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1.
Glob Health Action ; 17(1): 2396636, 2024 Dec 31.
Artículo en Inglés | MEDLINE | ID: mdl-39263866

RESUMEN

BACKGROUND: Even though effective neonatal resuscitation prevents the consequences of neonatal death related to birth asphyxia, a significant portion of healthcare personnel lacked understanding or performed it inconsistently. It is critical to have a comprehensive study that demonstrates the overall level of knowledge of healthcare providers regarding neonatal resuscitation in Eastern Africa. METHODS: Articles were searched from Science Direct, JBI databases, Web of Sciences, PubMed, and Google Scholar. The primary outcome was the level of knowledge of health care providers regarding neonatal resuscitation. Data were analyzed using Stata version 18 statistical software. The overall estimates with a 95% confidence interval were estimated using a random effect model. RESULTS: In this meta-analysis study, 7916 healthcare providers were included. The overall level of knowledge on neonatal resuscitation among healthcare providers in Eastern Africa was 59% [95% CI: 48-70]. Trained health care providers (OR = 3.63, 95% CI: 2.26, 5.00), and work experience of 5 years and above (OR = 2.08, 95% CI: 1.00, 3.16) were determinants of the level of knowledge. However, the level of education and availability of equipment were found to be insignificantly associated with the level of knowledge. CONCLUSIONS: The results of this meta-analysis showed that healthcare professionals in Eastern Africa lacked sufficient knowledge about neonatal resuscitation. Having 5 years of work experience and training in neonatal resuscitation was found to be strongly associated with knowledge level. Thus, continuing education, training courses, and frequent updates on neonatal resuscitation protocols are required for healthcare professionals.


Main findings The overall level of knowledge on neonatal resuscitation among healthcare providers in Eastern Africa was 59% [95% CI: 48­70].Added knowledge This study provides cumulative evidence on the level of knowledge of healthcare providers regarding neonatal resuscitation, and there are regional disparities and inconsistent explanations of risk factors.Global health impact for policy and action There is insufficient knowledge among healthcare providers on neonatal resuscitation in Eastern Africa, which can contribute to higher rates of neonatal mortality, highlighting the urgent need for targeted policy interventions.


Asunto(s)
Conocimientos, Actitudes y Práctica en Salud , Personal de Salud , Resucitación , Humanos , Personal de Salud/educación , África Oriental , Recién Nacido , Asfixia Neonatal/terapia , Competencia Clínica
2.
Artículo en Inglés | MEDLINE | ID: mdl-38907794

RESUMEN

PURPOSE OF REVIEW: The purpose of this review is to summarize the recent literature regarding regional anesthesia (RA) techniques and outcomes for total hip arthroplasty (THA) in the face of changing surgical techniques and perioperative considerations. RECENT FINDINGS: Based on large meta-analyses, peripheral nerve blocks are indicated for THA. Each block has its own risks and benefits and data for outcomes for particular techniques are limited. New surgical techniques, improved use of multimodal analgesia, and improved ultrasound guided regional anesthetics lead to better pain control for patients undergoing THA with less associated risks. Block selection continues to be influenced by provider comfort, surgical approach, patient anatomy, and postoperative goals. Head-to-head studies of particular nerve blocks are warranted.

5.
Pharm Biol ; 48(1): 76-80, 2010 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-20645759

RESUMEN

The present study investigates the direct effects of Carum carvi L. (Apiaceae) ethanol extract on dispersed intestinal smooth muscle cells (SMC) of guinea pigs. Effects of the plant extract on SMC and of acetylcholine (Ach) on extract pretreated SMC were measured by micrometric scanning technique. Three different extract concentrations (2.5 mg/mL, 250 mug/mL, and 25 mug/mL) were used. Ethanol extract of C. carvi reduced significantly the response of dispersed SMC to Ach. Pretreatment of SMC with the highest concentration of C. carvi ethanol extract (2.5 mg/mL) has significantly inhibited the response of SMC to Ach. The data obtained indicate a dose-dependent inhibition of the contraction induced by Ach. This response may explain, in part, the beneficial effect of caraway in relieving gastrointestinal symptoms associated with dyspepsia.


Asunto(s)
Carum , Etanol/farmacología , Intestino Delgado/efectos de los fármacos , Relajación Muscular/efectos de los fármacos , Miocitos del Músculo Liso/efectos de los fármacos , Extractos Vegetales/farmacología , Animales , Femenino , Cobayas , Intestino Delgado/citología , Intestino Delgado/fisiología , Masculino , Relajación Muscular/fisiología , Miocitos del Músculo Liso/citología , Miocitos del Músculo Liso/fisiología , Extractos Vegetales/aislamiento & purificación
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