RESUMEN
Fifty apparently healthy island dogs presenting to the Ross University School of Veterinary Medicine (RUSVM), St. Kitts, West Indies for neutering were used in this prospective study. Twelve of the dogs (24%) were diagnosed with spirocercosis based on a positive fecal analysis and characteristic lesions seen during esophagoscopy. Routine thoracic survey radiographs revealed changes previously reported with spirocercosis in 10/12 (sensitivity=83%) infected dogs, but in none of the uninfected dogs (38/38; specificity=100%). The most common radiographic changes were an increased fluid density within the caudal dorsal thorax on the lateral view and a widening and/or bulging of the caudal mediastinum on the dorsoventral view. After oral administration of barium sulfate, barium retention or a tortuous esophagus was visible in all infected dogs (12/12; sensitivity 100%) and in one uninfected dog (1/38; specificity 97%). The results show spirocercosis is common on St. Kitts and that radiographs are as dependable as fecal analysis and/or endoscopy in diagnosing the condition.
Asunto(s)
Enfermedades de los Perros/diagnóstico por imagen , Radiografía Torácica/veterinaria , Infecciones por Spirurida/veterinaria , Thelazioidea/aislamiento & purificación , Animales , Diagnóstico Diferencial , Enfermedades de los Perros/diagnóstico , Enfermedades de los Perros/epidemiología , Perros , Heces/parasitología , Femenino , Masculino , Estudios Prospectivos , Radiografía Torácica/normas , San Kitts y Nevis/epidemiología , Sensibilidad y Especificidad , Infecciones por Spirurida/diagnóstico , Infecciones por Spirurida/diagnóstico por imagen , Infecciones por Spirurida/epidemiologíaAsunto(s)
Cresoles/envenenamiento , Brotes de Enfermedades/epidemiología , Parálisis/inducido químicamente , Extractos Vegetales/envenenamiento , Tritolilfosfatos/envenenamiento , Bebidas/efectos adversos , Brotes de Enfermedades/historia , Contaminación de Medicamentos , Historia del Siglo XX , Humanos , Jamaica , Legislación de Medicamentos , Parálisis/epidemiología , Parálisis/historiaRESUMEN
In 1930, thousands of Americans were poisoned by an illicit extract of Jamaica ginger ("jake") used to circumvent the Prohibition laws. A neurotoxic organophosphate compound, triorthocresyl phosphate (TOCP), had been used as an adulterant. The earliest reports were of peripheral neuritis, but later it was evident that an upper motor neuron syndrome had supervened. This TOCP poisoning apparently involved various cell groups and tracts in the spinal cord; the lesions was not peripheral at all. We interviewed 11 survivors of the illness residing in eastern Tennessee. Four were carefully examined. The principal findings showed the spasticity and abnormal reflexes of an upper motor neuron syndrome. One patient had mild disease, despite typical findings, and had lived a normal life.