RESUMEN
We evaluated health risks associated with perfluorinated and polyfluorinated alkyl substances (PFASs) found in drinking water applying human risk assessment (HRA) methodology. Using data on worldwide occurrence of PFASs in drinking water and recent guidelines for PFASs in drinking water, we applied four scenarios based on different toxicological threshold values to calculate age-dependent risk quotients (RQ) for different PFASs. The mean concentrations of the most frequently detected compounds (PFOS and PFOA) were highest in North America (99.2 and 30.7 ng L-1, respectively), and lowest in Asia (PFOS: 3.0 ng L-1) and Europe (PFOA: 4.87 ng L-1). Using HRA methodology and maximum reported concentrations, only PFOS and PFOA, examined individually, showed any threat to human health. Specifically, calculations with the average and maximum concentrations of PFOS showed RQ values higher than 0.2 or 1, respectively, for some age groups under specific scenarios. Similarly, using maximum PFOA concentrations, a RQ equal to 0.2 for infants up to 3 months was calculated under scenario 4. Regional differences on RQ values were observed when PFOS concentrations from Europe, North America and Asia were used. Estimation of the human health risk due to mixtures of PFASs using average concentrations showed that the RQmix was higher than 0.2 for infants up to 3 months (scenario 3) and infants and children up to 6 years old (scenario 4). More importantly, evaluation of the guideline values set by the EU and the Health Advisory Levels issued by the USEPA resulted (under some scenarios) in RQ values higher than 0.2 for PFOS and PFOA for specific age groups, indicating that further discussion is needed for the monitoring and prioritization of these compounds.
Asunto(s)
Agua Potable , Ácidos Alcanesulfónicos , Asia , Caprilatos , Niño , Preescolar , Europa (Continente) , Fluorocarburos , Humanos , Lactante , América del Norte , Medición de Riesgo , Contaminantes Químicos del AguaRESUMEN
The Mediterranean basin is a region of particular interest for studying atmospheric aerosols due to the large variety of air masses it receives, and its sensitivity to climate change. In this study we use the newest collection (C006) of aerosol optical depth from MODIS-Aqua, from which we also derived the fine-mode fraction and Ångström exponent over the last 12years (i.e., from 2002 to 2014), providing the longest analyzed dataset for this region. The long-term regional optical depth average is 0.20±0.05, with the indicated uncertainty reflecting the inter-annual variability. Overall, the aerosol optical depth exhibits a south-to-north decreasing gradient and an average decreasing trend of 0.0030 per year (19% total decrease over the study period). The correlation between the reported AOD observations with measurements from the ground AERONET stations is high (R=0.76-0.80 depending on the wavelength), with the MODIS-Aqua data being slightly overestimated. Both fine-fraction and Ångström exponent data highlight the dominance of anthropogenic aerosols over the northern, and of desert aerosols over the southern part of the region. Clear intrusions of desert dust over the Eastern Mediterranean are observed principally in spring, and in some cases in winter. Dust intrusions dominate the Western Mediterranean in the summer (and sometimes in autumn), whereas anthropogenic aerosols dominate the sub-region of the Black Sea in all seasons but especially during summer. Fine-mode optical depth is found to decrease over almost all areas of the study region during the 12-year period, marking the decreasing contribution of anthropogenic particulate matter emissions over the study area. Coarse-mode aerosol load also exhibits an overall decreasing trend. However, its decrease is smaller than that of fine aerosols and not as uniformly distributed, underlining that the overall decrease in the region arises mainly from reduced anthropogenic emissions.