RESUMEN
OBJECTIVE: To determine the correlation between two methods of measurement of total PSA (PSA-T) and free PSA (PSA-F) and the utility of the PSA-F/PSA-T ratio in patients with PSA-T between 4 and 10 ng/ml suspected as having prostate cancer. METHODS: Determinations of both PSA-T and PSA-F were performed using two different techniques in 91 patients suspected as having prostate cancer. Diagnosis was made on the findings of biopsy and the complementary tests. RESULTS: The following correlation was found for the two techniques: R = 0.99 and p < 0.05 for PSA-T, and R = 0.85 and p < 0.05 for PSA-F. For PSA-T values of 4-10 ng/ml and PSA-F greater than 25%, we found two patients with prostate cancer. For a PSA-F/PSA-T ratio less than 9%, all cases had prostate cancer. Three cases with bone metastasis had PSA-T values less than 10 ng/ml. CONCLUSIONS: A PSA-F/PSA-T ratio greater than 25% does not exclude malignancy in patients with a total PSA of 4-10 ng/ml; values less than 9% correspond to prostate cancer. Bone metastasis was found with both methods in patients with total PSA values less than 10 ng/ml.
Asunto(s)
Carcinoma/diagnóstico , Antígeno Prostático Específico/análisis , Hiperplasia Prostática/diagnóstico , Neoplasias de la Próstata/diagnóstico , Biopsia , Diagnóstico Diferencial , Humanos , Masculino , Juego de Reactivos para DiagnósticoAsunto(s)
Hígado Graso Alcohólico/diagnóstico por imagen , Hepatitis Alcohólica/diagnóstico por imagen , Cirrosis Hepática Alcohólica/diagnóstico por imagen , Adulto , Anciano , Várices Esofágicas y Gástricas/diagnóstico por imagen , Femenino , Hernia Hiatal/diagnóstico por imagen , Humanos , Hígado/diagnóstico por imagen , Masculino , Persona de Mediana Edad , Radiografía , CintigrafíaRESUMEN
Twenty cases of refractory anemia were studied by means of ferrokinetic analysis with Fe-59. An accelerated plasma clearing, a diminished iron uptake by red cells, and a decreased bone marrow activity were found. Half of the cases showed secondary liver and spleen hemochromatosis. The incidence of malignant tumors observed in the studied refractory anemias was 35% (7 out of 20 cases, corresponding to 4 solid tumors and 3 leukemias). The authors suggest the convenience to study erythropoiesis in anemias with an obscure origin using the ferrokinetic procedure with Fe-59.
Asunto(s)
Anemia Refractaria/complicaciones , Hierro/metabolismo , Leucemia/etiología , Neoplasias/etiología , Adulto , Anciano , Anemia Refractaria/metabolismo , Médula Ósea/metabolismo , Eritropoyesis , Femenino , Hemocromatosis/etiología , Humanos , Cinética , Masculino , Persona de Mediana EdadRESUMEN
A group of 122 breast cancer patients, 42 of them with bone metastases are studied, and the role of the radioisotopic whole body scanning and the serial skeletal radiography are considered.
Asunto(s)
Neoplasias Óseas/secundario , Neoplasias de la Mama , Carcinoma Intraductal no Infiltrante/secundario , Adulto , Anciano , Neoplasias Óseas/diagnóstico por imagen , Carcinoma Intraductal no Infiltrante/diagnóstico por imagen , Reacciones Falso Negativas , Reacciones Falso Positivas , Femenino , Humanos , Persona de Mediana Edad , Radiografía , Cintigrafía , Recuento Corporal TotalAsunto(s)
Brucelosis/diagnóstico por imagen , Adolescente , Adulto , Anciano , Niño , Femenino , Humanos , Hígado/diagnóstico por imagen , Masculino , Persona de Mediana Edad , CintigrafíaRESUMEN
The administration of radioactive phosphorus (P-32) for the treatment of pain in metastatic bone lesions from breast cancer shows palliative effects lasting three to nine months. The evolution of the disease is not modified.