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INTRODUCTION: Disturbance in naming accuracy and reaction time (RT) is one of the early symptoms of Alzheimer's disease. Naming performance can be considered a diagnostic key in the early stages of Alzheimer's disease (AD), which has remained diagnostically challenging. Although most of the studies in this field have been conducted on the naming accuracy of common nouns, others have shown that proper nouns are more sensitive for detecting the onset of AD. This study aims to compare the naming of common and proper nouns. METHOD: Eighty pictures of common and proper nouns (40 items each) were presented to 18 healthy older adults and 18 people with mild Alzheimer's disease using DMDX software on a laptop computer. The patients' responses were transcribed into a pre-designed form, and their reaction times were captured by DMDX. RESULTS: Study results indicated a significant difference in the number of errors and RTs between proper and common nouns in patients with mild Alzheimer's disease (p-value=), implying that proper nouns may be more sensitive to mild AD. Moreover, patients with mild Alzheimer's had more problems in common and proper nouns than healthy older adults. CONCLUSION: This study demonstrated that individuals with mild AD experienced greater difficulty recalling proper nouns, which were found to be more susceptible to the effects of AD.

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INTRODUCTION: Linguistic disorders are one of the common problems in Alzheimer's disease, which in recent years has been considered as one of the key parameters in the diagnosis of Alzheimer (AD). Given that changes in sentence processing and working memory and the relationship between these two activities may be a diagnostic parameter in the early and preclinical stages of AD, the present study examines the comprehension and production of sentences and working memory in AD patients and healthy aged people. METHODS: Twenty-five people with mild Alzheimer's and 25 healthy elderly people participated in the study. In this study, we used the digit span to evaluate working memory. Syntactic priming and sentence completion tasks in canonical and non-canonical conditions were used for evaluating sentence production. We administered sentence picture matching and cross-modal naming tasks to assess sentence comprehension. RESULTS: The results of the present study revealed that healthy elderly people and patients with mild Alzheimer's disease have a significant difference in comprehension of relative clause sentences (P <0.05). There was no significant difference between the two groups in comprehension of simple active, simple active with noun phrase and passive sentences (P> 0.05). They had a significant difference in auditory and visual reaction time (P <0.05). Also there was a significant difference between the two groups in syntactic priming and sentence completion tasks. However, in non-canonical condition of sentence completion, the difference between the two groups was not significant (P> 0.05). CONCLUSION: The results of the present study showed that the mean scores related to comprehension, production and working memory in people with mild Alzheimer's were lower than healthy aged people, which indicate sentence processing problems at this level of the disease. People with Alzheimer have difficulty comprehending and producing complex syntactic structures and have poorer performance in tasks that required more memory demands. It seems that the processing problems of these people are due to both working memory and language problems, which are not separate from each other and both are involved in.

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A verb as the fundamental part of a sentence is important and its retrieval consists of different cognitive stages. Additionally, verb retrieval difficulty is reported in some types of aphasia and other neurological diseases, and some psycholinguistic variables can influence the verb retrieval process. This study aimed to provide a normative database in the Persian language for 92 black and white action pictures and related verbs in two groups of young ages (20 to 40 years old) and middle ages (41 to 64 years old). A total of 150 volunteers participated in this study, and the groups had similar characteristics due to education. The pictures were normed for variables such as name agreement, familiarity, visual complexity, age of acquisition, and image agreement. Correlation coefficients were calculated values among these measures, and comparisons were made between the two age groups. The results of the comparisons between the two groups showed that name agreement and familiarities were age-dependent. The results revealed that all measures varied with age. Also, the present study provided a set of verbs and their pictures in the Persian language and normative data were obtained on the psycholinguistic variables such that it can be used for clinical practice and research in the areas of verb processing and their naming.

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In the evaluation of the nature of naming disorders, there is a rapid increase of anomia with the progression of Alzheimer's disease (AD), which is associated with whole brain atrophy. Although numerous studies have investigated this naming disorder, there is limited information on naming procedures in these patients. Reaction time (RT) is highly sensitive to dementia and provides an accurate measurement. The present study investigated the RT of each underlying level of naming in patients with mild AD and identified the nature of anomia in these patients. The study consisted of 24 healthy elderly and 22 mild AD patients who participated in experiments that were designed for evaluating each level of Levelt's model. Responses were divided into three groups of correct, false, and no-response and their RTs were calculated. The statistical analyses showed significant differences between healthy elderly and patients with mild AD in terms of access to the concept and the phonological form of the words. Moreover, significant differences in the type of responses were observed between correct and false responses of both groups. There was a significant difference between the no-response cases except in the case of lemma access for singular and plural names in other tasks. The results suggest that patients with mild AD have problems at the conceptual stage and access to the phonological form of a word.

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BACKGROUND: During speech, larynx is higher in the neck for high-pitched sounds and lower for low-pitched sounds. Patients with different problems in cervical and cervicothoracic spine use cervical orthosis to limit cervical motion. This study aimed to evaluate the effects of Minerva orthosis on larynx height in young, healthy volunteers. SUBJECTS AND METHODS: This study included 18 subjects. Acoustic measurement of frequency variability has been assessed in 3 brace conditions: (1) without brace, (2) with brace, and (3) 30 minutes after wearing the brace. RESULTS: Several statistically significant differences were found in the comparison between Minerva and 30 minutes after Minerva. CONCLUSION: When planning cervical orthosis treatment, it is important to consider the reduction in larynx height that may result from bracing for those who are already at risk of developing dysphagia and dysphonia.