RESUMEN
Drug-induced acute pancreatitis (AP) accounts for approximately 2% of acute pancreatitis. Its incidence is increasing, with more than 260 incriminated drugs. However, very few cases have been described in the literature due to accountability problem. We report our experience with 10 cases whose data were collected over a period of 7 years. Clinical presentation of AP was often equivocal. Ranson's score ranged from 0 to 5. We recorded 5 cases of edematous pancreatitis and 5 cases of necro-bleeding pancreatitis. These pancreatitis were often successfully treated without recurrence after discontinuation of the incriminated drug.
Asunto(s)
Edema/inducido químicamente , Pancreatitis Aguda Necrotizante/inducido químicamente , Pancreatitis/inducido químicamente , Enfermedad Aguda , Edema/patología , Humanos , Pancreatitis/patología , Pancreatitis Aguda Necrotizante/patología , Estudios RetrospectivosAsunto(s)
Tumores del Estroma Gastrointestinal/complicaciones , Hemoperitoneo/etiología , Neoplasias del Íleon/complicaciones , Anciano de 80 o más Años , Tumores del Estroma Gastrointestinal/diagnóstico por imagen , Hemoperitoneo/diagnóstico por imagen , Humanos , Neoplasias del Íleon/diagnóstico por imagen , Masculino , Pelvis , Rotura Espontánea , Tomografía Computarizada por Rayos XRESUMEN
Gastrointestinal bleeding secondary to a rupture of an aneurysm of the hepatic artery is rare. We report a case of an 81-year-old man, who was admitted with hematemesis and melena. Gastroduodenoscopy revealed an abundant bleeding from the posterior wall of the duodenal bulb. CT-scan shoved an aneurysm arising from the hepatic artery. Ultrasound, computed tomography and angiography are the methods of choice for gastrointestinal bleeding diagnosis if endoscopy is inconclusive.
Asunto(s)
Aneurisma Roto/complicaciones , Hemorragia Gastrointestinal/etiología , Arteria Hepática/patología , Anciano , Anciano de 80 o más Años , Humanos , MasculinoRESUMEN
UNLABELLED: Gastrointestinal stromal tumor (GIST) is a new distinct entity defined as CDI 17 or c-kit positive mesenchymal tumors, originaling in gastrointestinal pacemaker cells known as interstitial cells of Cajal. This study evaluate the percentage of GIST previously diagnosed as mesenchymal tumors in our hospital during 11 years. METHODS: A total of 30 surgically resected gastrointestinal tumor specimens were collected from January 1990 to December 2000 in the pathology laboratory of la Rabta Jospital. Immunohistochemical studies were performed on these tumors with antibodies of CD 117, smooth muscle actin (SMA) and protein S-100. RESULTS: Among the 30 tumors, 26 (86.6%) were CD117 positive and were classified as gastrointestinal stromal tumors. Among the 26 GIST, SMA was positive in 11 tumors (42.3%), 6 tumors (23%) expressed protein S-100. The 4 tumors classified as non-GIST were leiomyomas with the following immunohistochemical characteristics: CD117-negative with strong SMA-positive and protein S100 negative status. CONCLUSIONS: The majority (86.6%) of mesenchymal gastrointestinal tumors were GIST, except for a smalls groups of smooth muscle tumors.
Asunto(s)
Biomarcadores de Tumor/análisis , Tumores del Estroma Gastrointestinal/diagnóstico , Proteínas Proto-Oncogénicas c-kit/análisis , Actinas/análisis , Diagnóstico Diferencial , Neoplasias Gastrointestinales/diagnóstico , Neoplasias Gastrointestinales/patología , Tumores del Estroma Gastrointestinal/patología , Humanos , Inmunohistoquímica , Leiomioma/diagnóstico , Leiomioma/patología , Estudios Retrospectivos , Proteínas S100/análisisRESUMEN
Gastric cancer is a serious disease with a high mortality rate. Early diagnosis of the disease improves its prognosis. We report two cases of early gastric cancer and we specify the clinical, endoscopic, histologic and therapeutic aspects of the disease. This study is about two female patients, respectively, 36 and 70 years old. The diagnosis of early gastric cancer was based on pathologic examination of the resected stomach. The two patients are in remission 2 years and 6 months later, respectively. The diagnosis of early gastric cancer is often made on nonspecific symptoms. Oeso-gastro-duodenoscopy shows gastric mucosal anomalies. Pathologic examination of gastric biopsies confirm the diagnosis of adenocarcinoma. Endoscopic ultrasound is essential; it specifies the submucosal infiltration and evaluates the lymph node invasion. Surgery is the primary treatment but in some cases endoscopic mucosal resection provides good long-term results. Early diagnosis of adenocarcinoma improves the prognosis of the disease, which remains poor nowadays.