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OBJECTIVE: To investigate the presence of changes in vibration detection and pressure pain threshold in patients with burning-mouth syndrome (BMS). DESIGN OF THE STUDY: Case-control study. The sample was composed of 30 volunteers, 15 with BMS and 15 in the control group. The pressure-pain threshold (PPT) and vibration-detection threshold (VDT) were examined. The clinical evaluation was complemented with the McGill Pain Questionnaire (MPQ), Douleur Neuropathique 4 (DN4) and Beck Depression and Anxiety Inventories (BDI and BAI, respectively). RESULTS: BMS subjects showed a statistically significant higher PPT in the tongue (p = 0.002), right (p = 0.001) and left (p = 0.004) face, and a significant reduction of the VDT in the tongue (p = 0.013) and right face (p = 0.030). Significant differences were also found when comparing the PPT and the VDT of distinct anatomical areas. However, a significant interaction (group × location) was only for the PPT. BMS subjects also showed significantly higher levels of depression (p = 0.01), as measured by the BDI, compared to controls; and a significant inverse correlation between the VDT in the left face and anxiety levels was detected. CONCLUSIONS: The study of somatosensory changes in BMS and its correlations with the clinical features as well as the levels of anxiety and depression expands current understanding of the neuropathic origin and the possible contribution of psychogenic factors related to this disease.

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Although pain is a widely known phenomenon and an important clinical symptom that occurs in numerous diseases, its mechanisms are still barely understood. Owing to the scarce information concerning its pathophysiology, particularly what is involved in the transition from an acute state to a chronic condition, pain treatment is frequently unsatisfactory, therefore contributing to the amplification of the chronic pain burden. In fact, pain is an extremely complex experience that demands the recruitment of an intricate set of central nervous system components. This includes cortical and subcortical areas involved in interpretation of the general characteristics of noxious stimuli. It also comprises neural circuits that process the motivational-affective dimension of pain. Hence, the reward circuitry represents a vital element for pain experience and modulation. This review article focuses on the interpretation of the extensive data available connecting the major components of the reward circuitry to pain suffering, including the nucleus accumbens, ventral tegmental area, and the medial prefrontal cortex; with especial attention dedicated to the evaluation of neuroplastic changes affecting these structures found in chronic pain syndromes, such as migraine, trigeminal neuropathic pain, chronic back pain, and fibromyalgia.

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Objetivo: Investigar a presença de alterações na sensibilidade vibratória e à pressão, em pacientes com síndrome de ardência bucal (SAB). Desenho do estudo: Caso-controle. A amostra foi de 30 voluntários, 15 com SAB e 15 do grupo-controle. Foram estudados os limiares de sensibilidade vibratória (LDV) e de dor à pressão (LDP). A avaliação clínica foi realizada pelos questionários de dor McGill e DN4 e pelos inventários de depressão (BDI) e de ansiedade (BAI) de Beck. Resultados: Indivíduos com SAB apresentaram um aumento estatisticamente significativo do LDP na língua (p = 0.002), na face direita (p = 0.001) e na face esquerda (p = 0.004) e uma redução significativa do LDV na língua (p = 0.013) e na face direita (p = 0.030). Foram encontrados níveis de depressão significativamente maiores no grupo de pacientes com SAB (p = 0.01) e uma correlação significativa inversa entre os níveis de ansiedade e o LVD da face esquerda. Conclusões: O estudo das alterações do sistema somatossensitivo na SAB e suas correlações com aspectos clínicos e níveis de depressão e ansiedade associados, permitem uma expansão do conhecimento atual do conhecimento atual sobre a origem neuropática e presença dos fatores psicogênicos associados à essa desordem. (AU)

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OBJECTIVE: to evaluate the frequency of keratocystic odontogenic tumor (KOT) in the Oral Surgery Service (OSS) of the University Hospital Clementino Fraga Filho of the Federal University of Rio de Janeiro (HUCFF / UFRJ), with respect to recurrence rate, gender, age of recurrence and location of the injury Methods: clinical records were reviewed and histopathological reports of KOT patients of the HUCFF/UFRJ between 2002 and 2012. Patients diagnosed with KOT were divided into two groups for the occurrence of relapse: positive (n=6) and negative (n=19) Results: regarding the location, there was a predilection for the mandible. In the average age of patients in the positive group was 40.5 and the negative group, 35.53. In the distribution by gender, positive group showed equal distribution, different from that observed in the negative group, which showed a predilection for males Conclusion: KOT was the second most frequent injury in our patients, recurrence was lower among males and had the jaw as most affected location.

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