waste of some fruits, berries, and vegetables, which are accumulated by food industries (juice-extracting, wine, confectionery, and other industries) and generally completely utilized was pharmacognistically and phytochemically analyzed. The phytochemical analysis showed that the study objects (black currant, raspberry, viburnum, red and black mountain ashes, and grape fruit bagasses and melon, squash, and tomato seeds) contain a lot of lipophilic fractions (fatty oil) that present a complex of valuable biologically active substances. The developed recipes of phytopreparations are safe-and-easy-to-use and can be successfully used in patients with chronic inflammatory uterine appendage diseases and in those who present a difficult cohort of patients with lower urinary tract dysfunctions which are hardly correctable and require sophisticated choice of adequate drug therapy.