RESUMEN
Elevated activities of serum aminotransferases are a common sign of liver disease and are observed more frequently among diabetics than in the general population. Whether this association is due to confounding factors is unknown. The authors investigated whether diabetes was significantly associated with elevated serum activity of alanine aminotransferase (ALT) after adjustment for factors common to both diabetes and raised ALT. Data from 2,999 men and women aged 20-74 years representative of the Mexican American population of the southwestern United States were obtained from the Hispanic Health and Nutrition Examination Survey (1982-1984). Approximately 6% of men and 2% of women had elevated serum ALT activity (>43 IU/liter). The odds ratio for diabetes as a predictor of elevated ALT was 4.1 (95% confidence interval 2.3-7.6) adjusted for age and sex, which decreased to 3.0 (95% confidence interval 0.92-9.74) after adjustment for age, sex, body mass index, alcohol consumption, and other factors. In addition to diabetes, body mass index was also significantly (p < 0.05) associated with elevated ALT activity. Heavier alcohol consumption and male sex increased the likelihood of elevated ALT, whereas coffee consumption reduced it. Diabetes and liver injury appear to be associated, even with control for factors in common.
Asunto(s)
Alanina Transaminasa/sangre , Diabetes Mellitus/enzimología , Americanos Mexicanos , Adulto , Distribución por Edad , Anciano , Consumo de Bebidas Alcohólicas/sangre , Consumo de Bebidas Alcohólicas/etnología , Intervalos de Confianza , Factores de Confusión Epidemiológicos , Diabetes Mellitus/etnología , Femenino , Humanos , Hepatopatías/enzimología , Hepatopatías/etnología , Masculino , Americanos Mexicanos/estadística & datos numéricos , Persona de Mediana Edad , Análisis Multivariante , Oportunidad Relativa , Distribución por Sexo , Sudoeste de Estados Unidos/epidemiologíaRESUMEN
Canda's response to the AIDS epidemic is orchestrated at the Federal Government level by the Federal Center for AIDS (FCA), created in 1987. The Center is made up of six bureaus. The Bureau of Program Analysis and Resoures is the focal point for policy and program development. The Bureau of Prevention and Services program focuses on education and awareness strategies, liaison with health care workers and community groups, and the psychosocial aspects of the epidemic. The Bureau of Epidemiology and Surveillance monitors trends and assesses the extent of the disease. The Bureau of Laboratories and Research, with its divisions of retrovirology and immunology, provides reference services for laboratories engaged in HIV screening and diagnosis, an collaborates with national and international researchers. The Bureau of External Cooperation promotes international collaboration in all áreas Bureau of Clinical Studies promotes studies and drugs and vaccines. Important roles in the fight against AIDS are also played by the National Health Research and Development Program, privincial and territorial governments, and community-based support groups. Canada is an active participant in international efforts to combat AIDS through WHO, PAHO, and other agencies
Asunto(s)
Síndrome de Inmunodeficiencia Adquirida , Programas Nacionales de Salud/organización & administración , CanadáRESUMEN
Canda's response to the AIDS epidemic is orchestrated at the Federal Government level by the Federal Center for AIDS (FCA), created in 1987. The Center is made up of six bureaus. The Bureau of Program Analysis and Resoures is the focal point for policy and program development. The Bureau of Prevention and Services program focuses on education and awareness strategies, liaison with health care workers and community groups, and the psychosocial aspects of the epidemic. The Bureau of Epidemiology and Surveillance monitors trends and assesses the extent of the disease. The Bureau of Laboratories and Research, with its divisions of retrovirology and immunology, provides reference services for laboratories engaged in HIV screening and diagnosis, an collaborates with national and international researchers. The Bureau of External Cooperation promotes international collaboration in all areas Bureau of Clinical Studies promotes studies and drugs and vaccines. Important roles in the fight against AIDS are also played by the National Health Research and Development Program, privincial and territorial governments, and community-based support groups. Canada is an active participant in international efforts to combat AIDS through WHO, PAHO, and other agencies