RESUMEN
The dynamics of indices of the carbohydrate metabolism was studied in 164 patients, suffering morbid obesity (MO) (body mass index--BMI over 40 kg/M2), before and in 6 mo after conservative and surgical treatment. In 81 patients (I group) for treatment of MO a diet and medicine "Styfimol" were used, and in 83 (II group)--bariatric operations (gastric banding or shunting). In 6 mo after the treatment in patients of both groups a trustworthy reduction of body mass and BMI was observed, including in a group I--by 5.5 kg (4.6%), and in a group II--by 35 kg (22.8%). As a consequence of this a level of insulin and a HOMA index was noted, what have had promoted a reduction of a revealing rate of glucose tolerance violation (GTV) and diabetes mellitus (DM) type II. More essential changes in carbohydrate metabolism were observed in a group II, including a rate of revealing of HGTV--by 41%, DM type II--by 75%.
Asunto(s)
Cirugía Bariátrica , Restricción Calórica , Carbohidratos de la Dieta/administración & dosificación , Gastroplastia , Obesidad Mórbida/sangre , Adulto , Glucemia/metabolismo , Índice de Masa Corporal , Femenino , Estudios de Seguimiento , Humanos , Insulina/sangre , Masculino , Obesidad Mórbida/dietoterapia , Obesidad Mórbida/fisiopatología , Obesidad Mórbida/cirugía , Pérdida de PesoRESUMEN
The erythrocyte ghosts fatty acid composition of 29 patients with essential hypertension of the II stage were investigated. The significant decrease of some saturated fatty acids as myristic, palmitic and stearic under hypertension was established. Simultaneously the percent of omega-6 arachidonic and docosatrienoic acids substantially increased. At the same time no changes in omega-3 fatty acids were observed. The possible relationship between hypercholesterolemia and erythrocyte membrane fatty acid profile under essential hypertension discussed.