RESUMEN
The field of nanophotonics has advanced and can be utilized as a method to detect different infectious diseases. The introduction of multiplex nanophotonic diagnostics has enabled the speedy and simultaneous detection of viral infections and specific biomarkers. The quick reaction times, high sensitivity, and specificity of multiplex nanophotonic diagnostics enable real-time identification of viruses without the need for nucleic acid amplification. This review presents an overview of nanophotonic tools used to identify diseases and particular biomarkers. The paper also examines possible research areas for the development of unique, cutting-edge multiplex nanophotonic diagnostics capable of concurrently detecting various diseases or biomarkers/biomolecules. Furthermore, it discusses barriers to further advancement and offers insight into anticipated trends.
Asunto(s)
Técnicas Biosensibles , Técnicas Biosensibles/métodos , Humanos , Biomarcadores , Nanotecnología/métodos , Virosis/diagnósticoRESUMEN
In line with the renewed interest in developing novel Non Linear Optical (NLO) materials, natural Lycopene's NLO Properties are reported for the first time within the scientific literature. Correlated to its 1-D conjugated π-electrons linear conformation, it is shown that natural Lycopene exhibits a significantly elevated 3rd order nonlinearity χ(3) as high as 2.65 10-6 esu, the largest value of any investigated natural phyto-compound so far, including ß-carotene. In addition to a saturable absorption, the corresponding observed self-defocusing effect in Lycopene seems to be the result of a thermal nonlinearity. The nonlinear response coupled to the observed fluorescence in the Visible spectral range points to a potential photodynamic therapy application as well as the possibility of engineering of novel hybrid Lycopene based NLO nano-materials.