RESUMEN

Background: Chronic obstructive pulmonary disease (COPD) remains one of the most prevalent pathologies in the world and is among the leading causes of mortality and morbidity, partially due to underdiagnosis. The use of clinical questionnaires to identify high-risk individuals to take them to further diagnostic procedures has emerged as a strategy to address this problem. Objective: To compare the performance of the COULD IT BE COPD, CDQ, COPD-PS, LFQ, and PUMA questionnaires for COPD diagnosis. Methods: A cross-sectional study was carried out on subjects who underwent spirometry in the third-level center. Data were collected between January 2015 and March 2020. Bivariate analysis was performed between the study variables and the presence of COPD. The area under the receiver operating characteristics curve (AUC-ROC), sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), positive likelihood ratio (LR+), and negative likelihood ratio (LR-) for each questionnaire were calculated. The AUC-ROCs were compared with the DeLong test, considering a p value <0.05 statistically significant. Results: 681 subjects met the inclusion criteria and were taken to the final analysis. The prevalence of COPD was 27.5% (187/681). The mean age of the subjects was 65.9 years (SD ± 11.79); 46.3% (315/681) were female, and 83.6% (569/681) reported respiratory symptoms. Statistically significant relationship was found for COPD diagnosis with male sex, older age, respiratory symptoms, and exposure to wood smoke (p value <0.05). The AUC-ROCs of the questionnaires were between 0.581 and 0.681. The COULD IT BE COPD questionnaire had a lower discriminatory capacity AUC-ROC of 0.581, concerning the other scores (DeLong test, p = 0.0002). Conclusion: The CDQ, COPD-PS, LFQ, PUMA, and COULD IT BE COPD questionnaires have acceptable performance for the diagnosis of COPD together with low sensitivity and specificity. Therefore, its use must be complemented with other diagnostic tests or techniques such as pulmonary function tests.

Asunto(s)

Proteínas Reguladoras de la Apoptosis , Enfermedad Pulmonar Obstructiva Crónica , Humanos , Masculino , Femenino , Anciano , Estudios Transversales , Enfermedad Pulmonar Obstructiva Crónica/diagnóstico , Enfermedad Pulmonar Obstructiva Crónica/epidemiología , Sensibilidad y Especificidad , Espirometría/métodos , Encuestas y Cuestionarios , Volumen Espiratorio Forzado

RESUMEN

INTRODUCTION: Universal adhesives provide the possibility of simplified protocols for using ceramics; however, determining the synergy of these adhesives with silanes and the possibility of replacing silanes requires extensive research. OBJECTIVE: To evaluate the influence of a universal adhesive, associated with airborne-particle abrasion, acid etching, and silane, on the bond strength of a feldspathic ceramic CAD-CAM to composite resin. MATERIALS AND METHODS: CAD-CAM feldspathic ceramic blocks were cut into 2-mm slices and were randomly divided into six groups (n = 10): A1, Single Bond Universal (SBU); A2, Adper Single Bond 2 (SB2); B1, silane + SBU; B2, silane + SB2; C1, acid etching + silane + SBU; C2, and acid etching + silane + SB2. Tygon tubes were placed and filled with composite resin. All samples were stored in distilled water at 37 °C for 24 h and then subjected to micro-shear tests. The type of failure was analyzed using a stereomicroscope. RESULTS: SBU demonstrated slightly higher adhesion values compared with SB2 in all groups; however, no significant differences were observed between the adhesives (p < 0.05). CONCLUSION: SBU was not statistically superior to the control adhesive. The use of silane prior to a universal adhesive should not yet be eliminated.