1.
Intern Med
; 61(2): 217-221, 2022 Jan 15.
Artículo
en Inglés
| MEDLINE
| ID: mdl-34248119
RESUMEN
We herein report a case of pneumocystis pneumonia (PCP) in a 77-year-old woman with ovarian cancer who was receiving olaparib therapy. After the patient's second relapse of ovarian cancer, she was administered olaparib as maintenance therapy following successful completion of docetaxel and carboplatin therapy. On receiving olaparib, she showed symptoms of a fever and malaise. Based on laboratory and imaging findings, she was diagnosed with PCP. After treatment with corticosteroids and trimethoprim/sulfamethoxazole followed by atovaquone, the patient's general condition improved. The lymphocytopenia observed after olaparib administration may have been associated with the development of PCP.
Asunto(s)
Neoplasias Ováricas , Pneumocystis carinii , Neumonía por Pneumocystis , Anciano , Femenino , Humanos , Recurrencia Local de Neoplasia , Neoplasias Ováricas/tratamiento farmacológico , Ftalazinas/efectos adversos , Piperazinas , Neumonía por Pneumocystis/inducido químicamente , Neumonía por Pneumocystis/diagnóstico , Neumonía por Pneumocystis/tratamiento farmacológico
2.
Gastroenterology
; 152(8): 1831-1833.e4, 2017 06.
Artículo
en Inglés
| MEDLINE
| ID: mdl-28433349