RESUMEN
The burgeoning field of nanotechnology has ushered in innovative Novel drug delivery systems (NDDS) that enhance the efficacy, safety, and patient compliance of pharmaceutical treatments. This study explores the synthesis and application of silver nanoparticles (AgNPs) using green chemistry approaches, specifically leveraging plant extracts as reducing agents. AgNPs, known for their unique physical and chemical properties, including antimicrobial capabilities, offer significant potential in modern drug delivery. This study investigates the potential of using Allium cepa peel waste for the green synthesis of silver nanoparticles. This study also revealed the resultant formation of silver nanoparticles through microscopy and UV spectroscopy, which were further analyzed by Scanning Electron Microscopy. This green synthesis method not only aligns with environmentally friendly practices but also provides a cost-effective and scalable approach to nanoparticle production. We formulated a hair dye incorporating these AgNPs and evaluated its physicochemical parameters, demonstrating enhanced performance compared to control formulations without nanoparticles. This work underscores the promise of green-synthesized nanoparticles in developing advanced drug delivery systems, offering insights into future applications in anticancer and antimicrobial treatments. Our findings advocate for the broader adoption of sustainable nanotechnology in pharmaceutical sciences, potentially revolutionizing the treatment landscape with safer and more effective therapeutic options.
Asunto(s)
Nanopartículas del Metal , Cebollas , Extractos Vegetales , Plata , Cebollas/química , Plata/química , Nanopartículas del Metal/química , Extractos Vegetales/química , Tinturas para el Cabello/química , Tecnología Química Verde , Sistemas de Liberación de MedicamentosRESUMEN
Ameloblastoma is a benign odontogenic neoplasm which frequently affects the mandible. The term ameloblastoma includes several clinicoradiological and histological types. Apart from the most commonly encountered clinicopathologic models, there are few variants, whose biological profile is unknown or not elicited. Among these types, unicystic ameloblastoma is the least encountered variant of the ameloblastoma. Unicystic ameloblastoma refers to those cystic lesions that show clinical, radiographic, or gross features of a jaw cyst but on histologic examination show a typical ameloblastomatous epithelium lining the cyst cavity, with or without luminal and/or mural tumor proliferation. Unicystic ameloblastoma is a less encountered variant of the ameloblastoma and is believed to be less aggressive. As this tumor shows considerable similarities with dentigerous cysts, both clinically and radiographically, the biologic behaviour of this tumor group was reviewed. Moreover, recurrence of unicystic ameloblastoma may be long delayed, and a long-term postoperative followup is essential for proper management of these patients. Here we are presenting a case of unicystic ameloblastoma in an 18-year-old female patient.