RESUMEN
Microbiological study of pharyngeal mucosa in 43 children with solid tumors revealed that 77.2% of isolated microorganisms belonged to Gram-positive flora. It was shown that streptococci and Staphylococcus aureus were the main species. Species composition of streptococci included both pyogenic (S. pyogenes, S. agalactiae, S. dysgalactiae, S. equi) andviridans species (S. acidominimus, S. oralis and "S. milleri" group). Nocardioform actinomycetes, corynebacteria and other staphylococci were referred to additional microflora. Accidental microflora was represented by Neisseria spp., non-fermenting Gram-negative bacteria, enterobacteria and yeast-like fungi. Microbiologic study of pharyngeal mucosa biocenosis showed that monoculture was present only in 2.3% of cases; in other cases microorganisms formed both intra-genus and inter-species associations. 2-6-component associations were revealed with predominance of 3-4-component associations (37.2% and 32.6% respectively). Relationship of distribution of microorganisms belonging to main and additional microflora was revealed.
Asunto(s)
Neoplasias/inmunología , Faringe/inmunología , Faringe/microbiología , Adolescente , Niño , Preescolar , Bacterias Gramnegativas/aislamiento & purificación , Bacterias Grampositivas/aislamiento & purificación , Humanos , Lactante , Membrana Mucosa/microbiología , Neoplasias/tratamiento farmacológicoRESUMEN
Physical status of 172 former cases of retroperitoneal tumors was investigated. As a result of treatment for cancer, former patients revealed changes in the urinary (62.5%), cardiovascular (25%) systems and gastrointestinal tract (71.5%). These indices, however, stayed within the morbidity rates in the total population.
Asunto(s)
Estado de Salud , Calidad de Vida , Neoplasias Retroperitoneales/fisiopatología , Neoplasias Retroperitoneales/terapia , Adolescente , Adulto , Sistema Cardiovascular/fisiopatología , Niño , Preescolar , Sistema Digestivo/fisiopatología , Femenino , Humanos , Masculino , Neoplasias Retroperitoneales/secundario , Estudios Retrospectivos , Sistema Urinario/fisiopatologíaRESUMEN
In experiments on CBA mice it was shown that erythrocytes administered at the stage of prehemolysis or the stromal fraction of erythrolysate caused an additional increase in the haemopoietic stem cell migration which had been intensified by hemorrhage or hypoxic hypoxia.
Asunto(s)
Eritrocitos/fisiopatología , Células Madre Hematopoyéticas/fisiología , Traumatismos Experimentales por Radiación/fisiopatología , Anemia/fisiopatología , Animales , Movimiento Celular , Hemólisis , Hipoxia/fisiopatología , Ratones , Ratones Endogámicos CBARESUMEN
Stimulation of erythropoiesis in rats (hemolytic-phenylhydrazine and acute posthemorrhagic anemia, effect of hypoxic hypoxia) was accompanied by an increased erythropoietine-formating activity in kidney microsomes and light mitochondria. The phenomenon correlated with an increased esterase activity in hypotonic supernatant of kidney homogenate mainly due to the enzymatic fraction, corresponding to alpha2-globulin by its mobility. Histochemical examination of kidney showed that the most distinct alterations in the esterase activity were observed in epithelial cells of nephron proximal part and in capillary endothelium.
Asunto(s)
Eritropoyetina/biosíntesis , Esterasas/metabolismo , Riñón/metabolismo , Microsomas/metabolismo , Mitocondrias/metabolismo , Anemia/enzimología , Anemia/metabolismo , Anemia Hemolítica/enzimología , Anemia Hemolítica/metabolismo , Animales , Hipoxia/enzimología , Hipoxia/metabolismo , Riñón/enzimología , Riñón/ultraestructura , Ratones , Microsomas/enzimología , Mitocondrias/enzimología , RatasRESUMEN
The authors examined the effect of apamine on rats, rabbits and guinea pigs with experimental inflammation. Apamine inhibited serotonine and dextrane oedema on the hind paw of a rat as well as the excudative reaction in inflammation, induced by Croton oil. Apamine manifested antiserotomine effect on an isolated ileum of a guinea pig. It inhibited the increase of haptoglobulin and mucoprotein in serum of animals with experimental inflammation.