RESUMEN
Biopsies taken from various regions of the duodenal mucosa were investigated with a quantitative histological method with a view to frequency, quantity, and localisation of the duodenitis in clinically proven chronic pancreatitis. The histologic classification of duodenitis was made according to Whitehead et al. Out of 46 patients suffering from a chronic pancreatitis, 19 had a duodenitis grade 1 in the pars superior and pars descendens. A more frequent occurrence of duodenitis with concomitant chronic gastritis or a pathologic condition of the bile duct or a chronic alcohol abuse could not be proved statistically.
Asunto(s)
Duodenitis/complicaciones , Pancreatitis/complicaciones , Anciano , Biopsia , Enfermedad Crónica , Duodenitis/patología , Duodeno/patología , Femenino , Humanos , Mucosa Intestinal/patología , Masculino , Persona de Mediana Edad , Pancreatitis/patologíaRESUMEN
The activities of enteropeptidase, alanine aminopeptidase, sucrase, and leucine aminopeptidase were determined in mucosa biopsies taken from three defined places of the duodenum and in duodenal juice. We examined 23 adults with a histological proven normal mucosa and 10 patients suffering from duodenitis grade I. Using multivariate evaluation of all the four enzyme activities of the three mucosa sites, we could differentiate duodenitis from normal mucosa with an efficiency of 88%.
Asunto(s)
Duodenitis/diagnóstico , Enzimas/metabolismo , Mucosa Intestinal/enzimología , Adulto , Anciano , Aminopeptidasas/metabolismo , Biopsia , Antígenos CD13 , Duodenitis/enzimología , Duodenitis/patología , Duodeno/enzimología , Duodeno/patología , Enteropeptidasa/metabolismo , Femenino , Glicósido Hidrolasas/metabolismo , Humanos , Mucosa Intestinal/patología , Secreciones Intestinales/enzimología , Leucil Aminopeptidasa/metabolismo , Masculino , Persona de Mediana Edad , beta-FructofuranosidasaRESUMEN
In an autoptic study the coincidence of carcinomas of the gastrointestinal tract and nodular lymphoid hyperplasia (NLH) of the duodenum was studied histologically. Out of sixty cases of carcinomas in the gastrointestinal tract not one case of concomitant NLH in the duodenum could be demonstrated, nor in the first section of the jejunum, which was examined for comparison's sake. A connection between NLH and carcinomas of the gastrointestinal tract, as pointed out in the literature, could not be confirmed through this study.
Asunto(s)
Enfermedades Duodenales/patología , Neoplasias Gastrointestinales/patología , Mucosa Intestinal/patología , Tejido Linfoide/patología , Adulto , Anciano , Duodeno/patología , Femenino , Humanos , Hiperplasia , Yeyuno/patología , Ganglios Linfáticos/patología , Masculino , Persona de Mediana EdadRESUMEN
95 cases with primary malignant thyroid tumours underwent surgery from 1965 to 1977. In view of the interdisciplinary character of treatment and independent of histological differentiation, total thyroidectomy should be performed. Differentiated carcinomas should be treated by selective dissection of suspected cervical lymph nodes. Surgical intervention of undifferentiated and medullary carcinomas should be followed by unilateral or bilateral neck-dissection. The survival rate is shown to depend on histological stage and extension of the tumour.
Asunto(s)
Neoplasias de la Tiroides/cirugía , Adenocarcinoma/cirugía , Adenoma/cirugía , Adulto , Anciano , Carcinoma/cirugía , Carcinoma Papilar/cirugía , Carcinoma de Células Escamosas/cirugía , Femenino , Bocio Nodular/cirugía , Enfermedad de Hodgkin/cirugía , Humanos , Escisión del Ganglio Linfático , Masculino , Persona de Mediana Edad , Estadificación de Neoplasias , Neurilemoma/cirugía , Quistes no Odontogénicos/cirugía , Complicaciones Posoperatorias/mortalidad , Pronóstico , Neoplasias de la Tiroides/patología , TiroidectomíaRESUMEN
On the basis of two own observations the clinical and radiological routine methods undergo a critical judgment concerning their valency for the diagnosis of Wegener's granulomatosis. The two patients showed the picture of a severe septical disease with high fever and expressed inflammatory changes of the biological reactions. In the first observation a pulmonary round focus and terminally the renal failure, in the second case severe inflammatory changes of the lungs without response to antibiotic therapy were in the foreground. The appearance of this disease as generalized vasculitis is conditioned by the manifold clinical symptomatology and thus renders the diagnostics extraordinarily difficult. The simultaneous affection of the nasopharyngeal space, of the lung and the kidneys may be a guide for the diagnosis. The X-ray findings of the lung are not able to found sufficiently the diagnosis.
Asunto(s)
Granulomatosis con Poliangitis/diagnóstico , Adulto , Glomerulonefritis/patología , Granulomatosis con Poliangitis/diagnóstico por imagen , Granulomatosis con Poliangitis/patología , Humanos , Pulmón/patología , Masculino , Persona de Mediana Edad , Neumonía/patología , Tomografía por Rayos X , Traqueítis/patologíaRESUMEN
It is reported on 37 patients in whom on the basis of the clinical suspicion of a glomerulonephritis a biopsy of the kidneys was carried out, and after treatment in these patients a rebiopsy was carried out 21 months later in order to examine clinical and histological changes during this period. Hereby could be established that the rebiopsy only six times evoked an apparant improvement, whereas the other cases showed clinical findings or deterioration and only in half the cases a correspondence between clinical and histological developmental tendencies was recognizable. As conclusion indications to rebiopsy are proposed.