RESUMEN

The presence of antibiotics in water sources is a significant concern due to their potential environmental impact and the risks to human health. In the present research, hierarchically mesoporous UiO-66 (HP-UiO-66) with a high surface area (1011 m2/g) and large pore volume was synthesized using the reflux method on the liter scale. The successful synthesis was confirmed by FT-IR, XRD, FESEM/EDS, N2-adsorption/desorption, and zeta potential techniques. The HP-UiO-66 was utilized to remove two large structure antibiotics, chlortetracycline hydrochloride (CTC), and oxytetracycline (OTC). Box Behnken design was used to investigate the factors affecting the removal process and the interactions between them. The maximum adsorption capacities for OTC and CTC antibiotics were 252.9 mg/g and 234.2 mg/g at 35 °C, respectively. The sum of the normalized error method was applied to the analysis of various error functions in the nonlinear fitting of equilibrium and kinetic data. The CTC and OTC adsorption kinetic followed a fractal-like pseudo-second-order model. The Langmuir isotherm fitted well to adsorption data. The results demonstrate that HP-UiO-66 can be used as a recyclable and efficient adsorbent for large molecule antibiotics removal.

Asunto(s)

Antibacterianos , Aguas Residuales , Contaminantes Químicos del Agua , Antibacterianos/química , Contaminantes Químicos del Agua/química , Aguas Residuales/química , Adsorción , Cinética , Purificación del Agua/métodos , Oxitetraciclina/química , Clortetraciclina/química , Espectroscopía Infrarroja por Transformada de Fourier , Porosidad

RESUMEN

Among the catecholamines, dopamine (DA) is essential in regulating multiple aspects of the central nervous system. The level of dopamine in the brain correlates with neurological diseases such as Parkinson's disease (PD). However, dopamine is unable to cross the blood-brain barrier (BBB). Therefore, levodopa (LD) is used to restore normal dopamine levels in the brain by crossing the BBB. Thus, the control of LD and DA levels is critical for PD diagnosis. For this purpose, LiSr0.0985VO4:0.015Eu3+ (LSV:0.015Eu3+) nanoplates were synthesized by the microwave-assisted co-precipitation method, and have been employed as an optical sensor for the sensitive and selective detection of catecholamines. The synthesized LSV:0.015Eu3+ nanoplates emitted red fluorescence with a high quantum yield (QY) of 48%. By increasing the LD and DA concentrations, the fluorescence intensity of LSV:0.015Eu3+ nanoplates gradually decreased. Under optimal conditions, the linear dynamic ranges were 1-40 µM (R2 = 0.9972) and 2-50 µM (R2 = 0.9976), and the detection limits (LOD) were 279 nM, and 390 nM for LD and DA, respectively. Herein, an instrument-free, rapid quantification visual assay was developed using a paper-based analytical device (PAD) with LSV:0.015Eu3+ fixed on the bacterial cellulose nanopaper (LEBN) to determine LD and DA concentrations with ease of operation and low cost. A smartphone was coupled with the PAD device to quantitatively analyze the fluorescence intensity changes of LSV:0.015Eu3+ using the color recognizer application (APP). In addition, the LSV:0.015Eu3+ nanosensor showed acceptable repeatability and was used to analyze real human urine, blood serum, and tap water samples with a recovery of 96-107%.

RESUMEN

Chromium (Cr), as a highly toxic heavy metal ion, is still a severe environmental issue, although many research efforts have been put into its removal from water. Polyaniline (PANI), as a conductive polymer, demonstrated great capability in heavy metal adsorption due to its low cost, ease of synthesis, reversible redox behavior, and chemical stability. However, using PANI powder alone in heavy metal removal causes secondary pollution and aggregation in water. The PANI coating on a substrate could tackle this problem. In this study, polyaniline-coated polyamide6 (PA6/PANI) nano-web membrane was used for the removal of Cr(VI) in both adsorption and filtration-adsorption modes. The PA6/PANI nano-web membrane was fabricated via PA6 electrospinning followed by in-situ polymerization of the aniline monomer. The electrospinning condition of PA6 was optimized by the Taguchi method. The PA6/PANI nano-web membrane was characterized by FESEM, N2-adsorption/desorption, FT-IR, contact angle measurement, and tensile test. FT-IR and FESEM results demonstrated the successful synthesis of PA6/PANI nano-web and PANI homogeneous coating on PA6 nanofibers, respectively. The N2 adsorption/desorption results indicated that the pore volume of the PA6/PANI nano-web decreased by 39% compared to PA6 nanofibers. The tensile test and water contact angle studies showed that the coating of PANI on PA6 nanofibers improves the mechanical properties and hydrophilicity of PA6 by 10% and 25%, respectively. The application of PA6/PANI nano-web in the removal of Cr(VI) in batch and filtration modes exhibits excellent removal of 98.4 and 86.7%, respectively. A pseudo first order model well described the adsorption kinetics, and the adsorption isotherm was best fitted by the Langmuir model. A black box modeling approach based on artificial neural networks (ANN) was developed to predict the removal efficiency of the membrane. The superior performance of PA6/PANI in both adsorption and filtration-adsorption systems makes it a potential candidate for the removal of heavy metals from water on an industrial scale.

Asunto(s)

Metales Pesados , Contaminantes Químicos del Agua , Adsorción , Espectroscopía Infrarroja por Transformada de Fourier , Contaminantes Químicos del Agua/análisis , Cromo/química , Compuestos de Anilina/química , Cinética

RESUMEN

Sulfur- and nitrogen-doped carbon quantum dots (S,N-CQDs) were synthesized using feijoa leaves as a green precursor via a novel route. Spectroscopic and microscopic methods such as X-ray photoelectron spectroscopy, fluorescence spectroscopy, and high-resolution transmission electron microscopy were used to analyze the synthesized materials. The blue emissive S,N-CQDs were applied for qualitative and quantitative determination of levodopa (L-DOPA) in aqueous environmental and real samples. Human blood serum and urine were used as real samples with good recovery of 98.4-104.6 and 97.3-104.3%, respectively. A smartphone-based fluorimeter device was employed as a novel and user-friendly self-product device for pictorial determination of L-DOPA. Bacterial cellulose nanopaper (BC) was used as a substrate for S,N-CQDs to make an optical nanopaper-based sensor for L-DOPA determination. The S,N-CQDs demonstrated good selectivity and sensitivity. The interaction of L-DOPA with the functional groups of the S,N-CQDs via the photo-induced electron transfer (PET) mechanism quenched the fluorescence of S,N-CQDs. The PET process was studied using fluorescence lifetime decay, which confirmed the dynamic quenching of S,N-CQD fluorescence. The limit of detection (LOD) of S,N-CQDs in aqueous solution and the nanopaper-based sensor was 0.45 µM in the concentration range of 1-50 µM and 31.05 µM in the concentration range of 1-250 µM, respectively.

RESUMEN

In this work, a new highly water-soluble copolymer of polyacrylic acid with polyaniline is introduced. Acrylic acid was polymerized via the Reversible Addition Fragmentation Chain Transfer method (RAFT) in the presence of an initiator and the obtained polyacrylic acid was copolymerized with aniline at room temperature. As the main achievements of this work, the resulting block copolymer with nanosized structure revealed favorable solubility in polar solvents, as well as excellent antibacterial and anticancer activities. Therefore, it is an appropriate candidate for medical applications such as wound healing and cancer therapy, especially in HT29 treatment.