RESUMEN
A double-blind comparison of Hexabrix and Renografin-76 for intravenous digital subtraction angiography (IV-DSA) revealed a slightly greater percentage of patients with good or satisfactory examinations who received Hexabrix. There were fewer perturbations of the ECG, less alteration in the diastolic blood pressure, and no serious adverse reactions noted in the Hexabrix group. However, the differences between the groups were not statistically significant. When used for IV-DSA, the lower osmolality associated with Hexabrix offers the theoretic advantages of (1) reduced osmotic load and (2) diminished alteration in central blood volume.
Asunto(s)
Angiografía/métodos , Medios de Contraste , Diatrizoato de Meglumina , Diatrizoato/análogos & derivados , Yodobenzoatos , Ácidos Triyodobenzoicos , Adulto , Anciano , Conversión Analogo-Digital , Ensayos Clínicos como Asunto , Método Doble Ciego , Combinación de Medicamentos , Electrocardiografía , Femenino , Corazón/efectos de los fármacos , Humanos , Ácido Yoxáglico , Masculino , Persona de Mediana Edad , Técnica de SustracciónRESUMEN
A double-blind parallel comparison of iopamidol and metrizamide for myelography was performed in 36 patients. Sixteen adverse reactions were noted in 10 patients who received metrizamide. Six adverse reactions were reported in five patients who received iopamidol. There was no appreciable difference in the radiographic opacification.
Asunto(s)
Medios de Contraste , Ácido Yotalámico/análogos & derivados , Metrizamida , Mielografía/métodos , Medios de Contraste/efectos adversos , Método Doble Ciego , Femenino , Humanos , Yopamidol , Ácido Yotalámico/efectos adversos , Masculino , Metrizamida/efectos adversosRESUMEN
The lumbosacral nerve roots and their relation to the lateral recess in the lumbar region were studied by computed tomography both in anatomic specimens from six cadavers and in vivo in 100 patients with or without disk herniation. The anatomic and tomodensitometric correlations are discussed. The normal morphology and contents of the lumbar spinal canal can be used as a guide to radiologic diagnostic exploration, which in turn can indicate the etiology and extent of lumbar sciatica and the course of treatment.
Asunto(s)
Desplazamiento del Disco Intervertebral/diagnóstico por imagen , Vértebras Lumbares/diagnóstico por imagen , Raíces Nerviosas Espinales/diagnóstico por imagen , Tomografía Computarizada por Rayos X/métodos , Diagnóstico Diferencial , HumanosRESUMEN
To analyse the anatomo-radiological correlation of the spine and spinal cord, 22 formalized, frozen anatomical specimens corresponding to different regions of the spinal column (8 cervical, 5 dorsal, and 9 lumbar) were studied by CT scans on axial, sagittal and coronal planes and by contact radiography after they were cut into anatomical slices in order to clarify the normal CT anatomy of the spinal column. The results obtained from CT patient scans, performed exclusively on the axial plane, were compared with those obtained from the anatomical specimens (both CT and contrast radiography). High resolution CT programs were used, enabling us to obtain better individualization of the normal structures contained in the spinal column. Direct sagittal and coronal sections were performed on the specimens in order to get further anatomo-radiological information. Enhanced CT studies of the specimens were also available because of the air already present in the subarachnoid spaces. Excellent visualization was obtained of bone structures, soft tissue and the spinal cord. High CT resolution of the spine appears to be an excellent neuroradiological procedure to study the spine and spinal cord. A metrizamide CT scan is, however, necessary when a normal unenhanced CT scan is insufficient for diagnosis and when the spinal cord is not clearly visible, as often happens at the cervical level. Clinical findings are certainly very useful to ascertain the exact CT level and to limit the radiation exposure.