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1.
Acta Cir Bras ; 29(2): 99-103, 2014 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-24604313

RESUMEN

PURPOSE: To evaluate morphological changes of the gastric stump and not resected stomach mucosa after the completion of truncal vagotomy. METHODS: Eighty male Wistar rats were divided into four groups: CT, TV, RY and RYTV. In CT group, abdominal viscera were manipulated and the abdominal cavity was closed, in TV vagal trunks were isolated and sectioned, in RY a partial Roux-en-Y gastrectomy was performed and in RYTV the vagal trunks were sectioned and a partial Roux-en-Y gastrectomy was performed. At the 54th week after surgery, the rats were euthanized. The findings were submitted to histological analyses. RESULTS: None macroscopic or histological alterations in groups TV and CT was observed. Specimens from RY and RYTV groups did not show alterations in the gastric stump mucosa. At the jejunal side of the gastroenterostomy we found shallow ulcerative lesions always single, well-defined and with variable diameter 3 to 6 mm, six times in the RY group and none in the RYTV group (RY>RYTV, p=0.008). Neoplastic or preneoplastic lesions were not diagnosed in all groups. CONCLUSION: Truncal vagotomy is a safe and non-carcinogenic method in not resected and partially resected stomach.


Asunto(s)
Mucosa Gástrica/patología , Muñón Gástrico/patología , Estómago/patología , Vagotomía Troncal/métodos , Anastomosis en-Y de Roux/métodos , Animales , Gastroenterostomía/métodos , Yeyuno/patología , Yeyuno/cirugía , Masculino , Ilustración Médica , Modelos Animales , Ratas , Ratas Wistar , Reproducibilidad de los Resultados , Estómago/cirugía
2.
Acta Cir Bras ; 29(2): 118-24, 2014 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-24604316

RESUMEN

PURPOSE: To investigate the effects of alloxan diabetes on the abdominal wall healing of rats undergoing laparotomy. METHODS: Ninety-six male Wistar rats weighing between 200 and 300 grams, divided into two groups: non-diabetic group (G1) and another with untreated diabetes (G2). Three months after diabetes induction, the animals underwent a 5cm-long- laparotomy and 5.0 nylon monofilament suture. After the surgery, 12 animals from each group were euthanized on days 4, 14, 21 and 30 corresponding to the moments M1, M2, M3 and M4. In each moment a fragment of the abdominal wall containing the scar was removed for tensile strength measurement, histological and morphometric study. Clinical and biochemical parameters were also analyzed. RESULTS: G2 animals showed parameters compatible with severe diabetes and decreased plasma levels of insulin. The tensile strength in G2 was significantly smaller in M2 and M4, with a tendency to fall in the other two. Through light microscope, diabetic animals showed more difficulty to increase collagen density and contraction. G2 animals showed high cellularity of fibroblasts in later healing moments, with collagen thinning in M2 and M4. CONCLUSION: The abdominal wound healing in untreated diabetic animals was altered and led to a higher incidence of dehiscence and infections.


Asunto(s)
Pared Abdominal/fisiopatología , Diabetes Mellitus Experimental/fisiopatología , Resistencia a la Tracción/fisiología , Cicatrización de Heridas/fisiología , Pared Abdominal/anatomía & histología , Pared Abdominal/cirugía , Aloxano , Animales , Glucemia/análisis , Cicatriz , Colágeno/análisis , Diabetes Mellitus Experimental/inducido químicamente , Modelos Animales de Enfermedad , Fibroblastos/fisiología , Insulina/sangre , Masculino , Ratas , Ratas Wistar , Factores de Tiempo
3.
Acta cir. bras. ; 29(2): 99-103, 02/2014. graf
Artículo en Inglés | VETINDEX | ID: vti-10210

RESUMEN

To evaluate morphological changes of the gastric stump and not resected stomach mucosa after the completion of truncal vagotomy. METHODS: Eighty male Wistar rats were divided into four groups: CT, TV, RY and RYTV. In CT group, abdominal viscera were manipulated and the abdominal cavity was closed, in TV vagal trunks were isolated and sectioned, in RY a partial Roux-en-Y gastrectomy was performed and in RYTV the vagal trunks were sectioned and a partial Roux-en-Y gastrectomy was performed. At the 54th week after surgery, the rats were euthanized. The findings were submitted to histological analyses. RESULTS: None macroscopic or histological alterations in groups TV and CT was observed. Specimens from RY and RYTV groups did not show alterations in the gastric stump mucosa. At the jejunal side of the gastroenterostomy we found shallow ulcerative lesions always single, well-defined and with variable diameter 3 to 6 mm, six times in the RY group and none in the RYTV group (RY>RYTV, p=0.008). Neoplastic or preneoplastic lesions were not diagnosed in all groups. CONCLUSION: Truncal vagotomy is a safe and non-carcinogenic method in not resected and partially resected stomach.(AU)


Asunto(s)
Animales , Ratas , Estómago/anatomía & histología , Vagotomía , Mucosa Gástrica/anatomía & histología , Ratas/clasificación
4.
Acta cir. bras. ; 29(2): 118-124, 02/2014. tab, graf
Artículo en Inglés | VETINDEX | ID: vti-10206

RESUMEN

To investigate the effects of alloxan diabetes on the abdominal wall healing of rats undergoing laparotomy. METHODS: Ninety-six male Wistar rats weighing between 200 and 300 grams, divided into two groups: non-diabetic group (G1) and another with untreated diabetes (G2). Three months after diabetes induction, the animals underwent a 5cm-long- laparotomy and 5.0 nylon monofilament suture. After the surgery, 12 animals from each group were euthanized on days 4, 14, 21 and 30 corresponding to the moments M1, M2, M3 and M4. In each moment a fragment of the abdominal wall containing the scar was removed for tensile strength measurement, histological and morphometric study. Clinical and biochemical parameters were also analyzed. RESULTS: G2 animals showed parameters compatible with severe diabetes and decreased plasma levels of insulin. The tensile strength in G2 was significantly smaller in M2 and M4, with a tendency to fall in the other two. Through light microscope, diabetic animals showed more difficulty to increase collagen density and contraction. G2 animals showed high cellularity of fibroblasts in later healing moments, with collagen thinning in M2 and M4. CONCLUSION: The abdominal wound healing in untreated diabetic animals was altered and led to a higher incidence of dehiscence and infections.(AU)


Asunto(s)
Animales , Ratas , Complicaciones de la Diabetes/patología , Pared Abdominal/anatomía & histología , Resistencia a la Tracción , Alloxanum/análisis , Ratas/clasificación , Laparotomía/veterinaria
5.
Acta cir. bras ; Acta cir. bras;29(2): 99-103, 02/2014. graf
Artículo en Inglés | LILACS | ID: lil-702521

RESUMEN

To evaluate morphological changes of the gastric stump and not resected stomach mucosa after the completion of truncal vagotomy. METHODS: Eighty male Wistar rats were divided into four groups: CT, TV, RY and RYTV. In CT group, abdominal viscera were manipulated and the abdominal cavity was closed, in TV vagal trunks were isolated and sectioned, in RY a partial Roux-en-Y gastrectomy was performed and in RYTV the vagal trunks were sectioned and a partial Roux-en-Y gastrectomy was performed. At the 54th week after surgery, the rats were euthanized. The findings were submitted to histological analyses. RESULTS: None macroscopic or histological alterations in groups TV and CT was observed. Specimens from RY and RYTV groups did not show alterations in the gastric stump mucosa. At the jejunal side of the gastroenterostomy we found shallow ulcerative lesions always single, well-defined and with variable diameter 3 to 6 mm, six times in the RY group and none in the RYTV group (RY>RYTV, p=0.008). Neoplastic or preneoplastic lesions were not diagnosed in all groups. CONCLUSION: Truncal vagotomy is a safe and non-carcinogenic method in not resected and partially resected stomach.


Asunto(s)
Animales , Ratas , Estómago/anatomía & histología , Mucosa Gástrica/anatomía & histología , Vagotomía , Ratas/clasificación
6.
Acta cir. bras ; Acta cir. bras;29(2): 118-124, 02/2014. tab, graf
Artículo en Inglés | LILACS | ID: lil-702525

RESUMEN

To investigate the effects of alloxan diabetes on the abdominal wall healing of rats undergoing laparotomy. METHODS: Ninety-six male Wistar rats weighing between 200 and 300 grams, divided into two groups: non-diabetic group (G1) and another with untreated diabetes (G2). Three months after diabetes induction, the animals underwent a 5cm-long- laparotomy and 5.0 nylon monofilament suture. After the surgery, 12 animals from each group were euthanized on days 4, 14, 21 and 30 corresponding to the moments M1, M2, M3 and M4. In each moment a fragment of the abdominal wall containing the scar was removed for tensile strength measurement, histological and morphometric study. Clinical and biochemical parameters were also analyzed. RESULTS: G2 animals showed parameters compatible with severe diabetes and decreased plasma levels of insulin. The tensile strength in G2 was significantly smaller in M2 and M4, with a tendency to fall in the other two. Through light microscope, diabetic animals showed more difficulty to increase collagen density and contraction. G2 animals showed high cellularity of fibroblasts in later healing moments, with collagen thinning in M2 and M4. CONCLUSION: The abdominal wound healing in untreated diabetic animals was altered and led to a higher incidence of dehiscence and infections.


Asunto(s)
Animales , Ratas , Alloxanum/análisis , Complicaciones de la Diabetes/patología , Pared Abdominal/anatomía & histología , Resistencia a la Tracción , Laparotomía/veterinaria , Ratas/clasificación
7.
Rev. Col. Bras. Cir ; 40(6): 494-501, nov.-dez. 2013.
Artículo en Portugués | LILACS | ID: lil-702660

RESUMEN

O artigo em questão aborda os motivos pelos quais a Medicina Defensiva é largamente utilizada no Brasil e no Mundo. A Medicina Defensiva, na prática, se caracteriza pela utilização exagerada de exames complementares, pelo uso de procedimentos terapêuticos supostamente mais seguros, pelo encaminhamento frequente de pacientes a outros especialistas e pela recusa ao atendimento de pacientes graves e com maior potencial de complicações. Trata-se de uma prática que tem como objetivo principal defender o médico de eventuais processos, principalmente na área judicial. A maneira como são conduzidos os processos pelo poder judiciário certamente contribui para a consolidação desta prática insensata. A morosidade da justiça, em nosso meio, associado ao despreparo dos juízes e peritos judiciais na análise dos casos, leva a um desgaste emocional das partes. Alem disso, a formação precária do médico em nosso país faz com que se utilize de meios requintados de diagnóstico e tratamento em detrimento a um exame clínico pormenorizado e uma adequada comunicação com o paciente. Além de ineficiente em proteger o médico, a Medicina Defensiva traz consequências graves ao paciente e à sociedade, já que gera um custo adicional incalculável ao exercício da Medicina, determina um maior sofrimento ao doente e faz com que haja uma deteriorização na relação médico-paciente, que sempre foi pautada pela confiança, respeito e pessoalidade.


We discuss the reasons why Defensive Medicine is widely used in Brazil and worldwide. The Defensive Medicine is characterized by excessive use of complementary tests, the use of supposedly safer therapeutic procedures, the frequent referral of patients to other specialists and by the refusal to care for critically ill patients and with greater potential for complications. This is a practice that aims to defend the doctor from legal suits. The way the processes are conducted by the judiciary certainly contributes to the consolidation of this foolish practice. The slow pace of justice in our country, associated with the unpreparedness of judges and legal experts in the analysis of cases, leads to an emotional exhaustion of the parties involved. Furthermore, poor training of doctors in our country values the use of sophisticated diagnostic and treatment methods, rather than a thorough clinical examination and appropriate communication with the patient. Besides inefficient in protecting the doctor, Defensive Medicine has severe consequences to the patient and to society, since it generates an additional invaluable cost to medical practice, determines greater suffering to the patient and causes deterioration of the doctor-patient relationship, which has always been marked by trust, respect and personhood.


Asunto(s)
Humanos , Medicina Defensiva , Pautas de la Práctica en Medicina , Consentimiento Informado , Responsabilidad Legal
8.
Acta Cir Bras ; 28(4): 266-71, 2013 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-23568234

RESUMEN

PURPOSE: To evaluate the efficacy of surgical treatment for esophageal perforation. METHODS: A systematic review of the literature was performed. We conducted a search strategy in the main electronic databases such as PubMed, Embase and Lilacs to identify all case series. RESULTS: Thirty three case series met the inclusion criteria with a total of 1417 participants. The predominant etiology was iatrogenic (54.2%) followed by spontaneous cause (20.4%) and in 66.1% the localization was thoracic. In 65.4% and 33.4% surgical and conservative therapy, respectively, was considered the first choice. There was a statistically significance different with regards mortality rate favoring the surgical group (16.3%) versus conservative treatment (21.2%) (p<0.05). CONCLUSION: Surgical treatment was more effective and safe than conservative treatment concerning mortality rates, although the possibility of bias due to clinical and methodological heterogeneity among the included studies and the level of evidence that cannot be ruled out.


Asunto(s)
Perforación del Esófago/terapia , Esófago/cirugía , Distribución de Chi-Cuadrado , Perforación del Esófago/etiología , Perforación del Esófago/mortalidad , Perforación del Esófago/cirugía , Femenino , Humanos , Enfermedad Iatrogénica , Masculino , Persona de Mediana Edad , Resultado del Tratamiento
9.
Acta cir. bras ; Acta cir. bras;28(4): 266-271, Apr. 2013. tab
Artículo en Inglés | LILACS | ID: lil-670252

RESUMEN

PURPOSE: To evaluate the efficacy of surgical treatment for esophageal perforation. METHODS: A systematic review of the literature was performed. We conducted a search strategy in the main electronic databases such as PubMed, Embase and Lilacs to identify all case series. RESULTS: Thirty three case series met the inclusion criteria with a total of 1417 participants. The predominant etiology was iatrogenic (54.2%) followed by spontaneous cause (20.4%) and in 66.1% the localization was thoracic. In 65.4% and 33.4% surgical and conservative therapy, respectively, was considered the first choice. There was a statistically significance different with regards mortality rate favoring the surgical group (16.3%) versus conservative treatment (21.2%) (p<0.05). CONCLUSION: Surgical treatment was more effective and safe than conservative treatment concerning mortality rates, although the possibility of bias due to clinical and methodological heterogeneity among the included studies and the level of evidence that cannot be ruled out.


Asunto(s)
Femenino , Humanos , Masculino , Persona de Mediana Edad , Perforación del Esófago/terapia , Esófago/cirugía , Distribución de Chi-Cuadrado , Perforación del Esófago/etiología , Perforación del Esófago/mortalidad , Perforación del Esófago/cirugía , Enfermedad Iatrogénica , Resultado del Tratamiento
10.
Rev Col Bras Cir ; 40(6): 494-501, 2013.
Artículo en Portugués | MEDLINE | ID: mdl-24573629

RESUMEN

We discuss the reasons why Defensive Medicine is widely used in Brazil and worldwide. The Defensive Medicine is characterized by excessive use of complementary tests, the use of supposedly safer therapeutic procedures, the frequent referral of patients to other specialists and by the refusal to care for critically ill patients and with greater potential for complications. This is a practice that aims to defend the doctor from legal suits. The way the processes are conducted by the judiciary certainly contributes to the consolidation of this foolish practice. The slow pace of justice in our country, associated with the unpreparedness of judges and legal experts in the analysis of cases, leads to an emotional exhaustion of the parties involved. Furthermore, poor training of doctors in our country values the use of sophisticated diagnostic and treatment methods, rather than a thorough clinical examination and appropriate communication with the patient. Besides inefficient in protecting the doctor, Defensive Medicine has severe consequences to the patient and to society, since it generates an additional invaluable cost to medical practice, determines greater suffering to the patient and causes deterioration of the doctor-patient relationship, which has always been marked by trust, respect and personhood.


Asunto(s)
Medicina Defensiva , Pautas de la Práctica en Medicina , Humanos , Consentimiento Informado , Responsabilidad Legal
11.
In. Lopes, Ademar; Chammas, Roger; Iyeyasu, Hirofumi. Oncologia para a graduação. São Paulo, Lemar, 3; 2013. p.438-448, tab, ilus. (Oncologia para a graduação).
Monografía en Portugués | LILACS | ID: lil-692030
12.
Acta cir. bras. ; 28(4): 266-271, 2013. tab
Artículo en Inglés | VETINDEX | ID: vti-8977

RESUMEN

PURPOSE: To evaluate the efficacy of surgical treatment for esophageal perforation. METHODS: A systematic review of the literature was performed. We conducted a search strategy in the main electronic databases such as PubMed, Embase and Lilacs to identify all case series. RESULTS: Thirty three case series met the inclusion criteria with a total of 1417 participants. The predominant etiology was iatrogenic (54.2%) followed by spontaneous cause (20.4%) and in 66.1% the localization was thoracic. In 65.4% and 33.4% surgical and conservative therapy, respectively, was considered the first choice. There was a statistically significance different with regards mortality rate favoring the surgical group (16.3%) versus conservative treatment (21.2%) (p<0.05). CONCLUSION: Surgical treatment was more effective and safe than conservative treatment concerning mortality rates, although the possibility of bias due to clinical and methodological heterogeneity among the included studies and the level of evidence that cannot be ruled out.(AU)


Asunto(s)
Humanos , Animales , Neoplasias/patología , Neovascularización Patológica , Metástasis de la Neoplasia/fisiopatología , Pulmón/anatomía & histología , Ratones/parasitología
13.
Acta Cir Bras ; 27(3): 236-43, 2012 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-22460254

RESUMEN

PURPOSE: To study the effect of alcoholism on intestinal healing and postoperative complications in rats METHODS: One hundred and sixty rats were divided into two groups: control and treated. The control group received water and the treated group 30% ethanol. After 180 days, colotomy with anastomosis were performed. After, the groups were divided into four subgroups: 20 rats for study at the following moments: 4(th), 7(th), 14(th) and 21(st) postoperative. The analyzed parameters were: weight gain, breaking strength, tissue hydroxyproline, postoperative complications and histopathological study RESULTS: Weight gain was greater in the control group (p<0.05). When all the subgroups were clustered, breaking strength was significantly greater in the control (p<0.05). Histopathology and hydroxyproline dosage did not show differences. There were five surgical site infections in the treated group while the control group showed two (p>0.05). Nine fistulas occurred in the treated group whereas the control group two (p<0.05). There were three deaths in the control group and seven in the treated group (p>0.05). CONCLUSIONS: Treated group undergo a malnutrition process that is revealed by lower weight gain. Impaired intestinal healing as indicated by smaller breaking strength. There were a larger number of postoperative complications in the treated animals.


Asunto(s)
Alcoholismo/complicaciones , Colon/cirugía , Etanol/administración & dosificación , Fístula Intestinal/etiología , Peritonitis/etiología , Cicatrización de Heridas/fisiología , Anastomosis Quirúrgica/efectos adversos , Animales , Distribución de Chi-Cuadrado , Modelos Animales de Enfermedad , Desnutrición/etiología , Periodo Posoperatorio , Distribución Aleatoria , Ratas , Ratas Wistar , Dehiscencia de la Herida Operatoria/fisiopatología , Infección de la Herida Quirúrgica/etiología , Resistencia a la Tracción/fisiología , Aumento de Peso/fisiología
14.
Acta cir. bras ; Acta cir. bras;27(3): 236-243, Mar. 2012. ilus, graf, tab
Artículo en Inglés | LILACS | ID: lil-617963

RESUMEN

PURPOSE: To study the effect of alcoholism on intestinal healing and postoperative complications in rats METHODS: One hundred and sixty rats were divided into two groups: control and treated. The control group received water and the treated group 30 percent ethanol. After 180 days, colotomy with anastomosis were performed. After, the groups were divided into four subgroups: 20 rats for study at the following moments: 4th, 7th, 14th and 21st postoperative. The analyzed parameters were: weight gain, breaking strength, tissue hydroxyproline, postoperative complications and histopathological study RESULTS: Weight gain was greater in the control group (p<0.05). When all the subgroups were clustered, breaking strength was significantly greater in the control (p<0.05). Histopathology and hydroxyproline dosage did not show differences. There were five surgical site infections in the treated group while the control group showed two (p>0.05). Nine fistulas occurred in the treated group whereas the control group two (p<0.05). There were three deaths in the control group and seven in the treated group (p>0.05). CONCLUSIONS: Treated group undergo a malnutrition process that is revealed by lower weight gain. Impaired intestinal healing as indicated by smaller breaking strength. There were a larger number of postoperative complications in the treated animals.


OBJETIVO: Estudar o efeito do alcoolismo no processo de cicatrização intestinal e suas complicações pós-operatórias em ratos. MÉTODOS: Cento e sessenta ratos foram divididos em dois grupos: tratado e controle. O controle recebeu água, enquanto o tratado etanol a 30 por cento. Após 180 dias foram realizadas colotomia, seguida de anastomose. Após os animais foram divididos em quatro subgrupos de 20 ratos para estudo nos seguintes momentos: 4º, 7º, 14º e 21º pós-operatório. Os parâmetros analisados foram: ganho de peso, força de ruptura, hidroxiprolina tecidual, complicações pós-operatórias e estudo histopatológico. RESULTADOS: O ganho de peso foi superior no grupo controle (p<0,05). Após agrupamento dos momentos a força de ruptura foi superior no controle (p<0,05). Não houve diferença quanto à histopatologia e hidroxiprolina. Houve cinco infecções de incisão no grupo tratado, enquanto no controle ocorreram duas (p>0,05). Houve nove fístulas no grupo tratado, enquanto no controle duas (p<0,05). Ocorreram sete mortes no grupo tratado e apenas três no controle (p>0,05). CONCLUSÕES: No grupo tratado ocorreu um processo de subnutrição evidenciado pelo menor ganho de peso. Piora na cicatrização intestinal, indicada pela menor força de ruptura. Ocorreu um maior número de complicações pós-operatórias no grupo tratado.


Asunto(s)
Animales , Ratas , Alcoholismo/complicaciones , Colon/cirugía , Etanol/administración & dosificación , Fístula Intestinal/etiología , Peritonitis/etiología , Cicatrización de Heridas/fisiología , Anastomosis Quirúrgica/efectos adversos , Distribución de Chi-Cuadrado , Modelos Animales de Enfermedad , Desnutrición/etiología , Periodo Posoperatorio , Distribución Aleatoria , Ratas Wistar , Dehiscencia de la Herida Operatoria/fisiopatología , Infección de la Herida Quirúrgica/etiología , Resistencia a la Tracción/fisiología , Aumento de Peso/fisiología
15.
Acta cir. bras. ; 27(3): 236-243, 2012. ilus, graf, tab
Artículo en Inglés | VETINDEX | ID: vti-3981

RESUMEN

PURPOSE: To study the effect of alcoholism on intestinal healing and postoperative complications in rats METHODS: One hundred and sixty rats were divided into two groups: control and treated. The control group received water and the treated group 30 percent ethanol. After 180 days, colotomy with anastomosis were performed. After, the groups were divided into four subgroups: 20 rats for study at the following moments: 4th, 7th, 14th and 21st postoperative. The analyzed parameters were: weight gain, breaking strength, tissue hydroxyproline, postoperative complications and histopathological study RESULTS: Weight gain was greater in the control group (p<0.05). When all the subgroups were clustered, breaking strength was significantly greater in the control (p<0.05). Histopathology and hydroxyproline dosage did not show differences. There were five surgical site infections in the treated group while the control group showed two (p>0.05). Nine fistulas occurred in the treated group whereas the control group two (p<0.05). There were three deaths in the control group and seven in the treated group (p>0.05). CONCLUSIONS: Treated group undergo a malnutrition process that is revealed by lower weight gain. Impaired intestinal healing as indicated by smaller breaking strength. There were a larger number of postoperative complications in the treated animals.(AU)


OBJETIVO: Estudar o efeito do alcoolismo no processo de cicatrização intestinal e suas complicações pós-operatórias em ratos. MÉTODOS: Cento e sessenta ratos foram divididos em dois grupos: tratado e controle. O controle recebeu água, enquanto o tratado etanol a 30 por cento. Após 180 dias foram realizadas colotomia, seguida de anastomose. Após os animais foram divididos em quatro subgrupos de 20 ratos para estudo nos seguintes momentos: 4º, 7º, 14º e 21º pós-operatório. Os parâmetros analisados foram: ganho de peso, força de ruptura, hidroxiprolina tecidual, complicações pós-operatórias e estudo histopatológico. RESULTADOS: O ganho de peso foi superior no grupo controle (p<0,05). Após agrupamento dos momentos a força de ruptura foi superior no controle (p<0,05). Não houve diferença quanto à histopatologia e hidroxiprolina. Houve cinco infecções de incisão no grupo tratado, enquanto no controle ocorreram duas (p>0,05). Houve nove fístulas no grupo tratado, enquanto no controle duas (p<0,05). Ocorreram sete mortes no grupo tratado e apenas três no controle (p>0,05). CONCLUSÕES: No grupo tratado ocorreu um processo de subnutrição evidenciado pelo menor ganho de peso. Piora na cicatrização intestinal, indicada pela menor força de ruptura. Ocorreu um maior número de complicações pós-operatórias no grupo tratado.(AU)


Asunto(s)
Animales , Ratas/clasificación , Cicatrización de Heridas/fisiología , Intestinos/anatomía & histología , Alcoholismo/complicaciones , Etanol/administración & dosificación , Hidroxiprolina/biosíntesis
16.
Rev Col Bras Cir ; 38(3): 198-201, 2011.
Artículo en Portugués | MEDLINE | ID: mdl-21789460

RESUMEN

This is an article that talks about the real importance of Informed Consent (IC) in medical practice. This document has been increasingly used as a defensive practice, in order to provide evidence to the defense of any lawsuit of medical responsibility, thus distorting the original idea, which would be to respect patient autonomy and delimit medical liability. The document aims to show that the doctor complied with his duty to inform. Its great value lies in cases where there is a risk of irreversible damage to the patient. We conclude, however, that a well-documented chart, which includes the recording of information that was provided and the degree of participation of patients and their families in treatment decisions, should also have legal and ethical value similar to the IC's.


Asunto(s)
Consentimiento Informado , Ética Médica , Humanos
17.
Rev. Col. Bras. Cir ; 38(3): 198-201, maio-jun. 2011.
Artículo en Portugués | LILACS | ID: lil-593973

RESUMEN

Trata-se de um artigo que comenta sobre a real importância do Termo de Consentimento Informado na prática médica. Este documento tem sido cada vez mais usado como uma prática defensiva, a fim de constituir provas para defesa de um eventual processo judicial de responsabilidade médica, desvirtuando assim a idéia original, que seria a de respeitar a autonomia do paciente e delimitar a responsabilidade médica. O documento tem como objetivo mostrar que o médico cumpriu com seu dever de informar. Seu grande valor reside nos casos onde existam riscos de danos irreversíveis ao paciente. Conclui-se, porém, que um prontuário bem elaborado onde se inclui o registro das informações que foram transmitidas, bem como o grau de participação dos pacientes e seus familiares nas decisões terapêuticas, também deve ter valor ético e jurídico semelhante do TCI.


This is an article that talks about the real importance of Informed Consent (IC) in medical practice. This document has been increasingly used as a defensive practice, in order to provide evidence to the defense of any lawsuit of medical responsibility, thus distorting the original idea, which would be to respect patient autonomy and delimit medical liability. The document aims to show that the doctor complied with his duty to inform. Its great value lies in cases where there is a risk of irreversible damage to the patient. We conclude, however, that a well-documented chart, which includes the recording of information that was provided and the degree of participation of patients and their families in treatment decisions, should also have legal and ethical value similar to the IC's.


Asunto(s)
Humanos , Consentimiento Informado , Ética Médica
18.
Rev Col Bras Cir ; 38(1): 59-65, 2011.
Artículo en Portugués | MEDLINE | ID: mdl-21537745

RESUMEN

Chronic groin pain after herniorrhaphy is a concern, as approximately 10% of patients undergoing inguinal hernia repair have symptoms, which often limit physical ability. The etiopathogenesis is related to periostitis pubis (somatic pain) and more often to nerve injury (neuropathic pain). It is clinically important to distinguish between these two types of pain because treatment can be different. The physician should establish a routine diagnosis and treatment, and most patients will need surgical approach. Prevention of this condition is of great importance and can lead to a lower incidence of the syndrome. Some measures are key, such as how to avoid application of stitches or clips to the pubis periosteum, using the prosthesis carefully and identifying the nerves in the groin. This last measure is certainly the most important in the prevention of chronic pain and involves thorough knowledge of anatomy and the use of refined technique.


Asunto(s)
Hernia Inguinal/cirugía , Dolor , Complicaciones Posoperatorias , Algoritmos , Enfermedad Crónica , Ingle , Humanos , Dolor/diagnóstico , Dolor/etiología , Manejo del Dolor , Complicaciones Posoperatorias/diagnóstico , Complicaciones Posoperatorias/etiología , Complicaciones Posoperatorias/terapia
19.
Rev. Col. Bras. Cir ; 38(1): 59-65, jan.-fev. 2011. ilus
Artículo en Portugués | LILACS | ID: lil-584129

RESUMEN

A dor inguinal crônica pós-herniorrafia é uma situação preocupante, pois aproximadamente 10 por cento dos pacientes submetidos à hernioplastia inguinal apresenta os sintomas, que com frequência limita a capacidade física. A etiopatogênese está relacionada a uma periostite do púbis (dor somática) e mais frequentemente à lesão nervosa (dor neuropática). É importante distinguir clinicamente entre os dois tipos de dor, pois o tratamento pode ser diferente. O médico deve estabelecer uma rotina diagnóstica e de tratamento, sendo que a maior parte dos pacientes necessitarão de terapêutica cirúrgica. A prevenção desta condição é de grande importância e pode levar a uma menor incidência da síndrome. Algumas medidas são fundamentais, como evitar pontos ou clipes no periósteo do púbis, usar criteriosamente as próteses e identificar os nervos da região inguinal. Esta última medida é certamente a mais importante na prevenção da dor crônica e implica em conhecimento profundo da anatomia e o uso de uma técnica aprimorada.


Chronic groin pain after herniorrhaphy is a concern, as approximately 10 percent of patients undergoing inguinal hernia repair have symptoms, which often limit physical ability. The etiopathogenesis is related to periostitis pubis (somatic pain) and more often to nerve injury (neuropathic pain). It is clinically important to distinguish between these two types of pain because treatment can be different. The physician should establish a routine diagnosis and treatment, and most patients will need surgical approach. Prevention of this condition is of great importance and can lead to a lower incidence of the syndrome. Some measures are key, such as how to avoid application of stitches or clips to the pubis periosteum, using the prosthesis carefully and identifying the nerves in the groin. This last measure is certainly the most important in the prevention of chronic pain and involves thorough knowledge of anatomy and the use of refined technique.


Asunto(s)
Humanos , Hernia Inguinal/cirugía , Dolor , Complicaciones Posoperatorias , Algoritmos , Enfermedad Crónica , Ingle , Dolor/diagnóstico , Dolor/etiología , Dolor/terapia , Complicaciones Posoperatorias/diagnóstico , Complicaciones Posoperatorias/etiología , Complicaciones Posoperatorias/terapia
20.
Acta cir. bras ; Acta cir. bras;25(5): 423-427, Sept.-Oct. 2010. tab
Artículo en Inglés | LILACS | ID: lil-558728

RESUMEN

PURPOSE: To compare two different incisional hernia repair techniques (repair with a polypropylene mesh reinforcement on the peritonium-aponeurosis versus polypropylene mesh sutured to the borders of the hernial ring as a bridge) in rabbits. METHODS: Incisional hernia was experimentally developed through a 4-cm median incision in 60 rabbits. After 30 days, half of the animals were operated for primary wall closure and placement of a polypropylene mesh reinforcement, while the other half had a polypropylene mesh sutured to the borders of the hernial ring as a bridge. Clinical development, scar breaking strength, as well as gross, microscopic and morphometric parameters were evaluated in all animals 30, 60, and 90 days after repair. RESULTS: No significant differences in breaking strength or histological parameters were observed between groups at any time point studied. No statistical difference regarding complications was detected, although denser and firmer adhesions to the abdominal wall were seen after the mesh was placed as a " bridge" . CONCLUSIONS: No significant differences between the incisional hernia repair techniques assessed were observed regarding breaking strength, and histological and morphometric parameters. The number of complications was similar in both study groups. However, adhesion of abdominal cavity organs to the scar area was much denser after the placement of a mesh to bridge the defect.


OBJETIVO: Comparar duas técnicas de tratamento da hérnia incisional em coelhos utilizando a tela de polipropileno apoiando um reforço peritônio - aponeurótico ou suturada nas bordas do anel herniário 'em ponte" . MÉTODOS: Foram operados 60 coelhos para a produção de hérnia incisional, em uma incisão mediana de 4 centímetros. Após 30 dias, metade dos animais foram operados com o fechamento primário da parede, com colocação de uma tela de polipropileno apoiando o reforço e a outra metade dos animais com a colocação da tela suturada nas bordas do anel herniário " em ponte" . Os animais foram avaliados com 30 (M1), 60 (M2)e 90 (M3) dias de pós-operatório. Os parâmetros analisados foram a evolução clínica, análise da força de ruptura da cicatriz, estudo macroscópico, análise microscópica e morfométrica. RESULTADOS: Não foram observadas diferenças significantes com relação a força de ruptura e estudos histológicos nos dois grupos e vários momentos estudados. Não houve diferença estatística com relação às complicações, embora os animais que receberam a tela " em ponte" tiveram aderências mais firmes e intensas à parede abdominal. CONCLUSÕES: As duas técnicas utilizadas para correção da hérnia incisional em coelhos não mostraram diferenças significantes quanto a força de ruptura, análise histológica e morfométrica. O número de complicações foi semelhante, porém a aderência de órgãos da cavidade abdominal à área de cicatriz foi muito mais intensa no grupo em que a tela foi colocada " em ponte" .


Asunto(s)
Animales , Masculino , Conejos , Hernia Abdominal/cirugía , Polipropilenos , Mallas Quirúrgicas , Modelos Animales de Enfermedad , Mallas Quirúrgicas/efectos adversos , Adherencias Tisulares/patología , Cicatrización de Heridas/fisiología
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