RESUMEN

The authors report the case of a chronic myeloid leukemia (CML) patient submitted to allogenic bone marrow transplantation, who had probably never entered complete remission. The disease was reactivated as a granulocytic sarcoma, next to a platinum plate installed to correct a tibia fracture 11 years earlier. Its final event was a myeloid Ph1 + blastic crisis that was unsuccessfully treated with high doses of sc interferon and citarabine.

Asunto(s)

Humanos , Femenino , Adulto , Leucemia Mielógena Crónica BCR-ABL Positiva/terapia , Leucemia Mieloide/etiología , Trasplante de Médula Ósea/efectos adversos , Recurrencia , Trasplante Homólogo , Leucemia Mielógena Crónica BCR-ABL Positiva/etiología , Leucemia Mielógena Crónica BCR-ABL Positiva/patología , Crisis Blástica/tratamiento farmacológico , Interferones/uso terapéutico , Resultado Fatal , Citarabina/uso terapéutico , Antineoplásicos/uso terapéutico