RESUMEN

We present a case of Sneddon's syndrome with high titers of antiphospholipid antibodies (APLA), in which the leading symptom was an incapacitating memory defect. MRI revealed vasculitic lesions of the central nervous system (CNS). Therefore immunosuppressive therapy was started with steroids and cyclophosphamide pulses. The transient beneficial effects of such a therapy will be discussed.

Asunto(s)

Anticuerpos Antifosfolípidos/análisis , Enfermedades Cutáneas Vasculares/inmunología , Adulto , Trastornos Cerebrovasculares/diagnóstico , Trastornos Cerebrovasculares/etiología , Ciclofosfamida/uso terapéutico , Femenino , Humanos , Imagen por Resonancia Magnética , Trastornos de la Memoria/etiología , Enfermedades Cutáneas Vasculares/complicaciones , Enfermedades Cutáneas Vasculares/psicología , Síndrome