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Nuclear matrix protein (NXP-2) positive amyopathic dermatomyositis (DM) may present without classic symptoms like muscle weakness, dysphagia, and edema, and mimic conditions like cutaneous lupus. Given DM's association with malignancy and interstitial lung disease, prompt and accurate diagnosis is important. Testing for myositis-specific antibodies aids diagnosis in ambiguous cases.

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Existing water and wastewater treatment techniques are becoming increasingly difficult to employ due to the discovery of new toxins, the rapid development of population and industrial activities, and the limited quantity of water resources. Treatment of wastewater is a critical need in modern civilization due to a scarcity of water resources and rising industrial activity. Some of the techniques utilized include adsorption, flocculation, filtration, and others, although they are only used for primary wastewater treatment. However, the development and deployment of modern wastewater management with high efficiency and low capitalization are critical in terms of mitigating the environmental consequences of waste. The employment of different nanomaterials in the treatment of wastewater has opened up a world of possibilities for heavy metal and pesticide removal, as well as the treatment of microbes and organic contaminants in wastewater. Nanotechnology is a rapidly evolving technology because of certain nanoparticle's outstanding physiochemical and biological capabilities as contrasted to bulk counterparts. Secondly, it has been established that this is a cost-effective treatment strategy with significant potential in wastewater management, transcending the limitations imposed by currently existing technology. Advances in nanotechnology to reduce water contamination have been presented in this review, including the use of various nanomaterials such as nanocatalysts, nanoadsorbents, and nanomembranes in the treatment of wastewater containing organic contaminants, hazardous metals, and virulent pathogens.

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A 54-year-old African American male with systemic lupus erythematosus and chronic alcoholic hepatitis presented with recurrent fever, pancytopenia, transaminitis, weight loss, and widespread violaceous tender plaques. Skin biopsy revealed hemophagocytic histiocytes leading to a diagnosis of cytophagic histiocytic panniculitis in the setting of lupus panniculitis. During workup, an axillary lymph node biopsy mimicked Kikuchi-Fujimoto's disease. Treatment with tapering high-dose glucocorticoids, mycophenolate mofetil, and hydroxychloroquine induced remission of the disease. We believe the comorbid conditions of Kikuchi-Fujimoto-like pathology and cytophagic histiocytic panniculitis have not been documented in the literature to date in a patient with systemic lupus erythematosus.

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The human coronavirus disease-2019 (COVID-19) caused by SARS-CoV-2 is now a global pandemic. Personal hygiene such as hand-washing, the use of personal protective equipment, and social distancing via local and national lockdowns are used to reduce the risk of transmission of SARS-CoV-2. COVID-19 and the associated lockdowns may have significant impacts on environmental quality and ergonomics. However, limited studies exists on the impacts of COVID-19 and the associated lockdowns on environmental quality and ergonomics in low-income settings. Therefore, the present study investigated the impacts of the COVID-19 outbreak on socioeconomics, ergonomics and environment (water quality, air quality and noise) in Uttarakhand, India. Approximately 55% of respondents experienced headaches, and the other common health-related issue was back pain, with 45% of respondents having problems with their backs. Water and air quality significantly improved during the lockdown relative to the pre-lockdown period, but was observed to return to their previous characteristics afterwards. Lockdowns significant increased the concentration of indoor air pollutants while noise pollution levels significantly declined. In summary, lockdowns have adverse impacts on ergonomics, resulting in work-related human health risks. The impacts of lockdowns on environmental quality are mixed: temporary improvements on water and air quality, and noise reduction were observed, but indoor air quality deteriorated. Therefore, during lockdowns there is a need to minimize the adverse environmental and ergonomic impacts of lockdowns while simultaneously enhancing the beneficial impacts.

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Population form a homeostat with environment where they live and exchange continuous gas for their respiration, which is the primary pathway for the pollutants to enter into human metabolism. The pollution present indoor is due to multiple sources like electronic and electrical equipment, clothes, furniture and other anthropogenic activity. The concentration of these pollutants changes with time and depends mainly on source type (continuous/intermittent), time of the operation and release/ventilation/wind velocity/pollutant dispersion and anthropogenic activity. It has been observed that equipment like printers, printing machines, photocopiers, etc., releases several pollutants like volatile organic compounds (VOCs), ozone (O3), semi-volatile organic compounds, benzene (C6H6), toluene and suspended particulate matter during operation. This work represents the emissions of VOCs, benzene, and toluene during photocopy. The numerical validation of results was done using Fluent, which is an application-based software which helps in physical modeling describing air flow and effect of multiple parameter on it like temperature and no of printing/photocopy (in proposed experiment) with respect to time. It has been observed from the results that the emissions of VOCs, benzene, and toluene increase from 0.09 to 1.13 PPM, 0.17 to 1.87 PPM and 30 to 235 PPM, respectively, as the operating duration, temperature (35-40 °C) and rate of printing/photocopying increase (120-200/h), and it is because printer/photocopy machine uses heat and pressure to fix an image on the paper surface which subsequently result in higher emission. Multiple adverse health, safety and environmental impacts due to operation of photocopy/printing call for in-depth study, guidance, and monitoring of the workers occupationally associated with this operation for their well-being.

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"Knowledge is power" and distribution of knowledge is fueled by printing and photocopying industry. Even as printing and photocopying industry have revolutionized the availability of documents and perceptible image quickly at extremely inexpensive and affordable cost, the boon of its revolution has turned into a bane by irresponsible, uncontrolled and extensive use, causing irreversible degradation to not only ecosystem by continuous release of ozone and other volatile organic compounds (VOCs) but also the health of workers occupationally exposed to it. Indoor ozone level due to emission from different photocopying equipment's increases drastically and the condition of other air quality parameters are not different. This situation is particularly sedate in extremely sensitive educational and research industry where sharing of knowledge is extremely important to meet the demands. This work is an attempt to catalogue all the environmental as well as health impacts of printing or photocopying. It has been observed that printing/photocopying operation is a significant factor contributing to indoor air quality degradation, which includes increase in concentration of ozone, VOCs, semi-volatile organic compounds (SVOCs) and heavy metals such as cadmium, selenium, arsenic, zinc, nickel, and other pollutants from photocopy machines. The outcome of this study will empower the manufactures with information regarding ozone and other significant emission, so that their impact can be reduced.

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