RESUMEN

We determined the intra- and postoperative plasma concentrations of cytokines (tumor necrosis factor [TNF]-Alpha, interleukin [IL]-1Beta, IL-6, and IL-8) in oral surgery patients with procedures ranging in duration from 20 to 375 min and investigated their relationship to the intensity of the surgical stress over time. No significant differences from baseline levels were observed in the levels of TNF-Alpha, IL-1Beta, and IL-8. By contrast, increased IL-6 levels were noted only on the first postoperative day, when they reached 1500% of the baseline level, after which they decreased to preoperative levels by the third postoperative day and tended to reflect the intensity of surgical stress.

Asunto(s)

Interleucinas/sangre , Procedimientos Quirúrgicos Orales , Factor de Necrosis Tumoral alfa/análisis , Adulto , Análisis de Varianza , Pérdida de Sangre Quirúrgica , Femenino , Estudios de Seguimiento , Humanos , Interleucina-1/sangre , Interleucina-6/sangre , Interleucina-8/sangre , Periodo Intraoperatorio , Masculino , Persona de Mediana Edad , Periodo Posoperatorio , Estrés Fisiológico/sangre , Factores de Tiempo