RESUMEN
No disponible
Asunto(s)
Humanos , Masculino , Preescolar , Pneumocystis carinii/virología , Insuficiencia Respiratoria/terapia , Infecciones por Coronavirus/diagnóstico por imagen , Infecciones por Coronavirus/tratamiento farmacológico , Betacoronavirus/efectos de los fármacos , Neumonía Viral/diagnóstico por imagen , Neumonía Viral/tratamiento farmacológico , Leucemia Bifenotípica Aguda/tratamiento farmacológico , Pancitopenia/complicaciones , Anfotericina B/administración & dosificación , Radiografía Torácica , Reacción en Cadena de la Polimerasa , Azitromicina/administración & dosificación , Hidroxicloroquina/administración & dosificación , Lopinavir/administración & dosificación , Insuficiencia Respiratoria/diagnóstico por imagen , Terapia por Inhalación de OxígenoAsunto(s)
COVID-19/diagnóstico , Pneumocystis carinii/aislamiento & purificación , Neumonía por Pneumocystis/diagnóstico , SARS-CoV-2 , Preescolar , Diagnóstico Diferencial , Progresión de la Enfermedad , Humanos , Masculino , Leucemia-Linfoma Linfoblástico de Células Precursoras/tratamiento farmacológicoRESUMEN
No disponible
Asunto(s)
Humanos , Infecciones por Coronavirus/tratamiento farmacológico , Coronavirus Relacionado al Síndrome Respiratorio Agudo Severo/patogenicidad , Lopinavir/farmacocinética , Ritonavir/farmacocinética , Síndrome Torácico Agudo/tratamiento farmacológico , Darunavir/farmacocinética , Cobicistat/farmacocinética , Toma de Decisiones , Formulación de Políticas , Pandemias/prevención & controlRESUMEN
The objective of this study was to assess the effectiveness of a catheter-related bloodstream infection (CR BSI) reduction programme and healthcare workers' compliance with recommendations. A 3-year surveillance programme of CR BSIs in all hospital settings was implemented. As part of the programme, there was a direct observation of insertion and maintenance of central venous catheters (CVCs) to determine performance. A total of 38 education courses were held over the study period and feedback reports with the results of surveillance and recommendations were delivered to healthcare workers every 6 months. A total of 6722 short-term CVCs were inserted in 4982 patients for 58 763 catheter-days. Improvements of compliance with hand hygiene was verified at the insertion (87·1-100%, P < 0·001) and maintenance (51·1-72·1%, P = 0·029) of CVCs; and the use of chlorhexidine for skin disinfection was implemented at insertion (35·7-65·4%, P < 0·001) and maintenance (33·3-45·9%, P < 0·197) of CVCs. There were 266 CR BSI incidents recorded with an annual incidence density of 5·75/1000 catheter-days in the first year, 4·38 in the second year [rate ratio (RR) 0·76, 95% confidence interval (CI) 0·57-1·01] and 3·46 in the third year (RR 0·60, 95% CI 0·44-0·81). The education programme clearly improved compliance with recommendations for CVC handling, and was effective in reducing the burden of CR BSIs.
Asunto(s)
Infecciones Relacionadas con Catéteres/epidemiología , Infecciones Relacionadas con Catéteres/prevención & control , Investigación sobre Servicios de Salud , Control de Infecciones/métodos , Sepsis/epidemiología , Sepsis/prevención & control , Adulto , Anciano , Actitud del Personal de Salud , Cateterismo/efectos adversos , Catéteres Venosos Centrales/efectos adversos , Desinfección/métodos , Desinfección/estadística & datos numéricos , Educación Médica , Femenino , Adhesión a Directriz , Humanos , Incidencia , Masculino , Persona de Mediana Edad , Centros de Atención TerciariaRESUMEN
The aggressive clinical course of pneumococcal endocarditis. A retrospective study was conducted between 2000 and 2005 in five patients with pneumococcal endocarditis were diagnosed at our center. Three female and 2 males, 13 to 76 year-old, were attended. Most of them had left valve endocarditis and were suffering from predisposing conditions. All of them developed distant complications as embolism or septic metastases. Two patients were successfully operated. Surgery was considered in another one but it was discarded due to her poor general condition. This was the only death in the series.
Asunto(s)
Endocarditis Bacteriana , Infecciones Neumocócicas , Adolescente , Adulto , Anciano , Endocarditis Bacteriana/complicaciones , Endocarditis Bacteriana/diagnóstico , Endocarditis Bacteriana/cirugía , Resultado Fatal , Femenino , Humanos , Masculino , Persona de Mediana Edad , Infecciones Neumocócicas/complicaciones , Infecciones Neumocócicas/diagnóstico , Infecciones Neumocócicas/cirugía , Estudios RetrospectivosRESUMEN
Realizamos un estudio retrospectivo de cinco casos diagnosticados de endocarditis neumocócica en nuestro hospital entre 2000 y 2005. Se trata de tres mujeres y dos varones con edades entre 13 y 76 años. La mayoría tuvieron afectadas las válvulas izquierdas y presentaron enfermedades predisponentes. Todos los pacientes presentaron enfermedad neumocócica a distancia en forma de embolismo o metástasis séptica. En dos pacientes se llevó a cabo cirugía cardíaca con éxito y en otro se desestimó por la mala situación clínica, siendo el único caso que falleció (AU)
A retrospective study was conducted between 2000 and 2005 in five patients with pneumococcal endocarditis were diagnosed at our center. Three female and 2 males, 13 to 76 year-old, were attended. Most of them had left valve endocarditis and were suffering from predisposing conditions. All of them developed distant complications as embolism or septic metastases. Two patients were successfully operated. Surgery was considered in another one but it was discarded due to her poor general condition. This was the only death in the series (AU)