RESUMEN
Experiments on 30 rabbits, as well as clinical studies on 180 patients with cerebral circulation disorders were carried out. It was found that in patients with hypertensive disease complication, thyroid hyperactivity was observed only in the age group of 35 to 45 years. It was also found that in the patients with hypertensive disease and the complications of the latter, repeated stresses intensified the neurosecretory functions of the hypophysis and the hypothalamus: this, in its turn, influenced the hormone-synthetizing function of the thyroid. The chronic hyperthyroid syndrome present in those patients led to an increased oxygen consumption by tissues, slowed down the electron transport along the respiratory chain, increased the content of iodine and protein, and intensified the effects of pressor agents, i. e. aggravated the symptoms of the hypertensive disease. All those factors play a definite role in the mechanism of the development of the cerebral circulation disorders in hypertensive patients.
Asunto(s)
Trastornos Cerebrovasculares/fisiopatología , Glándula Tiroides/fisiopatología , Adulto , Animales , Hemorragia Cerebral/fisiopatología , Trastornos Cerebrovasculares/etiología , Humanos , Hipertensión/fisiopatología , Hipertensión Renal/complicaciones , Hipertiroidismo/complicaciones , Hipertiroidismo/fisiopatología , Arteriosclerosis Intracraneal/fisiopatología , Ataque Isquémico Transitorio/fisiopatología , Masculino , Persona de Mediana Edad , ConejosRESUMEN
The authors studied clinical forms of hypothalamic disturbances in 180 patients with disorders of cerebral circulation. The following syndromes of hypothalamic disorders were distinguished: gastro-intestinal, cardio-vascular, endocrinometabolical, vegetative-endocrinological. In 18 deceased the neurosecretion of the hypophysis and hypothalamus was studied. It was possible to establish the form of neurosecretion movement and its existence or absence in the hypothalamus. In patients who died following an acute disorders of cerebral circulation, both factors in the opinion of the authors, play a certain role in the pathogenesis of a cerebral stroke.