RESUMEN
Hydroa vacciniforme is a rare chronic photodermatosis with onset in childhood. It is characterized by recurrent vesicles healing with scars. We report a typical case of a young, 8-year-old boy showing favorable evolution under treatment with chloroquine and a topical sunscreen.
Asunto(s)
Dermatosis Facial/patología , Hidroa Vacciniforme/patología , Niño , Enfermedades del Oído/patología , Estudios de Seguimiento , Humanos , Masculino , Enfermedades Nasales/patologíaRESUMEN
A 22-month-old boy had xanthomatous skin lesions, neurofibromatosis, and chronic granulocytic leukemia. Histologic examination of the xanthomatous skin lesions disclosed juvenile xanthogranulomas. Twenty-three previously published cases of this association are reviewed.
Asunto(s)
Leucemia Mielógena Crónica BCR-ABL Positiva/complicaciones , Neurofibromatosis 1/complicaciones , Xantogranuloma Juvenil/complicaciones , Humanos , Lactante , Interferón alfa-2 , Interferón-alfa/administración & dosificación , Interferón-alfa/uso terapéutico , Leucemia Mielógena Crónica BCR-ABL Positiva/terapia , Masculino , Neurofibromatosis 1/patología , Proteínas Recombinantes , Enfermedades de la Piel/complicaciones , Enfermedades de la Piel/patología , Xantogranuloma Juvenil/patologíaRESUMEN
The treatment of condyloma acuminatum may be long and tiresome owing to frequent recurrences, and the multiple physical or chemical therapies utilized bear witness to the difficulties often encountered in trying to eradicate the lesions. CO2 laser is a therapeutic alternative with some advantages, such as minimal peripheral thermal necrosis with a lower risk of scar or stricture, haemostasis and perhaps sterilizing effect. Between 1985 and 1987, 69 patients (58 men and 11 women; mean age 29 years) treated with CO2 laser and followed up for at least 6 months without recurrence entered our study. All patients had multiple lesions located in the genital region in 32 cases, in the anal region in 22 cases and in both the genital and anal regions in 15 cases. The majority of patients (85%) had been referred to us owing to failure of previous treatments. We used the CO2 laser coupled with a hand-piece, working by continuous emission, with a power of 300 to 800 watts/sq.cm. Superficial vaporization of the area around the condyloma was systematically performed. Seventy-seven percent of the patients were treated under local anaesthesia. In 16 patients with intra-anal or profuse ano-genital lesions the first vaporization was carried out under general anaesthesia. Twenty-two patients (32%) were cured in one session and 19 (28%) in two sessions. Twenty-eight patients had several recurrences requiring repeated treatments (3 to 5 in 17 cases, 6 to 10 in 10 cases, 31 in 1 case) over a 2 to 17 months' period. No major complications, notably scarring, were observed.(ABSTRACT TRUNCATED AT 250 WORDS)
Asunto(s)
Neoplasias del Ano/cirugía , Condiloma Acuminado/cirugía , Neoplasias de los Genitales Femeninos/cirugía , Neoplasias de los Genitales Masculinos/cirugía , Terapia por Láser , Adulto , Femenino , Estudios de Seguimiento , Humanos , Masculino , Persona de Mediana Edad , RecurrenciaRESUMEN
A case is reported of a 70-year-old woman with chronic meningococcemia. She had intermittent fever, purpuric papules disseminated on the trunk and limbs, headache, arthralgia and myalgia for 5 weeks. Treatment with ceftriaxone was rapidly successful.
Asunto(s)
Infecciones Meningocócicas , Neisseria meningitidis , Sepsis , Anciano , Ceftriaxona/uso terapéutico , Enfermedad Crónica , Femenino , Humanos , RecurrenciaAsunto(s)
Síndrome de Inmunodeficiencia Adquirida/epidemiología , Enfermedades de Transmisión Sexual/epidemiología , Síndrome de Inmunodeficiencia Adquirida/complicaciones , Humanos , Enfermedades de Transmisión Sexual/complicaciones , Enfermedades de Transmisión Sexual/tratamiento farmacológico , Suiza , Infecciones Tumorales por Virus/complicaciones , Infecciones Tumorales por Virus/epidemiologíaRESUMEN
Direct identification of Chlamydia trachomatis with fluorescent monoclonal antibodies in smears was recently introduced for a rapid diagnosis of lower urogenital tract infections. In the present study the performance of this method was compared with that of the classical cell culture procedure with McCoy cells and iodine staining on 880 clinical specimens (table I). One hundred and twenty specimens in which one of the two methods failed for technical reasons are therefore not available for comparison. Among the remaining 760 specimens there was agreement between the two methods in 724 (95 p. 100). The sensitivity of direct identification was 85 p. 100, its specificity 97 p. 100 (table II). Our results are comparable to those reported in the literature and confirm that direct identification of Chlamydia trachomatis with fluorescent monoclonal antibodies is a useful, reasonably sensitive method for rapid diagnosis of this infection. Failures, which are relatively frequent (8 p. 100 in our series), are mostly due to inadequate specimen collection, the smears containing no epithelial cell.