RESUMEN
A 64-year-old women was operated on for acute abdomen and both appendiceal and ovarian tumors were found. Histology revealed synchronous adenocarcinoma of the appendix and serous pappillary carcinoma of the right ovary. The patient was given adjuvant chemotherapy and received six cycles of cisplatinum. Regular follow-up showed no recurrence of the two synchronous primary tumors. A rare case of synchronous primary tumors of appendiceal and ovarian origin is reported. The tumors proved to be difficult to treat requiring several combined medical therapies, including surgery, chemo- and radiotherapy.
Asunto(s)
Adenocarcinoma/patología , Neoplasias del Apéndice/patología , Carcinoma Papilar/patología , Neoplasias Primarias Múltiples/patología , Neoplasias Ováricas/patología , Femenino , Humanos , Persona de Mediana EdadRESUMEN
INTRODUCTION: Classical conization is a standard procedure for treatment of cervical lesions. Conization with loop diathermy is well established and lesions can be excised in more than 90% of cases. OBJECTIVE: To compare two methods of conization for the treatment of cervical dysplasia. METHOD: The study included 172 patients who had conization for diagnosed cervical dysplasia. A retrospective analysis was conducted on incidence of complications and presence of dysplasia on the specimen edges after classical conization compared to conization with loop diathermy. The possibilities for analyzing specimen edges were reviewed. RESULTS: A significantly higher incidence of complications was found among patients who underwent classical conization compared to those who had the loop diathermy procedure. The loop procedure is sufficient for treatment of cervical dysplasias. CONCLUSION: The authors suggest loop diathermy conization as the method of choice for treatment of cervical dysplasia.
Asunto(s)
Cuello del Útero/cirugía , Conización/efectos adversos , Electrocoagulación/efectos adversos , Displasia del Cuello del Útero/cirugía , Neoplasias del Cuello Uterino/cirugía , Conización/métodos , Femenino , Humanos , Estudios RetrospectivosRESUMEN
OBJECTIVES: To determine five-year survival rate and prognostic factors for patients who underwent radical surgery for carcinoma of the vulva. MATERIAL AND METHOD: 94 women were operated on from 1989 to 1996 at the Clinical Centre of Serbia. RESULTS: Five-year survival was 78.56% for Stage I, 73.5% for Stage II, for Stage III--14.28%, and for Stage IV--7.14%. Five-year survival rate for tumor size between 2 cm and 5 cm was 57.14%, and for tumors larger than 5 cm, 28.57%. Five-year survival rate was 64.28% if no lymph nodes were involved, 21.43% if there were unilateral metastatic lymph nodes and 14.28% if bilateral lymph nodes had metastatic disease. Histologic grades of the tumor showed that for grade 1, five-year survival was 64.28%, for grade 2, 35.71% and there were no survivors five years after surgery among patients with grade 3 tumor. CONCLUSION: FIGO stage, size of tumor, lymph node involvement and grade of tumor are significant prognostic factors for survival of patients after surgery.
Asunto(s)
Procedimientos Quirúrgicos Ginecológicos , Tasa de Supervivencia , Neoplasias de la Vulva/cirugía , Anciano , Femenino , Humanos , Metástasis Linfática , Invasividad Neoplásica , Pronóstico , Neoplasias de la Vulva/patologíaRESUMEN
The Authors determined alpha 2 macroglobulin in 50 healthy pregnant women and in 50 pregnant women with EPH gestosis, using the technique of nephelometry on the Immunochemistry Analyzer. The assays were done in blood serum of the mother and umbilical cord, urine and in the amniotic fluid of the affected patients. Serum values were expressed in gr/L, and amniotic fluid and urine values in mg/L. Significant reduction was found in the pregnant women with EPH gestosis in serum values of the mothers (healthy pregnant women 2.871 g/L +/- 1.015, with EPH gestosis 2.239 g/L +/- 1.323, p less than 0.05), and in the umbilical cord serum (healthy pregnant women 3.351 g/L +/- 0.859, affected ones 2.032 g/L +/- 0.693 g/L, p less than 0.01). The reduction was also noted in the urine values but was significant one. The importance of these determinations is presented in the discussion.