RESUMEN
Resumen Objetivo: recopilar información de factores de riesgo de la enfermedad arterial coronaria en población adulta evidenciados mediante estudios de aleatorización mendeliana. Métodos: de acuerdo con las recomendaciones de la escala para la Evaluación de Artículos de Revisión Narrativa (SANRA), se realizó una revisión desde el usuario de la Universidad Militar Nueva Granada en las bases de datos de PubMed, EMBASE y BIREME. Resultados: se obtuvieron 757 artículos, luego se aplicaron los criterios de inclusión y exclusión, y se eligieron 29 artículos en los que se investiga la asociación de la enfermedad arterial coronaria con la apolipoproteína B, colesterol LDL, triglicéridos, colesterol total, apolipoproteina C3, proteína de transferencia de ésteres de colesterol, HDL, omega 6, lipoproteína (a), obesidad, hemoglobina A1C, diabetes mellitus tipo 2, glucosa en ayunas, inicio del hábito de fumar, presión arterial, hormona paratiroidea sérica, niveles de fosfato sérico, enfermedad del hígado graso no alcohólico, síndrome de ovario poliquístico, globulina fijadora de hormonas sexuales, testosterona, filoquinona circulante, proteína gla de la matriz inactiva, antioxidantes circulantes derivados de la dieta, glicina, homocisteína, ácido úrico, marcadores inflamatorios, hemoglobina, hematocrito y recuento de glóbulos rojos. Conclusión: esta revisión sugiere nuevos estudios con información genética colombiana para respaldar los factores de riesgo aquí presentados, teniendo en cuenta que en ninguno de los estudios evaluados se utilizó información genética latinoamericana, lo cual puede limitar la extrapolación de los resultados.
Summary: Objective: To compile information on risk factors for coronary artery disease in the adult population evidenced by Mendelian randomization studies.. Methods: A search was carried out from the user of the Nueva Granada Military University in the databases of PubMed, EMBASE and BIREME and a narrative review of the literature was carried out in accordance with the recommendations of the scale for the Evaluation of Narrative Review Articles (SANRA). Results: 757 articles were obtained, after the application of inclusion and exclusion criteria, 29 articles were chosen that investigated the association of apolipoprotein B, LDL cholesterol, triglycerides, total cholesterol, apolipoprotein C3, cholesterol ester transfer protein, HDL, omega 6, lipoprotein (a), obesity, hemoglobin A1C, type 2 diabetes mellitus, fasting glucose, smoking initiation, blood pressure, serum parathyroid hormone, serum phosphate levels, non-alcoholic fatty liver disease, polycystic ovary syndrome , sex hormone-binding globulin, testosterone, circulating phylloquinone, inactive matrix protein gla, circulating dietary-derived antioxidants, glycine, homocysteine, uric acid, inflammatory markers, hemoglobin, hematocrit, and red blood cell count, with coronary artery disease. Conclusion: This review suggests new studies with Colombian genetic information to support the risk factors presented here, considering that none of the studies evaluated used Latin American genetic information, which may limit the extrapolation of the results.
RESUMEN
BACKGROUND: Plant volatile organic compounds (VOCs) play a crucial role in mediating interactions between plants, herbivores and natural enemies. Among these VOCs, methyl salicylate and (E,E)-α-farnesene are emitted as herbivore-induced plant volatiles (HIPVs) by soybean plants in response to feeding by the brown stink bug Eushistus heros. These HIPVs function as synomones, influencing the foraging behaviour of the egg parasitoid, Telenomus podisi, the main natural enemy of E. heros, one of the major soybean pests in Brazil. RESULTS: Laboratory experiments showed that two soybean cultivars, BRS 7580 and BRS 7880, produced similar qualitative blends of HIPVs, with methyl salicylate, (E,E)-α-farnesene and (Z)-3-hexenyl acetate being produced by both cultivars. Soybean cultivar BRS 7580 produced a significant lower amount of HIPVs compared to BRS 7880 but this difference did not affect the attractiveness of the egg parasitoid Telenomus podisi. Field experiments using these two cultivars and synthetic applications of methyl salicylate and (E,E)-α-farnesene showed a substantial increase in egg parasitism in all treated areas. Parasitism rates ranged from 50% to 80% in areas where these HIPVs were deployed, compared to only 10% in untreated control areas. CONCLUSIONS: The egg parasitoid Telenomus podisi demonstrated an adept ability in recognising between HIPVs in soybean blends, even in the presence of significant quantitative differences. The results from the field experiment showed the potential of HIPVs in attracting natural enemies to specific target areas within fields. (E,E)-α-Farnesene showed an improved action during the later stages of soybean growth, notably at R6. In addition, this volatile attracted other families of natural enemies. © 2024 Society of Chemical Industry.
Asunto(s)
Glycine max , Heterópteros , Salicilatos , Sesquiterpenos , Avispas , Glycine max/parasitología , Animales , Heterópteros/parasitología , Heterópteros/fisiología , Avispas/fisiología , Avispas/efectos de los fármacos , Óvulo/parasitología , Óvulo/efectos de los fármacos , Control Biológico de Vectores , Compuestos Orgánicos Volátiles , Herbivoria , FemeninoRESUMEN
RESUMEN El perfeccionamiento de la técnica deportiva tiene como premisa comparar los valores del movimiento motriz, esta debe ser caracterizada para corregir errores detectados como parte del proceso de dirección del entrenamiento deportivo. Se pone énfasis en los deportes eminentemente técnicos, como es el caso del entrenamiento del fisiculturismo. En tal sentido, la presente investigación tuvo como objetivo analizar la técnica de la media sentadilla en fisiculturistas profesionales y amateurs como método empírico (medición específica del deporte). La investigación es descriptiva-explicativa de orden correlacional. Se correlacionan seis variables de interés (X1: ángulo de la articulación del hombro; X2: ángulo de la articulación de la cadera; X3: Velocidad máxima alcanzada; X4: aceleración máxima alcanzada; X5: centro de gravedad en X; X6: centro de gravedad en Y). Las medias establecen diferencias entre grupos independientes, tanto en la variable X1 (Grupo 1: ≈66°; grupo 2: H"70°; p=0.247), la X2 (grupo 1: ≈73°; grupo 2: ≈86°; p=0.002), La X3 (grupo 1:≈1.03m/s; grupo 2: ≈1.36m/s; p=0.017), la X4 (grupo 1: ≈2.93m/s2; grupo 2: ≈4.78m/s2; p=0.011), la X5 (grupo 1: ≈0.43m; grupo 2: ≈0.65m; p=0.000), y la X6 (grupo 1: ≈0.61m; grupo 2: ≈0.83m; p=0.000). El grupo 1 posee una técnica más efectiva, mientras que los amateurs poseen menor eficiencia en el movimiento biomecánico dada su inexperiencia, se muestran valores altos en velocidad y aceleración, se incluyen ángulos de movimiento como el de cadera.
RESUMO A melhoria da técnica desportiva baseia-se na premissa de comparar os valores do movimento motor, que deve ser caracterizada a fim de corrigir erros detectados como parte do processo de gestão do treino desportivo. A tónica é colocada no desporto eminentemente técnico, como é o caso do treino de musculação. Neste sentido, o objectivo desta investigação era analisar a técnica de meio agachamento em musculturistas profissionais e iniciantes como um método empírico (medição específica do desporto). A investigação é descritiva-explicativa da ordem correlativa. Seis variáveis de interesse estão correlacionadas (X1: ângulo da articulação do ombro; X2: ângulo da articulação da anca; X3: velocidade máxima alcançada; X4: aceleração máxima alcançada; X5: centro de gravidade em X; X6: centro de gravidade em Y). Os meios estabelecem diferenças entre grupos independentes, tanto na variável X1 (Grupo 1: ≈66°; grupo 2: ≈70°; p=0,247), a X2 (grupo 1: ≈73°; grupo 2: ≈86°; p=0,002), a X3 (grupo 1: ≈1. 03m/s; grupo 2: ≈1.36m/s; p=0.017), o X4 (grupo 1: ≈2.93m/s2; grupo 2: ≈4.78m/s2; p=0.011), o X5 (grupo 1: ≈0.43m; grupo 2: ≈0.65m; p=0.000), e o X6 (grupo 1: ≈0.61m; grupo 2: ≈0.83m; p=0.000). O grupo 1 tem uma técnica mais eficaz, enquanto os iniciantes têm uma eficiência de movimento biomecânico mais baixa devido à sua inexperiência, eles mostram menos eficiência no movimento biomecânico. Dada a sua inexperiência, são mostrados valores elevados em velocidade e aceleração, e são incluídos ângulos de movimento como o ângulo da anca.
ABSTRACT The improvement of the sports technique is premised on comparing the values of the motor movement, this must be characterized to correct errors detected as part of the sports training management process. Emphasis is placed on highly technical sports, such as bodybuilding training. In this sense, the present research aimed to analyze the half-squat technique in professional and amateur bodybuilders as an empirical method (sport-specific measurement). The research is descriptive-explanatory of correlational order. Six variables of interest are correlated (X1: shoulder joint angle; X2: hip joint angle; X3: maximum speed reached; X4: maximum acceleration reached; X5: center of gravity in X; X6: center of gravity in Y). The means establish differences between independent groups, both in variable X1 (group 1: ≈66°; group 2: ≈70°; p=0.247 ), X2 (group 1: ≈73°; group 2: ≈86°; p=0.002 ), X3 (group 1: ≈1.03m/s; group 2:≈1.36m/s; p=0.017 ), X4 (group 1: ≈2.93m/s2; group 2: ≈4.78m/s2; p=0.011 ), X5 (group 1: ≈0.43m; group 2:≈0.65m; p=0.000 ), and X6 (group 1: ≈0.61m; group 2: ≈0.83m; p =0.000 ). Group 1 has a more effective technique, while the amateurs have less efficiency in biomechanical movement due to their inexperience, high values are shown in speed and acceleration, movement angles such as hip angles are included.
RESUMEN
Beagles are less susceptible to Rhipicephalus sanguineus sensu lato tick due to the production of the allomones benzaldehyde and 2-hexanone. Our previous published work showed that these compounds can reduce tick burden on susceptible dogs. Here we tested the hypothesis that an increase in repellent dose and release rate could increase repellent efficacy and persistence. Slow-release formulations of these compounds, with higher doses and release rates, were tested on artificially-infested dogs. Ten dogs were randomly assigned to two groups with five dogs each. The treated group received collars with slow-release formulations of the compounds attached, while the control group received collars with clean formulations attached. Five environmental infestations were performed, with the number of ticks (at all stages) on the dogs being counted once a day for 40 days. No significant increase in repellent efficacy was observed with the higher doses and release rates, whereas a greater persistence in repellent activity was observed. Treatment with the formulations resulted in a two-to-three-fold reduction in the number of immature stage ticks for up to three weeks. However, the number of adults was similar in both groups. Loss of repellent activity after the third week of testing coincided with a marked change in the relative release rates for the two compounds. It is hypothesized that relative amounts, rather than absolute amounts, of repellent release from slow-release formulations are important for repellent activity. We also hypothesize that the avoidance of less-preferred hosts by ticks relies on olfactory-mediated perception of specific blends of volatile cues from less preferred hosts.(AU)
Beagles são menos suscetíveis ao carrapato Rhipicephalus sanguineus sensu lato devido à produção de benzaldeído e 2-hexanona. Nosso trabalho anterior já publicado mostrou que esses compostos podem reduzir a carga de carrapatos em cães suscetíveis. Aqui testamos a hipótese de que um aumento na dose destes repelentes e na taxa de liberação poderia aumentar a eficácia e a persistência do efeito repelente. As formulações de liberação lenta destes compostos, com doses e taxas de liberação mais elevadas foram testadas em cães infestados artificialmente. Dez cães foram distribuídos aleatoriamente em dois grupos com cinco cães cada. O grupo tratado recebeu colares contendo formulações de liberação lenta dos compostos, enquanto o grupo controle recebeu colares com formulações limpas. Cinco infestações ambientais foram realizadas, com o número de carrapatos (em todas as fases) nos cães sendo contados, uma vez ao dia, por 40 dias. Não se observou aumento significativo na eficácia do repelente com doses e taxas de liberação mais elevadas e, enquanto observou-se maior persistência na atividade repelente. O tratamento com as formulações resultou em uma redução de duas a três vezes no número de carrapatos dos estágios imaturos, por até três semanas. No entanto, o número de adultos foi semelhante em ambos os grupos. A perda de atividade repelente após a terceira semana de teste coincidiu com uma mudança nas taxas de liberação relativa para os dois compostos. A hipótese é que as quantidades relativas, ao invés das quantidades absolutas de liberação lenta, são importantes para a atividade repelente. Então, a hipótese é de que a repelência apresentada por hospedeiros menos susceptíveis aos carrapatos depende da percepção pelos carrapatos de misturas específicas de voláteis liberados por estes hospedeiros.(AU)
Asunto(s)
Animales , Perros , Rhipicephalus sanguineus/parasitología , Benzaldehídos/farmacología , Metil n-Butil Cetona/farmacología , Preparaciones de Acción Retardada , Control de Ácaros y GarrapatasRESUMEN
Abstract Beagles are less susceptible to Rhipicephalus sanguineus sensu lato tick due to the production of the allomones benzaldehyde and 2-hexanone. Our previous published work showed that these compounds can reduce tick burden on susceptible dogs. Here we tested the hypothesis that an increase in repellent dose and release rate could increase repellent efficacy and persistence. Slow-release formulations of these compounds, with higher doses and release rates, were tested on artificially-infested dogs. Ten dogs were randomly assigned to two groups with five dogs each. The treated group received collars with slow-release formulations of the compounds attached, while the control group received collars with clean formulations attached. Five environmental infestations were performed, with the number of ticks (at all stages) on the dogs being counted once a day for 40 days. No significant increase in repellent efficacy was observed with the higher doses and release rates, whereas a greater persistence in repellent activity was observed. Treatment with the formulations resulted in a two-to-three-fold reduction in the number of immature stage ticks for up to three weeks. However, the number of adults was similar in both groups. Loss of repellent activity after the third week of testing coincided with a marked change in the relative release rates for the two compounds. It is hypothesized that relative amounts, rather than absolute amounts, of repellent release from slow-release formulations are important for repellent activity. We also hypothesize that the avoidance of less-preferred hosts by ticks relies on olfactory-mediated perception of specific blends of volatile cues from less preferred hosts.
Resumo Beagles são menos suscetíveis ao carrapato Rhipicephalus sanguineus sensu lato devido à produção de benzaldeído e 2-hexanona. Nosso trabalho anterior já publicado mostrou que esses compostos podem reduzir a carga de carrapatos em cães suscetíveis. Aqui testamos a hipótese de que um aumento na dose destes repelentes e na taxa de liberação poderia aumentar a eficácia e a persistência do efeito repelente. As formulações de liberação lenta destes compostos, com doses e taxas de liberação mais elevadas foram testadas em cães infestados artificialmente. Dez cães foram distribuídos aleatoriamente em dois grupos com cinco cães cada. O grupo tratado recebeu colares contendo formulações de liberação lenta dos compostos, enquanto o grupo controle recebeu colares com formulações limpas. Cinco infestações ambientais foram realizadas, com o número de carrapatos (em todas as fases) nos cães sendo contados, uma vez ao dia, por 40 dias. Não se observou aumento significativo na eficácia do repelente com doses e taxas de liberação mais elevadas e, enquanto observou-se maior persistência na atividade repelente. O tratamento com as formulações resultou em uma redução de duas a três vezes no número de carrapatos dos estágios imaturos, por até três semanas. No entanto, o número de adultos foi semelhante em ambos os grupos. A perda de atividade repelente após a terceira semana de teste coincidiu com uma mudança nas taxas de liberação relativa para os dois compostos. A hipótese é que as quantidades relativas, ao invés das quantidades absolutas de liberação lenta, são importantes para a atividade repelente. Então, a hipótese é de que a repelência apresentada por hospedeiros menos susceptíveis aos carrapatos depende da percepção pelos carrapatos de misturas específicas de voláteis liberados por estes hospedeiros.
Asunto(s)
Animales , Masculino , Femenino , Perros , Infestaciones por Garrapatas/veterinaria , Benzaldehídos/administración & dosificación , Rhipicephalus sanguineus/efectos de los fármacos , Enfermedades de los Perros/prevención & control , Repelentes de Insectos/administración & dosificación , Metil n-Butil Cetona/administración & dosificación , Infestaciones por Garrapatas/prevención & control , Factores de Tiempo , Estudios de Casos y Controles , Resultado del TratamientoRESUMEN
Beagles are less susceptible to Rhipicephalus sanguineus sensu lato tick due to the production of the allomones benzaldehyde and 2-hexanone. Our previous published work showed that these compounds can reduce tick burden on susceptible dogs. Here we tested the hypothesis that an increase in repellent dose and release rate could increase repellent efficacy and persistence. Slow-release formulations of these compounds, with higher doses and release rates, were tested on artificially-infested dogs. Ten dogs were randomly assigned to two groups with five dogs each. The treated group received collars with slow-release formulations of the compounds attached, while the control group received collars with clean formulations attached. Five environmental infestations were performed, with the number of ticks (at all stages) on the dogs being counted once a day for 40 days. No significant increase in repellent efficacy was observed with the higher doses and release rates, whereas a greater persistence in repellent activity was observed. Treatment with the formulations resulted in a two-to-three-fold reduction in the number of immature stage ticks for up to three weeks. However, the number of adults was similar in both groups. Loss of repellent activity after the third week of testing coincided with a marked change in the relative release rates for the two compounds. It is hypothesized that relative amounts, rather than absolute amounts, of repellent release from slow-release formulations are important for repellent activity. We also hypothesize that the avoidance of less-preferred hosts by ticks relies on olfactory-mediated perception of specific blends of volatile cues from less preferred hosts.
Asunto(s)
Benzaldehídos/administración & dosificación , Enfermedades de los Perros/prevención & control , Repelentes de Insectos/administración & dosificación , Metil n-Butil Cetona/administración & dosificación , Rhipicephalus sanguineus/efectos de los fármacos , Infestaciones por Garrapatas/veterinaria , Animales , Estudios de Casos y Controles , Perros , Femenino , Masculino , Infestaciones por Garrapatas/prevención & control , Factores de Tiempo , Resultado del TratamientoRESUMEN
Trypanosoma cruzi, the aetiological agent of Chagas disease possess extensive genetic diversity. This has led to the development of a plethora of molecular typing methods for the identification of both the known major genetic lineages and for more fine scale characterization of different multilocus genotypes within these major lineages. Whole genome sequencing applied to large sample sizes is not currently viable and multilocus enzyme electrophoresis, the previous gold standard for T. cruzi typing, is laborious and time consuming. In the present work, we present an optimized Multilocus Sequence Typing (MLST) scheme, based on the combined analysis of two recently proposed MLST approaches. Here, thirteen concatenated gene fragments were applied to a panel of T. cruzi reference strains encompassing all known genetic lineages. Concatenation of 13 fragments allowed assignment of all strains to the predicted Discrete Typing Units (DTUs), or near-clades, with the exception of one strain that was an outlier for TcV, due to apparent loss of heterozygosity in one fragment. Monophyly for all DTUs, along with robust bootstrap support, was restored when this fragment was subsequently excluded from the analysis. All possible combinations of loci were assessed against predefined criteria with the objective of selecting the most appropriate combination of between two and twelve fragments, for an optimized MLST scheme. The optimum combination consisted of 7 loci and discriminated between all reference strains in the panel, with the majority supported by robust bootstrap values. Additionally, a reduced panel of just 4 gene fragments displayed high bootstrap values for DTU assignment and discriminated 21 out of 25 genotypes. We propose that the seven-fragment MLST scheme could be used as a gold standard for T. cruzi typing, against which other typing approaches, particularly single locus approaches or systematic PCR assays based on amplicon size, could be compared.
Asunto(s)
Tipificación de Secuencias Multilocus/métodos , Parasitología/métodos , Trypanosoma cruzi/genética , GenotipoRESUMEN
La diabetes mellitus tipo 2 (DM2) es una enfermedad crónica no transmisible que representa una importante causa de morbimortalidad a nivel mundial. Para su control, se han desarrollado modelos de atención a las enfermedades crónicas; en el Perú, el Seguro Integral deSalud (SIS), apoyado por el Presupuesto por Resultados (PpR), y las normativas para el tratamiento de la DM2, proponen un tratamiento integral al paciente, en el marco del Modelo de Atención Integral de Salud del 2011. Esta investigación tuvo como objetivo caracterizar la atención ofrecida a los pacientes con DM2 a través del Seguro Integral de Salud en la red de servicios de la Región Callao del Ministerio de Salud, desde el punto de vista de los coordinadoresde la atención a la diabetes de los establecimientos de salud (puestos y centros de salud yhospitales) y de los niveles centrales de coordinación (microrredes, redes y dirección regional desalud). Para ello, se realizaron cuestionarios semiestructurados, que abordaron 5 dimensiones: Caracterización del establecimiento / nivel de coordinación, caracterización del coordinador, del proceso de atención a los pacientes con DM2, de los mecanismos de coordinación e identificaciónde las limitaciones para el desarrollo de las actividades de atención a la DM2. La población deestudio fue de 68 coordinaciones de salud. (...)La multiplicidad de funciones fue la dificultad reportada con mayor frecuencia por los coordinadores como limitante para el desarrollo de sus de coordinación, así como el subregistro de la información, el monitoreo insuficiente de las metaspor parte de los gestores, la ausencia de incentivos para el equipo de atención a la DM2 y elnúmero limitado de profesionales de la salud. Los coordinadores de hospitales señalaron ademásla inadecuación del plan de salud para la región, el uso del presupuesto programado en actividadesdistintas a la atención a la diabetes, la falta de coordinación con la oficina de planeamiento y la disponibilidad irregular de medicamentos. Este estudio evidenció deficiencias en la organización de los cuidados al paciente con DM2 del Seguro Integral de Salud, con uso muy limitado de la clasificación de riesgo, insuficiente número de profesionales, frecuente rotación y multiplicidadde funciones de los coordinadores, e insuficiente capacitación de los equipos de atención. Conello, podemos decir que en la Región Callao no existen redes integradas de atención de salud deacuerdo a las recomendaciones actuales del Modelo de Cuidados Crónicos, de la Organización Panamericana de la Salud y del Modelo de Atención Integral de Salud del Perú.
Type 2 diabetes mellitus (T2DM) is a non-communicable chronic disease considered amajor cause of morbidity and mortality worldwide. In order to control of this disease,there are care models for chronic diseases; in Peru, the Comprehensive Health Insurance(Seguro Integral de Salud-SIS), supported by the Performance-based Budgeting(Presupuesto por Resultados-PpR), and national regulations for the treatment of T2DM,propose a comprehensive patient management, under the Comprehensive Health CareModel (Modelo de Atención Integral de Salud, 2011). This research was aimed tocharacterize the care provided to patients with T2DM through the SIS, from the point ofview of the coordinators of care for diabetes health facilities (health posts and centers andhospitals) and central coordination levels (micro-networks, networks and Regional HealthSecretary) of Health Services System of Region Callao, of Peruvian Ministry of Health.Semi-structured questionnaires that addressed five main dimensions: Characterization ofthe establishment/coordination level, characterization of coordinators, characterization ofcare services provides to patients with T2DM and characterization of the mechanisms ofcoordination and identification of limitations for development of activities as perceivedby the coordinators, were performed. The population of the study was 68 coordinators. (...) Themultiplicity of functions was the most frequently reported difficulty related todevelopment of activities of coordinators; underreporting of information, inadequatemonitoring of targets by managers, lack of incentives for the care team for T2DM, andthe limited number of health professionals were other limitations. Hospitals coordinatorsalso noted the inadequacy of the health plan for the region, the use of the budget for otherthan scheduled diabetes care activities, and lack of coordination with the Planning Officeand irregular availability of drugs. This study showed deficiencies in the organization ofcare for patients with T2DM, with a very limited use of risk classification, insufficientnumber of health professionals, high turnover and multiple functions of coordinators, andinsufficient training of healthcare teams. Finally, we can say that in the Callao Region,there are not integrated health care networks according to the current recommendationsof the Chronic Care Model, the Pan American Health Organization and PeruvianComprehensive Health Care Model.
Asunto(s)
Humanos , Prestación Integrada de Atención de Salud , Enfermedad Crónica/terapia , Atención a la Salud , Perú , Medición de RiesgoRESUMEN
AIM: The aim of this study was to compare the soft tissue integration of submerged and non-submerged implants by means of periodontal parameter assessments and analysis. MATERIAL AND METHODS: Thirty-one patients, who received 42 non-submerged implants (ITI) and 48 submerged implants (3i), participated in the study. There was no significant difference (P>0.05) between both groups considering gender; educational level; handedness; toothbrushing frequency; the number of auxiliary devices used; and smoking habits. The parameters assessed were gingival index (GI), plaque index (PII), retention index (RI), pocket probing depth (PPD) and keratinized mucosa index. RESULTS: At evaluation, 66.67% of all sites showed a GI of 0; 72.22% a PI of 0, and 93.33% the absence of calculus. The average PPD was 2.56 mm in the non-submerged and 2.70 mm in the submerged group. With regard to the width of keratinized mucosa, 100% of the ITI implants showed a band of keratinized gingiva around the implant, whereas 14.58% in the 3i group showed a complete absence of keratinized mucosa. The intra-examiner reproducibility was 90.96% for all parameters and the Kendall tau-b analysis showed a powerless correlation between the chosen parameters for both studied groups. CONCLUSIONS: The study material showed no major differences between submerged and non-submerged dental implants regarding GI, PII, RI and PPD, except the width of keratinized mucosa. Regarding the presence of keratinized mucosa, there is a need for further longitudinal studies to elucidate a possible benefit of one implant system over the other.