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Eur J Clin Invest ; 31(3): 201-7, 2001 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-11264646

RESUMEN

Moderate intensity exercise reduces postprandial triacylglycerol (TG) concentrations. We tested whether this reflects increased TG clearance. Eight normotriglyceridaemic men, aged 48.3 +/- 7.3 years (mean +/- SD), performed two oral fat tolerance tests (blood samples taken in the fasted state and for six hours after a high-fat meal containing 1.00 g fat, 0.97 g carbohydrate, 58 kJ energy kg-1 fat-free body mass) and two intravenous fat tolerance tests (blood samples in the fasted state and after a bolus injection of Intralipid, 0.1 g fat kg-1 body mass). The afternoon before one oral and one intravenous test, subjects walked briskly for 90 min; no exercise was performed before the control tests. Prior exercise reduced fasting TG concentration similarly in the oral (16 +/- 7 %) (mean +/- SEM) and intravenous (18 +/- 7 %) tests, and reduced postprandial TG concentrations in the oral test by 18 +/- 6 % (all P < 0.05). However, prior exercise did not increase Intralipid clearance (disappearance curve slopes: control, 4.69 +/- 0.49 % min-1; exercise, 4.85 +/- 0.40 % min-1). These data suggest that mechanisms other than increased TG clearance mediate the lower postprandial TG concentrations seen after moderate exercise.


Asunto(s)
Ejercicio Físico/fisiología , Lipoproteínas/sangre , Periodo Posprandial/fisiología , Triglicéridos/sangre , Administración Oral , Grasas de la Dieta/administración & dosificación , Prueba de Esfuerzo , Ayuno , Emulsiones Grasas Intravenosas/administración & dosificación , Ácidos Grasos no Esterificados/sangre , Humanos , Inyecciones Intravenosas , Lípidos/sangre , Masculino , Persona de Mediana Edad , Triglicéridos/farmacocinética , Caminata/fisiología
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