RESUMEN
This cross-sectional study investigated the mediatory role of experiential avoidance in the relationship between perceived stress and alexithymia with mental health. We enrolled 440 students (age 18-30 years) at Kermanshah University of Medical Sciences through stratified random sampling method. The study tools were demographic checklist, GHQ-28, Toronto Alexithymia Scale-20 and Perceived Stress Scale. Data were analysed by SPSS-18 and AMOS-18 using Pearson correlation, hierarchical regression analysis and structural equation modelling (SEM). There was a significant positive correlation between perceived stress and experiential avoidance, and alexithymia and mental health problems (P < 0.001). SEM showed that the relationship between perceived stress and mental health problems by experiential avoidance was 0.19 [(ß = 0.19; standard error (SE) = 0.09; P = 0.001], and the relationship between alexithymia and mental health problems through experiential avoidance was 0.09 (ß = 0.09; SE = 0.43; P = 0.01). The mediatory role of experiential avoidance was confirmed in such a way that the effects of alexithymia and perceived stress decreased.
Asunto(s)
Síntomas Afectivos/epidemiología , Reacción de Prevención , Salud Mental/estadística & datos numéricos , Estrés Psicológico/epidemiología , Adolescente , Adulto , Estudios Transversales , Femenino , Humanos , Irán/epidemiología , Masculino , Ahorros Médicos , Percepción , Factores Socioeconómicos , Adulto JovenRESUMEN
This cross-sectional study investigated the mediatory role of experiential avoidance in the relationship between perceived stress and alexithymia with mental health. We enrolled 440 students [age 18-30 years] at Kermanshah University of Medical Sciences through stratified random sampling method. The study tools were demographic checklist, GHQ-28, Toronto Alexithymia Scale-20 and Perceived Stress Scale. Data were analysed by SPSS-18 and AMOS-18 using Pearson correlation, hierarchical regression analysis and structural equation modelling [SEM]. There was a significant positive correlation between perceived stress and experiential avoidance, and alexithymia and mental health problems [P < 0.001]. SEM showed that the relationship between perceived stress and mental health problems by experiential avoidance was 0.19 [[beta = 0.19; standard error [SE] = 0.09; P = 0.001], and the relationship between alexithymia and mental health problems through experiential avoidance was 0.09 [beta = 0.09; SE = 0.43; P = 0.01]. The mediatory role of experiential avoidance was confirmed in such a way that the effects of alexithymia and perceived stress decreased
La présente étude transversale a examiné le rôle de médiation de l'évitement expérientiel dans le rapport entre le stress perçu, l'alexithymie et la santé mentale. Nous avons inscrit dans cette étude 440 étudiants [âge compris entre 18 et 30 ans] de l'Université des Sciences médicales de Kermanshah par la méthode d'échantillonnage aléatoire stratifié. Les instruments utilisés dans l'étude étaient la liste de contrôle démographique, le questionnaire sur la santé générale en 28 items, l'échelle d'Alexithymie de Toronto à 20 items et l'échelle de mesure du stress perçu. Les données ont été analysées au moyen des logiciels SPSS-18 et AMOS-18 en recourant à la corrélation de Pearson, l'analyse de régression hiérarchique et la modélisation par équation structurelle. Il y avait une corrélation positive significative entre le stress perçu et l'évitement expérientiel, et l'alexithymie et les problèmes de santé mentale [p<0,001]. La modélisation par équation structurelle a montré que la relation entre le stress perçu et les problèmes de santé mentale causés par l'évitement expérientiel était 0,19 [[beta =0,19; erreur standard [ES]=0,09 ; p=0,001], et que la relation entre l'alexithymie et les problèmes de santé mentale causés par l'évitement expérientiel était 0,09 [[beta =0,09; ES=0,43; p=0,001.] Le rôle de médiation de l'évitement expérientiel a été confirmé de telle sorte que les effets de l'alexithymie et du stress perçu diminuent
Asunto(s)
Enfermedades no Transmisibles , Trastornos de la Personalidad , Salud Mental , Síntomas Afectivos , Estudios Transversales , Análisis de Regresión , Estrés PsicológicoRESUMEN
Cysteine-rich receptor-like kinases (CRKs) are transmembrane proteins characterized by the presence of two domains of unknown function 26 (DUF26) in their ectodomain. The CRKs form one of the largest groups of receptor-like protein kinases in plants, but their biological functions have so far remained largely uncharacterized. We conducted a large-scale phenotyping approach of a nearly complete crk T-DNA insertion line collection showing that CRKs control important aspects of plant development and stress adaptation in response to biotic and abiotic stimuli in a non-redundant fashion. In particular, the analysis of reactive oxygen species (ROS)-related stress responses, such as regulation of the stomatal aperture, suggests that CRKs participate in ROS/redox signalling and sensing. CRKs play general and fine-tuning roles in the regulation of stomatal closure induced by microbial and abiotic cues. Despite their great number and high similarity, large-scale phenotyping identified specific functions in diverse processes for many CRKs and indicated that CRK2 and CRK5 play predominant roles in growth regulation and stress adaptation, respectively. As a whole, the CRKs contribute to specificity in ROS signalling. Individual CRKs control distinct responses in an antagonistic fashion suggesting future potential for using CRKs in genetic approaches to improve plant performance and stress tolerance.
Asunto(s)
Adaptación Fisiológica/genética , Proteínas de Arabidopsis/metabolismo , Arabidopsis/genética , Estrés Oxidativo/inmunología , Proteínas Serina-Treonina Quinasas/metabolismo , Arabidopsis/enzimología , Arabidopsis/inmunología , Proteínas de Arabidopsis/genética , Ascomicetos/inmunología , ADN Bacteriano/genética , Regulación de la Expresión Génica de las Plantas , Enfermedades de las Plantas/inmunología , Enfermedades de las Plantas/microbiología , Proteínas Serina-Treonina Quinasas/genética , Pseudomonas syringae/inmunología , Especies Reactivas de Oxígeno/metabolismo , Transducción de Señal/genética , Xantina Oxidasa/metabolismoRESUMEN
The discovery of cytosolic ABA receptors is an important breakthrough in stomatal research; signaling via these receptors is involved in determining the basal stomatal conductance and stomatal responsiveness. However, the source of ABA in guard cells is still not fully understood. The level of ABA increases in guard cells by de novo synthesis, recycling from inactive conjugates via ß-glucosidases BG1 and BG2 and by import, whereas it decreases by hydroxylation, conjugation, and export. ABA importers include the NRT1/PTR family protein AIT1, ATP-binding cassette protein ABCG40, and possibly ABCG22, whereas the DTX family member DTX50 and ABCG25 function as ABA exporters. Here, we review the proteins involved in ABA transport and homeostasis and their physiological role in stomatal regulation. Recent experiments suggest that functional redundancy probably exists among ABA transporters between vasculature and guard cells and ABA recycling proteins, as stomatal functioning remained intact in abcg22, abcg25, abcg40, ait1, and bg1bg2 mutants. Only the initial response to reduced air humidity was significantly delayed in abcg22. Considering the reports showing autonomous ABA synthesis in guard cells, we discuss that rapid stomatal responses to atmospheric factors might depend primarily on guard cell-synthesized ABA, whereas in the case of long-term soil water deficit, ABA synthesized in the vasculature might have a significant role.