RESUMEN

We assessed results after postexposure prophylaxis against measles with immunoglobulin administered intramuscularly. Children were given 0.33 mL/kg of immunoglobulin from commercially available lots containing various titers of measles antibody within 5 days after exposure. In children receiving immunoglobulin with a titer of < or =16 IU/mL, 57% had clinically evident measles. Immunoglobulin preparations with higher measles antibody titers are required.

Asunto(s)

Inmunoglobulinas/administración & dosificación , Sarampión/prevención & control , Femenino , Humanos , Inmunización Pasiva , Lactante , Masculino , Sarampión/inmunología