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OBJECTIVE: To review the clinical features, proposed pathophysiology, and the role of medical imaging in the diagnosis and treatment of idiopathic intracranial hypertension and spontaneous intracranial hypotension. METHODS: The authors conducted a narrative review of the current literature on intracranial hypertension and hypotension syndromes, with a focus on imaging findings and role of neurointerventional radiology as a therapeutic option for these pathologies. RESULTS: Idiopathic intracranial hypertension commonly presents in obese women of childbearing age, being headache and papilledema the main clinical manifestations. Characteristic radiological findings consist of increased cerebrospinal fluid around the optic nerve, partially empty sella turcica and stenosis of the transverse sinuses. Transverse sinus stenting is a treatment alternative that has proven valuable utility in the recent years. Spontaneous intracranial hypotension in most of cases presents with orthostatic headache and has predilection for female population. The typical radiological features in the brain consist of subdural fluid collections, enhancement of the dura, engorgement of the venous structures, pituitary enlargement, and sagging of the brain. In this pathology, a cerebrospinal fluid leak in the spine associated with a defect in the dura, meningeal diverticulum, or a cerebrospinal fluid-venous leak must be actively ruled out. CONCLUSIONS: Neurologic complaints secondary to changes in intracranial pressure exhibit certain clinical features that in combination with fairly specific radiological patterns allow a highly accurate diagnosis. The diverse specialists in neurosciences should be aware of the multiple image modalities in the study of these syndromes as well as the treatment alternatives by neurointerventional radiology.

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Objetivo: Análisis descriptivo de la literatura biomédica indexada en Medline entre 2001 y 2010 sobre temas relacionados con aspectos económicos (estudios de costos o evaluaciones económicas) del cáncer . Metodología: Se realizaron búsquedas en la base de datos Medline a través de GoPubMed. La est r at egi a de búsqueda f ue: ("Neoplasms" [Majr] AND ("Costs and Cost Analysis"[Majr] OR "Economics"[ Majr] OR "economics"[Subheading])) AND Journal Article[ ptyp] AND "2001:2010"[dp]. Se ident ificaron, entre otras variables, número de publicaciones por año, tipos de cáncer estudiados, revistas, países de publicación y porcentaje de publicaciones sobre temas económicos relacionadas al total de publicaciones en cáncer. Resultados: Se recuperaron 5.886 referencias que tratan sobre aspectos económicos del cáncer . La tendencia fue al incremento del número de publicaciones, con un crecimiento en diez años de 86%. Se ident ificaron 1.309 revistas diferentes, Cancer con 190 publicaciones fue la revista con más publicaciones, seguida de Journal of Clinical Oncology con 135 y Pharmacoeconomics con 76 referencias. Estados Unidos fue el país más productivo con 2.453 publicaciones (41,6%); Colombia con 8 publicaciones, fue el tercer país latinoamericano. Los cánceres más invest igados fueron seno, con 1.239; colorrectal con 753; pulmón con 516, cérvix con 477, y próstata con 403. Conclusiones: El número de publicaciones sobre literatura económica del cáncer ha crecido sostenidamente durante el periodo estudiado. Las neoplasias de los países desarrollados son las más estudiadas. [Moreno ME, Rosselli DA. Análisis bibliométrico de temas económicos en oncología. MedUNAB 2012; 14:160-166].

Objetive: Descriptive analysis of Medline-i ndexedbiomedical literature on economic aspects of cancer (mainly cost studies or economic evaluations) published between 2001 and 2010. Methods: Using GoPubMed, we searched Medline using the following search strategy: ("Neoplasms"[Majr] AND ("Costs and Cost Analysis"[Majr] OR "Economics"[Majr] OR "economics"[Subheading])) AND Journal Article[ptyp] AND "2001:2010"[dp]. We identified the number of publications per year , types of cancer considered, journals where they were published, countries and percentage of publications on economic topics of all cancer related publications. Results: We retrieved 5.886 references on economic aspects of cancer . The number of publications increased 86% in the ten-year period. We identified 1.309 different journals; Cancer, with 190 publications, was the top journal, followed by the J o u r n a l o f C l i n i c a l O n c o l o g y w i t h 1 3 5 a n dPharmacoeconomics with 76. United States was the most productive country with 2.453 publications (41.6%); Colombia with 8 references,was the third Latin American country . The top cancer site was breast, with 1.239 references; colorectal with 753; lung with 516; cervical cancer with 477, and prostate with 403. Conclusions: The number of publications on economic aspects of cancer has grown steadily over the last decade. Research has concentrated on the cancers of developed countries. Moreno ME, Rosselli DA. Bibliometric analysis of economic topics in oncology . MedUNAB 2012; 14:160-166].

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