RESUMEN

The structures of seldomycin factors 1 and 2 have been determined by consideration of chemical degradation and spectral properties. Factor 1, also known as XK-88-1, is shown to be 6-O-(2-amino-2-deoxy-alpha-D-xylopyranosyl) paromamine (1) and factor 2, also known as XK-88-2, is shown to be 4'-deoxy-neamine (2). Mass spectral evidence has been obtained that suggests the most probable structure for seldomycin factor 3, also known as XK-88-3, is 6'-amino-6'-deoxyseldomycin factor 1 (12).

Asunto(s)

Antibacterianos , Amino Azúcares/aislamiento & purificación , Aminoglicósidos , Fenómenos Químicos , Química , Hidrólisis , Espectrometría de Masas , Métodos , Conformación Molecular , Oxidación-Reducción

Asunto(s)

Antibacterianos , Aminoglicósidos , Fenómenos Químicos , Química , Espectroscopía de Resonancia Magnética , Espectrometría de Masas , Métodos , Conformación Molecular