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Clin Transl Oncol ; 11(11): 760-4, 2009 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-19917540

RESUMEN

BACKGROUND: Non-melanoma skin tumours (NMSC) are one of the most frequent types of cancer, accounting for nearly one third of newly diagnosed tumours. NMSC are frequently diagnosed in elderly patients and while mortality rates are low, NMSC can be associated with significant morbidity in terms of cosmetic and functional impairment. OBJECTIVE: Surgical excision is nowadays considered the standard treatment for NMSC, although this approach might not be suitable for all the patients. Good rates of local control and cosmetic outcome are achieved by using high-dose-rate (HDR) plesiotherapy. METHODS: Nine consecutive patients with 11 NMSC were treated with custom-made moulds and HDR plesiotherapy reaching a fi nal dose of 44-48 Gy in 11-12 fractions of 4 Gy over 4 weeks. RESULTS: No local or distant relapses have been observed after a mean follow-up of 15 months (range 4-36 months). Acute toxicity was acceptable and cosmetic result was considered as excellent/good in 7 patients. CONCLUSIONS: This modality of treatment offers an alternative for those patients not candidates for surgical procedures because of medical contraindications or risk of disfigurement or functional impairment.


Asunto(s)
Neoplasias Cutáneas/radioterapia , Anciano , Anciano de 80 o más Años , Braquiterapia/métodos , Relación Dosis-Respuesta en la Radiación , Diseño de Equipo , Femenino , Humanos , Masculino , Dosificación Radioterapéutica , Radioterapia Adyuvante/efectos adversos , Radioterapia Adyuvante/métodos , Riesgo , Factores de Tiempo , Tomografía Computarizada por Rayos X/métodos , Resultado del Tratamiento
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