RESUMEN
Room temperature lateral p+-i-n+light-emitting diodes (LEDs) with photonic crystals embedded in the i-region were fabricated on structures with Ge(Si) self-assembled islands and their optical properties were investigated. The use of preliminary amorphization and solid phase epitaxy of the implanted p+and n+contact regions made it possible to reduce the impurity activation temperature from 800 °Ð¡-1100 °Ð¡ to 600 °Ð¡, which corresponds to the growth temperature of Ge(Si) islands. This resulted in a significant reduction of the detrimental effect of the high-temperature annealing used for diode formation on the intensity and spectral position of the luminescence signal from the islands. It was shown that significant enhancement (more than an order of magnitude) of room temperature electroluminescence of Ge(Si) islands in the spectral range of 1.3-1.55µm can be achieved due to their interaction with different modes of the photonic crystals. The measured radiation power of the obtained diodes in the spectral range of 1.3-1.55µm exceeds 50 pW at a pump current of 8 mA, which is an order of magnitude higher than the previously achieved values for micro-LEDs with Ge(Si) nanoislands. The obtained results open up new possibilities for the realization of silicon-based light emitting devices operating at telecommunication wavelengths.
RESUMEN
The article presents a methodical approach for prediction of life expectancy for people diagnosed with prostate cancer based on the kinetic theory of aging of living systems. The life expectancy is calculated by solving the differential equation for the rate of aging for three different stage of life - «normal¼ life, life with prostate cancer and life after combination therapy for prostate cancer. The mathematical model of aging for each stage of life has its own parameters identified by the statistical analysis of healthcare data from the Zharinov's databank and Rosstat CDR NES databank. The core of the methodical approach is the statistical correlation between growth rate of the prostate specific antigen level (PSA-level) or the PSA doubling time (PSA DT) before therapy, and lifespan: the higher the PSA DT is, the greater lifespan. The patients were grouped under the «fast PSA DT¼ and «slow PSA DT¼ categories. The satisfactory matching between calculations and experiment is shown. The prediction error of group life expectancy is due to the completeness and reliability of the main data source. A detailed monitoring of the basic health indicators throughout the each person life in each analyzed group is required. The absence of this particular information makes it impossible to predict the individual life expectancy.
Asunto(s)
Envejecimiento/fisiología , Esperanza de Vida , Modelos Biológicos , Antígeno Prostático Específico/metabolismo , Neoplasias de la Próstata/metabolismo , Neoplasias de la Próstata/fisiopatología , Terapia Combinada , Humanos , Cinética , Masculino , Neoplasias de la Próstata/terapia , Reproducibilidad de los ResultadosRESUMEN
The aim of the study is to assess the adequacy of model representations, accepted in the kinetic theory of aging of living systems, the analysis of the experimental data obtained on dogs and fruit flies. The work is illustrated by applying the need to develop a mathematical model of the kinetic theory of aging to describe the probability density of death, probability of death, the average duration of life of the considered biological systems in the natural conditions of existence, as well as for dogs with limited time and chronic RA-diciannove impact, and for Drosophila - high external temperature. Op-defined kinetic equation of aging and their parameters.
Asunto(s)
Envejecimiento/fisiología , Perros/fisiología , Drosophila/fisiología , Modelos Biológicos , Animales , Cinética , Longevidad/fisiología , Modelos Teóricos , Probabilidad , Temperatura , Factores de TiempoRESUMEN
The method of iterative congruence of search of parameters of kinetic mathematical model of aging of living systems according to medical statistics is developed. Its opportunities for the description of risk functions of mortality and life expectancy for the person and animals depending on environment factors are illustrated. The concept of forecasting of environmental risks--risks to population health from ecological factors of influence--is formulated.